We bring you the latest news from the healthcare about the health care in the United Kingdom.

maandag 3 september 2018

The Lancet: [Articles] Pharyngeal electrical stimulation for early decannulation in tracheotomised patients with neur...

[Articles] Pharyngeal electrical stimulation for early decannulation in tracheotomised patients with neurogenic dysphagia after stroke (PHAST-TRAC): a prospective, single-blinded, randomised trial
In patients with stroke and subsequent tracheotomy, PES increased the proportion of patients who were ready for decannulation in this study population, many of whom received PES within a month of their stroke. Future trials should confirm whether PES is beneficial in tracheotomised patients who receive stimulation similarly early after stroke and explore its effects in other cohorts.
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[Articles] Plasma and CSF biomarkers for the diagnosis of Alzheimer's disease in adults with Down syndrome: a cross-sectional study
Plasma NfL and CSF biomarkers have good diagnostic performance to detect Alzheimer's disease in adults with Down syndrome. Our findings support the utility of plasma NfL for the early detection of Alzheimer's disease in Down syndrome in clinical practice and clinical trials.
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[Comment] Diagnostic biomarkers of Alzheimer's disease in Down syndrome
About 6 million people worldwide have Down syndrome, and these individuals represent the largest population genetically predisposed to developing early-onset Alzheimer's disease.1 Although progress has been made in diagnosing Alzheimer's disease dementia in people with Down syndrome,2,3 making a definitive diagnosis remains a major challenge owing to substantial variability in baseline cognitive ability. Validated biomarkers would be of great value in support of a diagnosis, as well as in natural history studies and in the development of new therapeutics in this population.
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[In Context] Capturing the agony and humour of dementia
One of the most unsettling aspects of a family member or other loved one developing dementia is how they can physically appear exactly the same on the outside, yet transform beyond all recognition on the inside as their mind disintegrates, their memory evaporates, and their personality changes. That dissonance between body and mind was captured perfectly by All Change, a one-act play staged by Smokescreen Productions at the Edinburgh Festival Fringe, the world's largest arts festival. All Change was written by Toby Marriott during an emerging writers' course at the Bristol Old Vic Theatre (Bristol, UK), and was developed as a play with five actors through performances at Eastbourne College (Eastbourne, UK), The Alma in Bristol, and the Brighton Fringe Festival (Brighton, UK).
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[In Context] Exploring memories of Rasputin, the Queen, and police interviews
In an age of social media networks like Instagram, Twitter, and Facebook, it sometimes feels like the photograph is king. Holidays, meals, and key moments in people's lives are snapped, uploaded, and liked, while the cult of the "selfie" appears to be becoming pervasive. Photographs can sometimes seem to be the ultimate record of a life, whether they're posted on a website or kept in a traditional album on a shelf. Yet, as one of the characters in Everything Not Saved, a show at the Edinburgh Festival Fringe in the UK, points out: "Photos aren't actually memories." While a photograph can only capture a single perspective of a single moment in time, a memory can change over the years.
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