We bring you the latest news from the healthcare about the health care in the United Kingdom.

vrijdag 19 oktober 2018

Nature Reviews Neuroscience contents November 2018 Volume 19 Number 11

Nature Reviews Neuroscience


Advertisement
Focal Point on Kobe 

A seismic shift - How Kobe rebuilt itself after a devastating earthquake and turned into a biotechnology hub
TABLE OF CONTENTS

November 2018 Volume 19, Issue 11

Research Highlights
Reviews
Perspectives

Advertisement
 
Imagine what you can do with a 360° view of locomotion A key endpoint to evaluate efficacy of Parkinson's disease therapies is changes in movement and balance. Typically, these endpoints are measured using established methods like rotarod tests that detect overt changes. At Charles River, we have developed a quantitative fine motor kinematics method to measure small changes in locomotor activity in rodent models of Parkinson's disease to develop a movement "signature".
 
 



Advertisement
Astrocyte Development & Function Poster

This new poster was developed in collaboration with Benjamin Deneen, PhD., Debosmita Sardar, PhD., and Yi-Ting Cheng, MS. at the Baylor College of Medicine. Explore the most current findings on astrocytes' development, subtype diversity, CNS function and role in disease. 

Download poster
 
Advertisement
===================================
Register for the latest nature.com webcast

Role for NaV1.3 in the developing cerebral cortex - Wednesday, 31 October 2018 

Register for FREE today 

Sponsored by Advanced Cell Diagnostics
==================================
 

Research Highlights

Rewarding gut feeling
Sian Lewis
p639 | doi:10.1038/s41583-018-0075-3
Vagal afferents projecting from the gut to the brainstem and then relayed on to the midbrain carry reward signals that trigger dopamine release in the dorsal striatum.
PDF



In or out of synch
Natasha Bray
pp640 - 641 | doi:10.1038/s41583-018-0074-4
In a genetic mouse model related to schizophrenia, restoring the excitability of parvalbumin-expressing interneurons in hippocampal CA1 ameliorates network dysfunction and behavioural deficits.
PDF



It's about time
Katherine Whalley
pp640 - 641 | doi:10.1038/s41583-018-0066-4
Study shows that population activity in the rat lateral entorhinal cortex can encode the passage of time, which may contribute to temporal aspects of episodic memory.
PDF



Incidental associations
Sian Lewis
p641 | doi:10.1038/s41583-018-0069-1
Hippocampal cannabinoid 1 receptors are shown to be involved in the formation of incidental associations between pairs of low-salience sensory stimuli, which can then become indirectly associated with certain cues and thus influence behaviour.
PDF



A position on vision
Darran Yates
p642 | doi:10.1038/s41583-018-0076-2
PDF



Number crunching
Katherine Whalley
p642 | doi:10.1038/s41583-018-0073-5
Number neurons encoding symbolic and nonsymbolical representations of numerical value are identified in the human medial temporal lobe
PDF



Nature Reviews Neuroscience
EVENT
Neurodegenerative Diseases: Biology & Therapeutics
28.11.18
Cold Spring Harbor, USA
More science events from

Reviews

The neural mechanisms and circuitry of the pair bond   
Hasse Walum & Larry J. Young
pp643 - 654 | doi:10.1038/s41583-018-0072-6
Recent research advances have yielded fresh insights into the fundamental neural processes underlying pair bonding. In this Review, Walum and Young discuss how neural representations of a partner become inherently rewarding, providing intriguing insights into the neural origins of love.
Full Text | PDF



CNS infection and immune privilege   
John V. Forrester, Paul G. McMenamin & Samantha J. Dando
pp655 - 671 | doi:10.1038/s41583-018-0070-8
Traditionally, the CNS is described to have immune privilege, largely because of its immunological barriers. Here, Forrester, McMenamin and Dando describe how this immune privilege may sometimes not be beneficial, as it enables invading pathogens to exist as latent CNS infections.
Full Text | PDF



Imaging-based parcellations of the human brain   
Simon B. Eickhoff, B. T. Thomas Yeo & Sarah Genon
pp672 - 686 | doi:10.1038/s41583-018-0071-7
The brain can be parcellated into areas or networks with different structural or functional properties. Eickhoff, Yeo and Genon describe various imaging-based strategies to parcellate the human brain, including those based on local properties, such as cytoarchitecture, and global properties, such as connectivity.
Full Text | PDF



Imaging the evolution and pathophysiology of Alzheimer disease   
William Jagust
pp687 - 700 | doi:10.1038/s41583-018-0067-3
Various techniques can be used to image aspects of the pathophysiology of Alzheimer disease in humans, notably protein deposition and neurodegeneration. In this Review, William Jagust discusses how human neuroimaging studies have shaped our understanding of this disease.
Full Text | PDF



Advertisement
Do you have a career question? 

The Naturejobs podcast features one-on-one Q&As, panel discussions and other exclusive content to help scientists with their careers. Hosted on the Naturejobs blog, the podcast is also available on iTunes and Soundcloud.

Listen today >>
 

Perspectives

Maintenance, reserve and compensation: the cognitive neuroscience of healthy ageing   
Roberto Cabeza, Marilyn Albert, Sylvie Belleville, Fergus I. M. Craik, Audrey Duarte et al.
pp701 - 710 | doi:10.1038/s41583-018-0068-2
Age-related changes in cognitive ability are the focus of a growing field of research. Cabeza, Rajah and colleagues aim to promote clarity in the field by agreeing upon consensual definitions for three widely discussed concepts: maintenance, compensation and reserve.
Full Text | PDF



Advertisement
Alzheimer's Disease Therapeutics: Alternatives to Amyloid

December 11, 2018, NYC

Featuring Rudolph Tanzi, PhD, of Harvard Medical School, this symposium will highlight non-amyloid mechanisms driving Alzheimer's disease including mitochondrial factors, the vasculature, and autophagy, and discuss strategies to identify new therapeutic targets. Abstracts Nov 2.

Register
 
Advertisement
Nature Briefing is an essential round-up of science news, opinion and analysis, free in your inbox every weekday. With Nature Briefing, we'll keep you updated on the latest research, so you can focus on yours.

Click here to sign up.
 
nature events
Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here.
Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com
More Nature Events

This email has been sent to dezorgsector.uk@gmail.com.

If you no longer wish to receive the email alerts from Nature Reviews Neuroscience click here to unsubscribe .
If you wish to discontinue all email services from Nature Research please click here to unsubscribe .

For further technical assistance, please contact our registration department.

For print subscription enquiries, please contact our subscription department.

For other enquiries, please contact our customer feedback department.

Macmillan Publishers Limited is a company incorporated in England & Wales under company number 785998 & whose registered office is located at The Campus, 4 Crinan Street, London, N1 9XW. Nature Research | One New York Plaza, Suite 4500 | New York | NY 10004-1562 | USA

Nature is part of Springer Nature. © 2018 Springer Nature Limited. All rights reserved.

Springer Nature