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donderdag 26 april 2018

Nature Reviews Neurology - Table of Contents alert Volume 14 Issue 5

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Nature Reviews Neurology
 

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TABLE OF CONTENTS
 
May 2018 Volume 14 Number 5  
Nature Reviews Neurology cover
2016 2-year Impact Factor 20.257 Journal Metrics 2-year Median 15
In this issue
Research Highlights
News and Views
Reviews
 
Also this month
 Featured article:
Physiological changes in neurodegeneration — mechanistic insights and clinical utility
Rebekah M. Ahmed, Yazi D. Ke, Steve Vucic, Lars M. Ittner, William Seeley, John R. Hodges, Olivier Piguet, Glenda Halliday & Matthew C. Kiernan

 
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RESEARCH HIGHLIGHTS
 
Top

Epilepsy: A role for expanded DNA repeats in familial epilepsy
Published online: 23 March 2018
p251 | doi:10.1038/nrneurol.2018.37

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Gene therapy: Gene therapy targets pathology in progranulin-deficient mice
Published online: 16 March 2018
p252 | doi:10.1038/nrneurol.2018.35

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Stroke: An alarmin' inflammatory response after stroke
Published online: 03 April 2018
p252 | doi:10.1038/nrneurol.2018.40

PDF


Motor neuron disease: Reactive microglia protect neurons in ALS
Published online: 09 March 2018
p253 | doi:10.1038/nrneurol.2018.28

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Traumatic brain injury: Evidence of blood-brain barrier disruption after concussion
Published online: 09 March 2018
p254 | doi:10.1038/nrneurol.2018.29

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Alzheimer disease: Epigenetics links ageing with Alzheimer disease
Published online: 23 March 2018
p254 | doi:10.1038/nrneurol.2018.36

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IN BRIEF

Spinal cord injury: Human neural stem cells elicit regeneration after spinal cord injury in monkeys | Parkinson disease: Truncated α-synuclein causes mitochondrial toxicity | Prion disease: Dramatic increases in blood levels of tau and neurofilament light in patients with prion disease
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NEWS AND VIEWS
 
Top
Neuroimmunology: Are naturally occurring anti-NMDAR autoantibodies pathogenic?
Keiko Tanaka

Published online: 03 April 2018
p255 | doi:10.1038/nrneurol.2018.41

Autoantibodies against the N-methyl-d-aspartate receptor (NMDAR) are known to cause encephalitis; however, a new study has identified anti-NMDAR antibodies in the absence of encephalitis in various mammalian species. These chronically produced natural antibodies might function in physiological target protein modulation and contribute to the symptoms of non-immune diseases.
Full Text | PDF

 
Epilepsy: Timely treatment of refractory convulsive status epilepticus
Alberto Verrotti & Chiara Mazzocchetti

Published online: 23 March 2018
p256 | doi:10.1038/nrneurol.2018.38

Delayed treatment of status epilepticus is known to increase seizure duration, but new research shows that a delay of more than 10 minutes from seizure onset increases morbidity and risk of death. The findings emphasize the importance of time and suggest that status epilepticus should be treated as a medical emergency.
Full Text | PDF

 
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REVIEWS
 
Top
Physiological changes in neurodegeneration — mechanistic insights and clinical utility
Rebekah M. Ahmed et al.

Published online: 23 March 2018
p259 | doi:10.1038/nrneurol.2018.23

In this Review, Ahmed et al. look at the changes in physiological function that occur in neurodegenerative syndromes, consider the similarities and differences in these changes across conditions, and discuss the clinical utility of detecting these changes.
Abstract | Full Text | PDF

 
Complex regional pain syndrome — phenotypic characteristics and potential biomarkers
Frank Birklein et al.

Published online: 16 March 2018
p272 | doi:10.1038/nrneurol.2018.20

Complex regional pain syndrome (CRPS) is a persistent pain condition that usually affects a single limb, often following an injury. In this article, the authors review the latest advances in CRPS research, focusing on risk factors for the condition as well as biomarkers for diagnosis, treatment and clinical course prediction.
Abstract | Full Text | PDF

 
Teleneurology and mobile technologies: the future of neurological care
E. Ray Dorsey et al.

Published online: 06 April 2018
p285 | doi:10.1038/nrneurol.2018.31

Globally, access to neurological care remains limited for many people. However, technologies such as smart phones are now facilitating unprecedented access to remote care and specialist expertise. Here, Dorsey and colleagues discuss evidence of the benefits and risks of teleneurology for chronic disorders, including Parkinson disease, epilepsy and multiple sclerosis, as well as future trends and barriers to adoption.
Abstract | Full Text | PDF

 
Japanese encephalitis — the prospects for new treatments
Lance Turtle & Tom Solomon

Published online: 26 April 2018
p298 | doi:10.1038/nrneurol.2018.30

Japanese encephalitis remains the most commonly diagnosed epidemic encephalitis in the world despite the availability of vaccines, and new therapeutic strategies are sorely needed. Here, Turtle and Solomon summarize the epidemiology, clinical features, prevention and treatment of Japanese encephalitis and discuss the emerging challenges and opportunities for tackling the disease in humans.
Abstract | Full Text | PDF

 
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Corrigendum: PET imaging of the neurovascular interface in cerebrovascular disease
Nicholas R. Evans et al.

Published online: 03 April 2018
p313 | doi:10.1038/nrneurol.2018.42

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Nature Reviews Neurology was previously published as Nature Clinical Practice Neurology.
 

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