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dinsdag 16 oktober 2018

Nature Reviews Cardiology - Table of Contents alert Volume 15 Issue 11

Nature Reviews Cardiology


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TABLE OF CONTENTS

November 2018 Volume 15, Issue 11

Obituary
Research Highlights
News & Views
Reviews

Obituary

Bongani Mawethu Mayosi   
Ntobeko A. B. Ntusi
p649 | doi:10.1038/s41569-018-0093-x
Full Text | PDF



Research Highlights

Aspirin for primary prevention of CVD: a matter of balance
Irene Fernández-Ruiz
p651 | doi:10.1038/s41569-018-0096-7
PDF
Series: Prevention of cardiovascular disease



Tafamidis: a new treatment for ATTR cardiomyopathy
Alexandra Le Bras
p652 | doi:10.1038/s41569-018-0089-6
PDF



Drug-coated balloons – another option for small-vessel disease
Irene Fernández-Ruiz
p652 | doi:10.1038/s41569-018-0088-7
PDF



No benefit of rivaroxaban in HF with sinus rhythm
Gregory B. Lim
p653 | doi:10.1038/s41569-018-0082-0
PDF



Rivaroxaban for prevention of VTE
Gregory B. Lim
p653 | doi:10.1038/s41569-018-0083-z
PDF



Early invasive assessment of NSTE-ACS
Gregory B. Lim
p653 | doi:10.1038/s41569-018-0084-y
PDF



Endocarditis: oral versus intravenous antibiotics
Alexandra Le Bras
p653 | doi:10.1038/s41569-018-0095-8
PDF



No benefit of n-3 fatty acid supplements in diabetes
Gregory B. Lim
p654 | doi:10.1038/s41569-018-0090-0
PDF



3D virtual heart to guide VT ablation
Alexandra Le Bras
p654 | doi:10.1038/s41569-018-0102-0
PDF



Cardiovascular safety of lorcaserin
Gregory B. Lim
p655 | doi:10.1038/s41569-018-0092-y
PDF



Ticagrelor not superior to DAPT after PCI
Alexandra Le Bras
p655 | doi:10.1038/s41569-018-0099-4
PDF



No benefit of MitraClip for secondary mitral regurgitation in heart failure
Irene Fernández-Ruiz
p655 | doi:10.1038/s41569-018-0081-1
PDF



Telemedicine for HF management
Irene Fernández-Ruiz
p656 | doi:10.1038/s41569-018-0094-9
PDF



Perivascular fat mapping predicts cardiac death
Alexandra Le Bras
p656 | doi:10.1038/s41569-018-0101-1
PDF



Assisted reproductive technologies increase risk of hypertension in offspring
Gregory B. Lim
p656 | doi:10.1038/s41569-018-0091-z
PDF



Nature Reviews Cardiology
EVENT
ICI2018 International Conference for Innovations in Cardiovascular Systems
02.12.18
Tel Aviv-Yako, Israel
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News & Views

Detection of atrial fibrillation using a smartwatch
Ki H. Chon & David D. McManus
pp657 - 658 | doi:10.1038/s41569-018-0057-1
PDF



Reviews

Cell therapy trials for heart regeneration – lessons learned and future directions   
Philippe Menasché
pp659 - 671 | doi:10.1038/s41569-018-0013-0
The conflicting results of cell therapy clinical trials for heart regeneration have led to some confusion over the efficacy of this approach. This Review summarizes the main outcomes of these studies and gives perspectives for future cell-based regenerative trials largely based on the primary therapeutic target: regeneration of lost myocardium by exogenous cells or promotion of intrinsic repair though paracrine signalling.
Full Text | PDF
Focus: Cardiac development and regeneration Stem cells from development to the clinic


The Hippo pathway in the heart: pivotal roles in development, disease, and regeneration   
Jun Wang, Shijie Liu, Todd Heallen & James F. Martin
pp672 - 684 | doi:10.1038/s41569-018-0063-3
This Review summarizes the current understanding on the roles of the Hippo–YAP pathway in cardiac development, growth, homeostasis, disease, and regeneration, with a particular focus on the roles of the Hippo–YAP pathway in endogenous cardiac muscle renewal, including the pivotal role of this pathway in regulating cardiomyocyte proliferation, differentiation, stress response, and mechanical signalling.
Full Text | PDF
Focus: Cardiac development and regeneration


Notch and interacting signalling pathways in cardiac development, disease, and regeneration   
Donal MacGrogan, Juliane Münch & José Luis de la Pompa
pp685 - 704 | doi:10.1038/s41569-018-0100-2
In this Review, de la Pompa and colleagues describe the role of the Notch pathway during the differentiation and patterning of cardiac tissues and in valve and ventricular chamber development, discussing the crosstalk with other signalling pathways, how defective Notch signalling is linked to congenital heart diseases, and the relevance of the Notch pathway in heart regeneration and repair.
Full Text | PDF
Focus: Cardiac development and regeneration


The deployment of cell lineages that form the mammalian heart   
Sigolène M. Meilhac & Margaret E. Buckingham
pp705 - 724 | doi:10.1038/s41569-018-0086-9
In this Review, Meilhac and Buckingham discuss the origin of cardiac cell populations, their lineage relationships and the genes that regulate their behaviour and differentiation. Characterizing the progenitor cells that form the heart and the gene regulatory networks controlling their deployment is of major importance for understanding the origin of congenital heart malformations and for developing cardiac regeneration therapies.
Full Text | PDF
Focus: Cardiac development and regeneration


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