We bring you the latest news from the healthcare about the health care in the United Kingdom.

woensdag 14 maart 2018

Nature Reviews Cardiology - Table of Contents alert Volume 15 Issue 4

If you are unable to see the message below, click here to view.
Nature Reviews Cardiology  

Do you have a career question? 

The Naturejobs podcast features one-on-one Q&As, panel discussions and other exclusive content to help scientists with their careers. Hosted on the Naturejobs blog, the podcast is also available on iTunes and Soundcloud. 

Listen today!
April 2018 Volume 15 Number 4
Nature Reviews Cardiology cover
2016 2-year Impact Factor 14.299 Journal Metrics 2-year Median 10
In this issue
Research Highlights
News and Views
Also this month
 Featured article:
The NLRP3 inflammasome in acute myocardial infarction
Stefano Toldo & Antonio Abbate


Recommend to library
Nature Reviews Cardiology: Prevention of cardiovascular disease

This Series by Nature Reviews Cardiology features articles on the latest advances in the field of primary prevention of cardiovascular disease, from lifestyle modification strategies to clinical interventions targeting cardiovascular risk factors.

Read the Series
Comment: Air pollution and cardiovascular disease: a window of opportunity
Michael B. Hadley, Rajesh Vedanthan & Valentin Fuster

Published online: 03 January 2018
p193 | doi:10.1038/nrcardio.2017.207

The recent publication of The Lancet Commission on pollution and health is a watershed moment for one of the greatest challenges to cardiovascular health. In this Comment article, we discuss the global burden of air pollution on cardiovascular health.
Full Text | PDF


Atherosclerosis: A new role for lncRNAs in atherosclerosis
Published online: 01 March 2018
p195 | doi:10.1038/nrcardio.2018.18


Basic research: RNA deadenylation by CCR4-NOT controls heart function
Published online: 22 February 2018
p196 | doi:10.1038/nrcardio.2018.14


Heart failure: Macrophages promote cardiac fibrosis and diastolic dysfunction
Published online: 01 March 2018
p196 | doi:10.1038/nrcardio.2018.19


Basic research: Epigenetic map of heart development and disease
Published online: 15 February 2018
p197 | doi:10.1038/nrcardio.2018.12


Biomarkers: Extended predictive value of d-dimer
Published online: 15 February 2018
p198 | doi:10.1038/nrcardio.2018.13


Heart failure: Clonal haematopoiesis, IL-1β, and the NLRP3 inflammasome in HF
Published online: 13 March 2018
p198 | doi:10.1038/nrcardio.2018.22


Risk factors: Mental stress puts women's hearts at risk
Published online: 13 March 2018
p198 | doi:10.1038/nrcardio.2018.23




Hypertension: Lifestyle offsets genetic risk of hypertension | Heart failure: Histone deacetylases and diastolic dysfunction | Transplantation: Sirolimus after heart transplantation

Nature Reviews Cardiology
JOBS of the week
Senior Health Systems Scientist
NYU Winthrop Hospital
Postdoctoral Fellow / Pediatrics - 180000006J
The University of Tennessee Health Science Center (UTHSC)
Postdoctoral / Research Associate
University of Virginia
More Science jobs from
Nature Reviews Cardiology
Cardiac Rhythm Device Summit: Implantation, Management, and Follow Up
Dana Point, USA
More science events from
Arrhythmias: Atrial fibrillation in heart failure — time to revise the guidelines?
Luigi Di Biase & Mohammadali Habibi

Published online: 01 March 2018
p199 | doi:10.1038/nrcardio.2018.20

Catheter ablation for atrial fibrillation (AF) in patients with concomitant AF and heart failure (HF) is associated with significantly lower HF hospitalizations and all-cause mortality compared with medical therapy, according to the CASTLE-AF trial. This trial, along with previous trials such as AATAC, highlights the important role of AF ablation in the management of patients with HF and AF.
Full Text | PDF

Comorbidities: Cardiovascular disease and breast cancer
Melissa Moey & Javid Moslehi

Published online: 13 March 2018
p200 | doi:10.1038/nrcardio.2018.21

Advances in breast cancer therapy mean that more women are surviving cancer but are at increased risk of cardiovascular disease (CVD). In a statement released by the AHA, Mehta and colleagues summarize the intersection between breast cancer and CVD, and highlight the importance of vigilance in preventive measures.
Full Text | PDF

The NLRP3 inflammasome in acute myocardial infarction
Stefano Toldo & Antonio Abbate

Published online: 16 November 2017
p203 | doi:10.1038/nrcardio.2017.161

Ischaemic injury during an acute myocardial infarction (AMI) event is followed by an intense inflammatory response that occurs after reperfusion. The inflammasome is a protein complex involved in the regulation of this inflammatory response. In this Review, Toldo and Abbate summarize evidence supporting the therapeutic value of inflammasome-targeted strategies in the context of AMI.
Abstract | Full Text | PDF

Article series: Prevention of cardiovascular disease
Effects of stress on the development and progression of cardiovascular disease
Mika Kivimäki & Andrew Steptoe

Published online: 07 December 2017
p215 | doi:10.1038/nrcardio.2017.189

In this Review, Kivimäki and Steptoe assess the current evidence on the association between stress and cardiovascular disease, covering the multiple roles of stress in the development and triggering of disease and as a determinant of prognosis and outcome. In addition, they discuss the clinical and public health importance of major stressors and the implications for prevention and treatment of cardiovascular disease.
Abstract | Full Text | PDF

Epidemiology of cardiovascular disease in young individuals
Charlotte Andersson & Ramachandran S. Vasan

Published online: 12 October 2017
p230 | doi:10.1038/nrcardio.2017.154

In the past 2 decades, an increasing prevalence of risk factors for cardiovascular disease, such as obesity, physical inactivity, and diabetes mellitus, has been observed among young adults (aged 18-45 years) living in developed countries. In their Review, Andersson and Vasan discuss the evolving risk factor burden and available epidemiological data on cardiovascular disease in young adults.
Abstract | Full Text | PDF

Role of titin in cardiomyopathy: from DNA variants to patient stratification
James S. Ware & Stuart A. Cook

Published online: 14 December 2017
p241 | doi:10.1038/nrcardio.2017.190

The most common genetic predisposition to dilated cardiomyopathy (DCM) is truncating variation in the giant sarcomeric protein, titin. Ware and Cook review the molecular mechanisms of TTN gene variation in the pathogenesis of DCM, strategies for clinical interpretation of genetic variants for diagnosis, and the role of genetic stratification as a predictor of outcome and treatment response.
Abstract | Full Text | PDF | Supplementary information

Key Advances in Medicine eBook from Nature Reviews - FREE to download!
This essential resource summarizes the ground-breaking clinical and biomedical discoveries of 2017 and highlights the trends to watch out for in 2018, making it a must read eBook for anyone with an interest in medical science.

Download for free
nature events
Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here.

Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com
More Nature Events
Nature Reviews Cardiology was previously published as Nature Clinical Practice Cardiovascular Medicine.

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/myaccount
(You will need to log in to be recognised as a nature.com registrant).

For further technical assistance, please contact our registration department

For print subscription enquiries, please contact our subscription department

For other enquiries, please contact our feedback department

Springer Nature | One New York Plaza, Suite 4500 | New York | NY 10004-1562 | USA

Springer Nature's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne
San Diego - San Francisco - Washington - New York - Boston

Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at The Campus, 4 Crinan Street, London, N1 9XW.

© 2018 Macmillan Publishers Limited, part of Springer Nature. All Rights Reserved.

Springer Nature