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dinsdag 29 mei 2018

The Lancet: [Articles] Prevalence of abdominal cystic echinococcosis in rural Bulgaria, Romania, and Turkey: a cross-...

[Articles] Prevalence of abdominal cystic echinococcosis in rural Bulgaria, Romania, and Turkey: a cross-sectional, ultrasound-based, population study from the HERACLES project
Our results provide population-based estimates of the prevalence of abdominal cystic echinococcosis. These findings should be useful to support the planning of cost-effective interventions, supporting the WHO roadmap for cystic echinococcosis control.
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[Comment] Eliminating cystic echinococcosis in the 21st century
Cystic echinococcosis is a helminthic disease caused by the larval stage of the cestode Echinococcus granulosus. This parasitic disease is regarded as a zoonosis because adult worms and eggs are found in the small intestine of carnivores, whereas the larval stage infects humans. As a definitive host, dogs play a major part in transmitting the infection to humans: tapeworms pass proglottids and eggs in dogs' faeces and humans become infected through faecal-oral contact. The presence of a cyst-like mass in a person with a history of exposure to dogs in areas where E granulosus is endemic supports the diagnosis of cystic echinococcosis.
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[Corrections] Corrections
Burki T. David Cooper. Lancet Infect Dis 2018; 18: 505—Prof Cooper's mother Annie was born in Leeds, UK; her parents were from Lithuania. The correction has been made to the online version as of May 25, 2018.
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[Comment] The resurgence of scarlet fever in China
Scarlet fever, a common infectious disease in children caused by group A streptococcus, was a major cause of death before the early 20th century.1 With the widespread use of antibiotics, its incidence and mortality have substantially reduced. However, studies from the past decade have shown a resurgence of the disease in Hong Kong, South Korea, and the UK.2–4 In The Lancet Infectious Diseases, Yonghong Liu and colleagues5 describe the rise in the incidence of scarlet fever in China since 2011 by use of data from the National Notifiable Infectious Disease Surveillance System of China.
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[Articles] Efficacy and tolerability of moxidectin alone and in co-administration with albendazole and tribendimidine versus albendazole plus oxantel pamoate against Trichuris trichiura infections: a randomised, non-inferiority, single-blind trial
Moxidectin plus albendazole showed non-inferiority to albendazole plus oxantel pamoate in terms of ERR; however, albendazole plus oxantel pamoate showed a considerably higher cure rate. Dose-optimisation studies with moxidectin and moxidectin plus albendazole should be considered since the efficacy of the dose used for the treatment of onchocerciasis (8 mg) in this study might not be optimal for the treatment of T trichiura infections.
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