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vrijdag 29 juni 2018

Nature Reviews Neurology - Table of Contents alert Volume 14 Issue 7

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Nature Reviews Neurology
TABLE OF CONTENTS

July 2018 Volume 14, Issue 7

Research Highlights
News & Views
Reviews
Amendments & Corrections
 

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Research Highlights

 

Positive trials in ischaemic stroke reported at ESOC 2018    p379
Ian Fyfe
doi:10.1038/s41582-018-0023-x

Tau seeding starts early in the entorhinal cortex    p380
Charlotte Ridler
doi:10.1038/s41582-018-0016-9

New biomarker predicts disability in MS    p380
Charlotte Ridler
doi:10.1038/s41582-018-0017-8

Deep brain stimulation boosts motor connectivity    p380
Charlotte Ridler
doi:10.1038/s41582-018-0018-7

Selective neuronal loss could limit penumbral rescue after stroke    pp380 - 381
Heather Wood
doi:10.1038/s41582-018-0015-x

Drop seizures cut by cannabidiol    pp380 - 381
Charlotte Ridler
doi:10.1038/s41582-018-0022-y

Placental gene expression linked to schizophrenia risk    p381
Heather Wood
doi:10.1038/s41582-018-0027-6

Nature Reviews Neurology
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News & Views

 

Improved grading of IDH-mutated astrocytic gliomas    pp383 - 384
Christopher J. Pirozzi & Hai Yan
doi:10.1038/s41582-018-0019-6

AAN unveils new guidelines for MS disease-modifying therapy    pp384 - 386
Stefan Bittner & Frauke Zipp
doi:10.1038/s41582-018-0026-7

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Reviews

 

Cerebral small vessel disease: from a focal to a global perspective    pp387 - 398
Annemieke ter Telgte, Esther M. C. van Leijsen, Kim Wiegertjes, Catharina J. M. Klijn, Anil M. Tuladhar et al.
doi:10.1038/s41582-018-0014-y

Cerebral small vessel disease (SVD) is associated with highly heterogeneous clinical symptoms. This Review considers how new advances in structural and functional neuroimaging have revealed ways in which focal lesions can affect remote brain regions and lead to global dysfunction, resulting in the variable presentation of SVD.

 

Tau-targeting therapies for Alzheimer disease    pp399 - 415
Erin E. Congdon & Einar M. Sigurdsson
doi:10.1038/s41582-018-0013-z

Interest in tau-targeting strategies for Alzheimer disease is increasing, in part because of the failure of various amyloid-β-targeting treatments in clinical trials. Congdon and Sigurdsson review the current status of tau-targeting therapies, including anti-tau drugs and immunotherapies.

 

Haemoglobin scavenging in intracranial bleeding: biology and clinical implications    pp416 - 432
Diederik Bulters, Ben Gaastra, Ardalan Zolnourian, Sheila Alexander, Dianxu Ren et al.
doi:10.1038/s41582-018-0020-0

Free haemoglobin released from red blood cells after intracranial bleeding can lead to neurotoxicity and exacerbate injury. In this Review, the authors consider the biology behind haemoglobin toxicity and the clinical potential of targeting haemoglobin scavenging systems to aid recovery.

 

Neuroimmune disorders of the central nervous system in children in the molecular era    pp433 - 445
Elizabeth Wells, Yael Hacohen, Amy Waldman, Jan M. Tillema, Ariane Soldatos et al.
doi:10.1038/s41582-018-0024-9

In this Review, the authors discuss all aspects of immune-mediated disorders of the CNS in children, from the clinical features and treatment to pathological mechanisms and biomarkers, and outline priorities for collaborative research to develop precision medicine for these disorders.

 

Amendments & Corrections

 

Author Correction: Imaging tau and amyloid-β proteinopathies in Alzheimer disease and other conditions    p446

doi:10.1038/s41582-018-0021-z

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