We bring you the latest news from the healthcare about the health care in the United Kingdom.

donderdag 26 april 2018

Nature Reviews Neurology - Table of Contents alert Volume 14 Issue 5

If you are unable to see the message below, click here to view.
Nature Reviews Neurology

nature.com webcasts

Nature Research Custom presents a webcast on: MicroRNAs in CSF as prodromal biomarkers for Huntington's disease

Date: Tuesday, May 29, 2018

Join our webcast to learn about the fundamental characteristics of microRNAs and why Huntington's disease may serve as a disease model for the assessment of biomarkers.

This webcast has been produced on behalf of the sponsor who retains sole responsibility for content 

Register for FREE 

Sponsored by: HTG Molecular 
May 2018 Volume 14 Number 5  
Nature Reviews Neurology cover
2016 2-year Impact Factor 20.257 Journal Metrics 2-year Median 15
In this issue
Research Highlights
News and Views
Also this month
 Featured article:
Physiological changes in neurodegeneration — mechanistic insights and clinical utility
Rebekah M. Ahmed, Yazi D. Ke, Steve Vucic, Lars M. Ittner, William Seeley, John R. Hodges, Olivier Piguet, Glenda Halliday & Matthew C. Kiernan

Recommend to library
Nature Milestone: Anticoagulants from Nature Reviews Cardiology 

This Milestone plots the history of anticoagulant drugs, used to prevent and treat thrombotic disorders in millions of patients worldwide. Fourteen Milestone articles are presented on an interactive timeline with associated multimedia. 

Access free online 

Produced with support from Portola Pharmaceuticals, Inc. 

Epilepsy: A role for expanded DNA repeats in familial epilepsy
Published online: 23 March 2018
p251 | doi:10.1038/nrneurol.2018.37


Gene therapy: Gene therapy targets pathology in progranulin-deficient mice
Published online: 16 March 2018
p252 | doi:10.1038/nrneurol.2018.35


Stroke: An alarmin' inflammatory response after stroke
Published online: 03 April 2018
p252 | doi:10.1038/nrneurol.2018.40


Motor neuron disease: Reactive microglia protect neurons in ALS
Published online: 09 March 2018
p253 | doi:10.1038/nrneurol.2018.28


Traumatic brain injury: Evidence of blood-brain barrier disruption after concussion
Published online: 09 March 2018
p254 | doi:10.1038/nrneurol.2018.29


Alzheimer disease: Epigenetics links ageing with Alzheimer disease
Published online: 23 March 2018
p254 | doi:10.1038/nrneurol.2018.36




Spinal cord injury: Human neural stem cells elicit regeneration after spinal cord injury in monkeys | Parkinson disease: Truncated α-synuclein causes mitochondrial toxicity | Prion disease: Dramatic increases in blood levels of tau and neurofilament light in patients with prion disease

International Conference on Neurology and brain Disorders
Rome, Italy
More science events from
Neuroimmunology: Are naturally occurring anti-NMDAR autoantibodies pathogenic?
Keiko Tanaka

Published online: 03 April 2018
p255 | doi:10.1038/nrneurol.2018.41

Autoantibodies against the N-methyl-d-aspartate receptor (NMDAR) are known to cause encephalitis; however, a new study has identified anti-NMDAR antibodies in the absence of encephalitis in various mammalian species. These chronically produced natural antibodies might function in physiological target protein modulation and contribute to the symptoms of non-immune diseases.
Full Text | PDF

Epilepsy: Timely treatment of refractory convulsive status epilepticus
Alberto Verrotti & Chiara Mazzocchetti

Published online: 23 March 2018
p256 | doi:10.1038/nrneurol.2018.38

Delayed treatment of status epilepticus is known to increase seizure duration, but new research shows that a delay of more than 10 minutes from seizure onset increases morbidity and risk of death. The findings emphasize the importance of time and suggest that status epilepticus should be treated as a medical emergency.
Full Text | PDF

Do you have a career question? 

The Naturejobs podcast features one-on-one Q&As, panel discussions and other exclusive content to help scientists with their careers. Hosted on the Naturejobs blog, the podcast is also available on iTunes and Soundcloud. 

Listen today!
Physiological changes in neurodegeneration — mechanistic insights and clinical utility
Rebekah M. Ahmed et al.

Published online: 23 March 2018
p259 | doi:10.1038/nrneurol.2018.23

In this Review, Ahmed et al. look at the changes in physiological function that occur in neurodegenerative syndromes, consider the similarities and differences in these changes across conditions, and discuss the clinical utility of detecting these changes.
Abstract | Full Text | PDF

Complex regional pain syndrome — phenotypic characteristics and potential biomarkers
Frank Birklein et al.

Published online: 16 March 2018
p272 | doi:10.1038/nrneurol.2018.20

Complex regional pain syndrome (CRPS) is a persistent pain condition that usually affects a single limb, often following an injury. In this article, the authors review the latest advances in CRPS research, focusing on risk factors for the condition as well as biomarkers for diagnosis, treatment and clinical course prediction.
Abstract | Full Text | PDF

Teleneurology and mobile technologies: the future of neurological care
E. Ray Dorsey et al.

Published online: 06 April 2018
p285 | doi:10.1038/nrneurol.2018.31

Globally, access to neurological care remains limited for many people. However, technologies such as smart phones are now facilitating unprecedented access to remote care and specialist expertise. Here, Dorsey and colleagues discuss evidence of the benefits and risks of teleneurology for chronic disorders, including Parkinson disease, epilepsy and multiple sclerosis, as well as future trends and barriers to adoption.
Abstract | Full Text | PDF

Japanese encephalitis — the prospects for new treatments
Lance Turtle & Tom Solomon

Published online: 26 April 2018
p298 | doi:10.1038/nrneurol.2018.30

Japanese encephalitis remains the most commonly diagnosed epidemic encephalitis in the world despite the availability of vaccines, and new therapeutic strategies are sorely needed. Here, Turtle and Solomon summarize the epidemiology, clinical features, prevention and treatment of Japanese encephalitis and discuss the emerging challenges and opportunities for tackling the disease in humans.
Abstract | Full Text | PDF

Searching for a new career?

At Nature Research we frequently recruit talented individuals to join our editorial and publishing teams. If you have a PhD and a passion for science this may be the perfect career for you.

Visit our research editorial and publishing careers website to discover more about what we do
Corrigendum: PET imaging of the neurovascular interface in cerebrovascular disease
Nicholas R. Evans et al.

Published online: 03 April 2018
p313 | doi:10.1038/nrneurol.2018.42

Full Text | PDF
nature events
Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here.

Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com
More Nature Events
Nature Reviews Neurology was previously published as Nature Clinical Practice Neurology.

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/myaccount
(You will need to log in to be recognised as a nature.com registrant).

For further technical assistance, please contact our registration department

For print subscription enquiries, please contact our subscription department

For other enquiries, please contact our feedback department

Springer Nature | One New York Plaza, Suite 4500 | New York | NY 10004-1562 | USA

Springer Nature's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne
San Diego - San Francisco - Washington - New York - Boston

Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at The Campus, 4 Crinan Street, London, N1 9XW.

© 2018 Macmillan Publishers Limited, part of Springer Nature. All Rights Reserved.

Springer Nature