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donderdag 27 september 2018

Nature Reviews Gastroenterology & Hepatology - Table of Contents alert Volume 15 Issue 10

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Nature Reviews Gastroenterology & Hepatology

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TABLE OF CONTENTS

October 2018 Volume 15, Issue 10

Research Highlights
News & Views
Reviews
 

Research Highlights

 
Exploring human gastric cancers through organoid culture
Hugh Thomas

p581 | doi:10.1038/s41575-018-0066-x
PDF


 
Immunotherapy-responsive gastric cancers identified
Peter Sidaway

p582 | doi:10.1038/s41575-018-0063-0
PDF


 
Senescence prevents regeneration after acute liver injury
Hugh Thomas

p582 | doi:10.1038/s41575-018-0068-8
PDF


 
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News & Views

 
T cells in coeliac disease: a rational target for diagnosis and therapy
Melinda Y. Hardy & Jason A. Tye-Din

pp583 - 584 | doi:10.1038/s41575-018-0043-4
PDF


 
Gut microbiota as gatekeeper of anti-tumour responses in the liver
Timon E. Adolph & Herbert Tilg

pp584 - 586 | doi:10.1038/s41575-018-0046-1
PDF


 
Organoidomics — falling star or new galaxy in pancreatic cancer?
Thomas Seufferlein & Alexander Kleger

pp586 - 587 | doi:10.1038/s41575-018-0052-3
PDF


 

Reviews

 
New treatments and therapeutic targets for IBS and other functional bowel disorders   
Magnus Simrén & Jan Tack

pp589 - 605 | doi:10.1038/s41575-018-0034-5
Current effective treatment options for IBS and other functional bowel disorders are limited. This Review focuses on new and emerging therapies that target the entire symptom complex in these common disorders.
Full Text | PDF


 
Gut adaptation after metabolic surgery and its influences on the brain, liver and cancer   
Piriyah Sinclair, Donal J. Brennan & Carel W. le Roux

pp606 - 624 | doi:10.1038/s41575-018-0057-y
Metabolic surgery is the best treatment for long-term weight loss maintenance and comorbidity control. In this Review, the authors discuss how gut physiology adapts to these procedures and the consequent effects on food intake, weight loss, liver disease and cancer.
Full Text | PDF


 
The metabolic role of vagal afferent innervation   
T. M. Zaved Waise, Helen J. Dranse & Tony K. T. Lam

pp625 - 636 | doi:10.1038/s41575-018-0062-1
Metabolic homeostasis is orchestrated partly in response to nutrient-dependent vagal afferent signals transmitted from the gut to the central nervous system. This Review highlights our understanding of the vagal afferent system and its role in regulation of appetite and glucose homeostasis.
Full Text | PDF


 
The elusive case of human intraepithelial T cells in gut homeostasis and inflammation   
Lisanne Lutter, David P. Hoytema van Konijnenburg, Eelco C. Brand, Bas Oldenburg & Femke van Wijk

pp637 - 649 | doi:10.1038/s41575-018-0039-0
Intraepithelial T cells (IETs) are a unique collection of T cells located at the epithelial barrier. This Review highlights the role of these cells in gut homeostasis and disease, including coeliac disease and IBD. Targeting of IETs in therapeutic interventions is also discussed.
Full Text | PDF


 
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