We bring you the latest news from the healthcare about the health care in the United Kingdom.

woensdag 16 mei 2018

The Lancet: [In Context] Out of the ring: boxing and long-term brain damage

[In Context] Out of the ring: boxing and long-term brain damage
It is May 2, 2015, and the boxing world is psyched for the bout billed as the "Fight of the Century" between Floyd Mayweather and Manny Pacquiao. It turned out to be a disappointing match for viewers, but the total revenue generated was far from unsatisfactory. It earned over US$400 million with 4·6 million pay-per-view buys, and the boxers agreed a 60/40 split for the $300 million prize. Back in June 1997, the infamous ear-biting fight between Mike Tyson and Evander Holyfield generated US$100 million, Tyson taking home US$30 million and Holyfield US$35 million.
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[In Context] William Alexander Hammond
Neurological pioneer and co-founder of the American Neurological Association. Born in Annapolis, MD, USA, on Aug 28, 1828, he died on Jan 5, 1900, in Washington, DC, USA.
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[In Context] For the love of Piltdown Man
Which work of art best symbolises the 20th century? Some might name Marcel Duchamp's Nude Descending a Staircase, No. 2, whose fractured perspectives illustrate the transition from a world of absolute rationality to one of relativity. Das Undbild, a collage assembled by Kurt Schwitters from discarded ephemera, poignantly captures the transitory and fragmented nature of modern life; Picasso's Guernica mirrors our humanity, passion, and horror. But my favourite work of 20th century art is Piltdown Man: it shows us who we are, and what we dream of becoming.
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[In Context] Martin Dichgans: opening the doors of discovery
Genes can be a doorway to understanding the basis of disease. One neurologist who had the foresight to knock on this door is Martin Dichgans, Professor of Neurology (Institute for Stroke and Dementia Research [ISD], Munich, Germany): "genetics provide you with a starting point that is unquestionably relevant, can lead you to novel targets for intervention, and save you from focusing on confounding factors instead of the disease itself."
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[Articles] Cerebral microbleeds and intracranial haemorrhage risk in patients anticoagulated for atrial fibrillation after acute ischaemic stroke or transient ischaemic attack (CROMIS-2): a multicentre observational cohort study
In patients with atrial fibrillation anticoagulated after recent ischaemic stroke or transient ischaemic attack, cerebral microbleed presence is independently associated with symptomatic intracranial haemorrhage risk and could be used to inform anticoagulation decisions. Large-scale collaborative observational cohort analyses are needed to refine and validate intracranial haemorrhage risk scores incorporating cerebral microbleeds to identify patients at risk of net harm from oral anticoagulation.
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