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zondag 4 november 2018

The Lancet: [Comment] Incarceration, drug use, and infectious diseases: a syndemic still not addressed

[Comment] Incarceration, drug use, and infectious diseases: a syndemic still not addressed
Substantial progress has been made in reducing HIV and, to a lesser extent, hepatitis C virus (HCV) incidence among people who inject drugs (PWID) globally.1 However, specific populations of PWID, particularly those who are incarcerated, are often overlooked or left out of interventions designed to reduce HIV and HCV transmission. In particular, we know that the period immediately following release from incarceration is a time of very high risk for HIV and HCV transmission as well as opioid-related overdose, largely owing to relapse to drug use post-release.
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[Newsdesk] Violence and community mistrust hamper Ebola response
Ongoing conflict and chronic community mistrust are impeding control of the Ebola virus outbreak in DR Congo. Sophie Cousins reports.
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[Corrections] Corrections
Khalil IA, Troeger T, Blacker BF, et al. Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990–2016. Lancet Infect Dis 2018; 18: 1229–40—In this Article, the copyright line should have been "© 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license." This correction has been made to the online version as of Oct 30, 2018.
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[Articles] Assessment of blood enterovirus PCR testing in paediatric populations with fever without source, sepsis-like disease, or suspected meningitis: a prospective, multicentre, observational cohort study
Testing for enterovirus in blood by PCR should be an integral part of clinical practice guidelines for infants aged 2 years or younger. This testing could decrease the length of hospital stay and reduce exposure to antibiotics for low-risk patients admitted to the emergency department with febrile illness.
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[Comment] Blood PCR testing for enteroviruses in young children
Enteroviruses are common causes of febrile illness and CNS infection in young children.1 Rapid molecular detection of enteroviruses in cerebrospinal fluid (CSF) decreases exposure to unnecessary antimicrobials, length of stay, and health-care costs by identifying an alternative cause to bacterial or herpes simplex virus infection.2,3 Although CSF is commonly tested for enteroviruses in young children undergoing lumbar puncture, and enteroviruses can now be detected with a commercial multiplex syndromic PCR panel,4 blood is not routinely tested and is not included in many clinical management guidelines for febrile infants.
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