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dinsdag 17 april 2018

Nature Reviews Neuroscience contents May 2018 Volume 19 Number 5 pp 251-316

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Nature Reviews Neuroscience
May 2018 Volume 19 Number 5 Advertisement
Nature Reviews Neuroscience cover
2016 2-year Impact Factor 28.880 Journal Metrics 2-year Median 23
In this issue
Research Highlights
Also this month
Featured article:
Food intake, metabolism and the brain
 Featured article:
Cortical travelling waves: mechanisms and computational principles
Lyle Muller, Frédéric Chavane, John Reynolds & Terrence J. Sejnowski

Adolescence Collection

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Alzheimer's research grants -- awards up to $600,000

Alzheimer's Drug Discovery Foundation and Harrington Discovery Institute announce the 2018 ADDF-Harrington Scholar Award, supporting research efforts that seek to treat, prevent, slow, or cure Alzheimer's disease and related conditions.

Letters of Intent accepted through May 25, 2018. Apply at HarringtonDiscovery.org/ADDF.

Neural repair: Getting back on your hindlimbs
p251 | doi:10.1038/nrn.2018.39
A combination of electrochemical neuromodulation of spinal leg circuits and physical training in a robotic rehabilitation system restored volitional locomotion in rodents with severe spinal cord injury.


Spinal cord: Making new connections
p252 | doi:10.1038/nrn.2018.33
This study shows that human neural stem cell grafts re-establish a neuronal relay across spinal cord injury in rhesus monkeys.


Neurogenesis: News of no new neurons?
p252 | doi:10.1038/nrn.2018.34
A study of post-mortem brains from individuals of difference ages suggests that hippocampal neurogenesis in humans decreases during childhood and is absent in adults.


Neural development: Instigating engulfment
p253 | doi:10.1038/nrn.2018.31
In the spinal cord and thalamus of mice, astrocyte-generated interleukin-33 instructs microglia to engulf synapses and thus regulates neural circuit development.


Neural circuits: Balancing threats
p254 | doi:10.1038/nrn.2018.35
Two studies provide insight into the neural circuits integrating competing threat signals, such as pain and hunger.




Myelin: Wrapped up | Techniques: In a split sequence | Techniques: MEG in motion

Nature Reviews Neuroscience
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Cortical travelling waves: mechanisms and computational principles
Lyle Muller, Frédéric Chavane, John Reynolds & Terrence J. Sejnowski

p255 | doi:10.1038/nrn.2018.20
Advanced recording techniques have enabled the identification of travelling waves of neuronal activity in different areas of the cortex. Sejnowski and colleagues review these findings, consider the mechanisms by which travelling waves are generated and evaluate their possible roles in cortical function.
Abstract | Full Text | PDF

Surviving threats: neural circuit and computational implications of a new taxonomy of defensive behaviour
Joseph LeDoux & Nathaniel D. Daw

p269 | doi:10.1038/nrn.2018.22
Animals exhibit a variety of different responses to threatening stimuli, including both innate and instrumental behaviours. LeDoux and Daw describe a new taxonomy of defensive behaviours and review what we know about the underlying neural circuits and computational processes.
Abstract | Full Text | PDF

Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics
Mark A. Petersen, Jae Kyu Ryu & Katerina Akassoglou

p283 | doi:10.1038/nrn.2018.13
Fibrinogen enters the brain in a wide range of brain diseases that involve blood-brain barrier disruption. In this Review, Petersen et al. discuss recent evidence that fibrinogen causes damage that contributes to the pathology of a range of neurological disorders and discuss therapeutic implications.
Abstract | Full Text | PDF

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Article series: Food intake, metabolism and the brain
Feeding circuit development and early-life influences on future feeding behaviour
Lori M. Zeltser

p302 | doi:10.1038/nrn.2018.23
The extent and contribution of maternal influence to the developing hypothalamus to later feeding behaviour remain controversial. In this Opinion, Zeltser proposes that crosstalk between developing circuits regulating different modalities of food intake shapes susceptibility to environmental challenges.
Abstract | Full Text | PDF

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