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dinsdag 10 april 2018

Nature Reviews Endocrinology - Table of Contents alert Volume 14 Issue 5

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Nature Reviews Endocrinology

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May 2018 Volume 14 Number 5
Nature Reviews Endocrinology cover
2016 2-year Impact Factor 18.318
Journal Metrics 2-year Median 13
In this issue
Research Highlights
News and Views
Also this month
 Featured article:
Direct effects of thyroid hormones on hepatic lipid metabolism
Rohit A. Sinha, Brijesh K. Singh & Paul M. Yen

Recommend to library

Obesity: ANGPTL4 — the link binding obesity and glucose intolerance
Published online: 03 April 2018
p251 | doi:10.1038/nrendo.2018.35


Diabetes: LRP1 — a key modulator of β-cell function in T2DM
Published online: 09 March 2018
p252 | doi:10.1038/nrendo.2018.30


Metabolism: DRP1 links mitochondrial dynamics to the clock
Published online: 09 March 2018
p252 | doi:10.1038/nrendo.2018.32


Obesity: ERAD linked to obesity
Published online: 09 March 2018
p253 | doi:10.1038/nrendo.2018.29


Exercise: Wearable activity trackers in cardiovascular research
Published online: 16 March 2018
p253 | doi:10.1038/nrendo.2018.33


PCOS: Metformin risk for offspring
Published online: 16 March 2018
p253 | doi:10.1038/nrendo.2018.34



Bone: Bone marrow adipocytes in 3D
Kenneth T. Lewis & Ormond A. MacDougald

Published online: 16 March 2018
p254 | doi:10.1038/nrendo.2018.31

Culturing bone marrow stromal cells on 3D silk scaffolds supports their proliferation and adipogenesis, while minimizing the activation of inflammatory pathways. Therefore, differentiation of bone marrow adipocytes in 3D culture might provide a more representative model for the study of bone marrow adipose tissue than is offered by traditional 2D cell cultures.
Full Text | PDF

Bone: Microarchitecture of bone predicts fractures in older women
Richard Eastell & Jennifer S. Walsh

Published online: 09 March 2018
p255 | doi:10.1038/nrendo.2018.27

High-resolution peripheral quantitative CT (HRpQCT) provides more detailed information than older methods. A new study shows that radial and tibial HRpQCT measurements are associated with incident fracture in postmenopausal women. However, it is unclear whether HRpQCT improves fracture risk prediction enough to justify its use in clinical practice.
Full Text | PDF

Surgery: The new gold-standard — medical gastric bypass
Alexander D. Miras & Carel W. le Roux

Published online: 16 March 2018
p257 | doi:10.1038/nrendo.2018.28

A recent randomized controlled clinical trial with 5-year follow-up demonstrates the impressive effectiveness of the combination of metabolic surgery with medical therapies and shifts the paradigm in the care of patients with obesity and type 2 diabetes mellitus.
Full Text | PDF

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Direct effects of thyroid hormones on hepatic lipid metabolism
Rohit A. Sinha, Brijesh K. Singh & Paul M. Yen

Published online: 23 February 2018
p259 | doi:10.1038/nrendo.2018.10

Thyroid hormones can affect hepatic fatty acid metabolism and cholesterol synthesis. Here, Paul Yen and colleagues describe and summarize the key features of direct thyroid hormone regulation of lipogenesis, fatty acid β-oxidation, cholesterol synthesis and the reverse cholesterol transport pathway in normal and altered thyroid states.
Abstract | Full Text | PDF

Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment
Hector F. Escobar-Morreale

Published online: 23 March 2018
p270 | doi:10.1038/nrendo.2018.24

Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in premenopausal women. Here, Hector F. Escobar-Morreale reviews the newest advances and limitations of current knowledge regarding PCOS and provides principles for the diagnosis and management of women with PCOS.
Abstract | Full Text | PDF

Growth hormone — past, present and future
Michael B. Ranke & Jan M. Wit

Published online: 16 March 2018
p285 | doi:10.1038/nrendo.2018.22

In this Review, the authors chart the history of growth hormone, from discovery to clinical development and therapeutic approval, and discuss the emerging pathophysiology and treatment of its related growth disorders, particularly in childhood. Finally, more recent developments and future strategies are highlighted.
Abstract | Full Text | PDF | Supplementary information

Global epidemiology of hyperthyroidism and hypothyroidism
Peter N. Taylor et al.

Published online: 23 March 2018
p301 | doi:10.1038/nrendo.2018.18

Iodine nutrition is a key determinant of thyroid disease risk, and continued vigilance against iodine deficiency remains essential. Here, Peter Taylor and colleagues review the global incidence and prevalence of thyroid disease, highlighting geographical differences and the effect of environmental factors, such as iodine supplementation, on these data.
Abstract | Full Text | PDF

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*Journal Citation Reports, Thomson, 2008. Nature Reviews Endocrinology was previously published as Nature Clinical Practice Endocrinology & Metabolism.

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