We bring you the latest news from the healthcare about the health care in the United Kingdom.

donderdag 9 augustus 2018

The Lancet: [Comment] The Lancet–EASL Commission on liver diseases in Europe: overcoming unmet needs, stigma, and i...

[Comment] The Lancet–EASL Commission on liver diseases in Europe: overcoming unmet needs, stigma, and inequities
Worldwide, liver diseases are on the rise. As an example, death rates from viral hepatitis now outnumber those from HIV/AIDS.1 The Lancet Commission on liver disease in the UK provided evidence that standardised UK mortality attributable to liver diseases has risen four-fold between 1980 and 2013,2 with liver disease likely to overtake ischaemic heart disease as the leading cause of years of working life lost.3 In addition to varying trends in mortality (figure),4,5 there are substantial differences in how the management of patients is organised within health systems.
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[Correspondence] Ebola Medals returned to the UK Government in protest
The UK's hostile environment policies are being increasingly challenged, but within health care, charging regulations in the National Health Service (NHS) remain unchanged, and many migrants continue to fear seeking help when unwell. The October, 2017, amendments to these regulations brought in upfront charging, at 150% of the actual cost, before treatment, to anybody unable to prove their immigration status. This is applied to secondary care and various community services, and even pregnant women and children are charged.
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[Seminar] Acute myeloid leukaemia
For several decades, few substantial therapeutic advances have been made for patients with acute myeloid leukaemia. However, since 2017 unprecedented growth has been seen in the number of drugs available for the treatment of acute myeloid leukaemia, with several new drugs receiving regulatory approval. In addition to advancing our therapeutic armamentarium, an increased understanding of the biology and genomic architecture of acute myeloid leukaemia has led to refined risk assessment of this disease, with consensus risk stratification guidelines now incorporating a growing number of recurrent molecular aberrations that aid in the selection of risk-adapted management strategies.
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[Seminar] Autism spectrum disorder
Autism spectrum disorder is a term used to describe a constellation of early-appearing social communication deficits and repetitive sensory–motor behaviours associated with a strong genetic component as well as other causes. The outlook for many individuals with autism spectrum disorder today is brighter than it was 50 years ago; more people with the condition are able to speak, read, and live in the community rather than in institutions, and some will be largely free from symptoms of the disorder by adulthood.
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[Articles] Efficacy and safety of risankizumab in moderate-to-severe plaque psoriasis (UltIMMa-1 and UltIMMa-2): results from two double-blind, randomised, placebo-controlled and ustekinumab-controlled phase 3 trials
Risankizumab showed superior efficacy to both placebo and ustekinumab in the treatment of moderate-to-severe plaque psoriasis. Treatment-emergent adverse event profiles were similar across treatment groups and there were no unexpected safety findings.
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