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vrijdag 29 juni 2018

Nature Reviews Neurology - Table of Contents alert Volume 14 Issue 7

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Nature Reviews Neurology

July 2018 Volume 14, Issue 7

Research Highlights
News & Views
Amendments & Corrections

Managing Neuropsychiatric Symptoms in Neurodegenerative Disease June 14, 2018, NYC

Featuring Jeff Cummings, MD, of the Cleveland Clinic, this symposium will review current methods in the diagnosis and management of psychiatric symptoms in neurodegenerative diseases and discuss strategies to reduce the societal costs associated with these symptoms. Webinar available. Register today

Research Highlights


Positive trials in ischaemic stroke reported at ESOC 2018    p379
Ian Fyfe

Tau seeding starts early in the entorhinal cortex    p380
Charlotte Ridler

New biomarker predicts disability in MS    p380
Charlotte Ridler

Deep brain stimulation boosts motor connectivity    p380
Charlotte Ridler

Selective neuronal loss could limit penumbral rescue after stroke    pp380 - 381
Heather Wood

Drop seizures cut by cannabidiol    pp380 - 381
Charlotte Ridler

Placental gene expression linked to schizophrenia risk    p381
Heather Wood

Nature Reviews Neurology
JOBS of the week
Postdoctoral Research Fellowship- Drug Addiction / Cognitive Neuroscience
National Institute on Drug Abuse (NIDA)
Postdoctoral research fellowship in Chemical Neuroscience
University of Oslo
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Nature Reviews Neurology
The 13th World Congress on Controversies in Neurology (CONy) 2019
Madrid, Spain
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News & Views


Improved grading of IDH-mutated astrocytic gliomas    pp383 - 384
Christopher J. Pirozzi & Hai Yan

AAN unveils new guidelines for MS disease-modifying therapy    pp384 - 386
Stefan Bittner & Frauke Zipp

Do you have a career question? 

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Cerebral small vessel disease: from a focal to a global perspective    pp387 - 398
Annemieke ter Telgte, Esther M. C. van Leijsen, Kim Wiegertjes, Catharina J. M. Klijn, Anil M. Tuladhar et al.

Cerebral small vessel disease (SVD) is associated with highly heterogeneous clinical symptoms. This Review considers how new advances in structural and functional neuroimaging have revealed ways in which focal lesions can affect remote brain regions and lead to global dysfunction, resulting in the variable presentation of SVD.


Tau-targeting therapies for Alzheimer disease    pp399 - 415
Erin E. Congdon & Einar M. Sigurdsson

Interest in tau-targeting strategies for Alzheimer disease is increasing, in part because of the failure of various amyloid-β-targeting treatments in clinical trials. Congdon and Sigurdsson review the current status of tau-targeting therapies, including anti-tau drugs and immunotherapies.


Haemoglobin scavenging in intracranial bleeding: biology and clinical implications    pp416 - 432
Diederik Bulters, Ben Gaastra, Ardalan Zolnourian, Sheila Alexander, Dianxu Ren et al.

Free haemoglobin released from red blood cells after intracranial bleeding can lead to neurotoxicity and exacerbate injury. In this Review, the authors consider the biology behind haemoglobin toxicity and the clinical potential of targeting haemoglobin scavenging systems to aid recovery.


Neuroimmune disorders of the central nervous system in children in the molecular era    pp433 - 445
Elizabeth Wells, Yael Hacohen, Amy Waldman, Jan M. Tillema, Ariane Soldatos et al.

In this Review, the authors discuss all aspects of immune-mediated disorders of the CNS in children, from the clinical features and treatment to pathological mechanisms and biomarkers, and outline priorities for collaborative research to develop precision medicine for these disorders.


Amendments & Corrections


Author Correction: Imaging tau and amyloid-β proteinopathies in Alzheimer disease and other conditions    p446


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