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Nature Reviews Urology - Table of Contents alert Volume 15 Issue 10

Nature Reviews Urology

TABLE OF CONTENTS

October 2018 Volume 15, Issue 10

Comment
Research Highlights
News & Views
Reviews
Perspectives

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Comment

Biomarker challenges for immune checkpoint inhibitors in urothelial carcinoma   
Tom Powles & Laura Morrison
pp585 - 587 | doi:10.1038/s41585-018-0056-3
Full Text | PDF
Collection: Nobel Prize in Physiology or Medicine 2018


Research Highlights

Unearthing roles for the gut microbiome
Annette Fenner
p589 | doi:10.1038/s41585-018-0068-z
PDF
Collection: Cancer at Nature Research



Visualizing hypoxia
Louise Stone
p590 | doi:10.1038/s41585-018-0061-6
PDF
Collection: Cancer at Nature Research



IL-6 mediates high-fat diet-induced tumour growth
Conor A. Bradley
pp590 - 591 | doi:10.1038/s41585-018-0063-4
PDF
Collection: Cancer at Nature Research



Efficacy of a PSMA-targeted nanoparticle
Conor A. Bradley
pp590 - 591 | doi:10.1038/s41585-018-0067-0
PDF
Collection: Cancer at Nature Research



BCG enriches Treg cells
Annette Fenner
p591 | doi:10.1038/s41585-018-0075-0
PDF
Collection: Cancer at Nature Research



News & Views

Pembrolizumab: patient selection or immune intensification?
Ravi A. Madan & James L. Gulley
pp593 - 594 | doi:10.1038/s41585-018-0076-z
PDF
Collection: Cancer at Nature Research



Genomic diversity in low-risk disease: present and future
Vidit Sharma & R. Jeffrey Karnes
pp594 - 596 | doi:10.1038/s41585-018-0073-2
PDF
Collection: Cancer at Nature Research



EMA and FDA prune the checkpoint inhibitor treatment landscape
Min Yuen Teo & Jonathan E. Rosenberg
pp596 - 597 | doi:10.1038/s41585-018-0074-1
PDF
Collection: Cancer at Nature Research



Reviews

Epigenetic modifiers: activities in renal cell carcinoma   
Aguirre A. de Cubas & W. Kimryn Rathmell
pp599 - 614 | doi:10.1038/s41585-018-0052-7
Renal cell carcinomas (RCCs) harbour mutations in genes encoding chromatin modifiers, which have integral roles in genome maintenance and epigenetic regulation. Here, the authors review the mutational landscape and roles of chromatin modifiers as co-drivers in RCC, highlighting therapeutic opportunities.
Full Text | PDF
Collection: Cancer at Nature Research


Mechanisms of BCG immunotherapy and its outlook for bladder cancer   
Caroline Pettenati & Molly A. Ingersoll
pp615 - 625 | doi:10.1038/s41585-018-0055-4
BCG immunotherapy is the gold-standard treatment for non-muscle-invasive bladder cancer at high risk of recurrence or progression, but many questions remain unanswered regarding its mechanism of action. The authors describe current knowledge of these mechanisms and discuss ways of augmenting BCG immunotherapy.
Full Text | PDF
Collection: Cancer at Nature Research


Perspectives

Landmarks in prostate cancer   
Niranjan J. Sathianathen, Badrinath R. Konety et al.
pp627 - 642 | doi:10.1038/s41585-018-0060-7
In this Timeline article, the authors discuss studies that have improved our understanding of prostate cancer and influenced management of this disease.
Full Text | PDF



The role of ketoconazole in current prostate cancer care   
Vaibhav Patel, Bobby Liaw & William Oh
pp643 - 651 | doi:10.1038/s41585-018-0077-y
Despite having efficacy without a survival benefit in castration-resistant prostate cancer, ketoconazole has considerable advantages such as low cost. Here, the authors discuss the clinical experience with ketoconazole, emphasizing treatment timing and sequencing, and highlight patient populations that might benefit.
Full Text | PDF



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