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woensdag 7 maart 2018

Leukemia - Table of Contents alert Volume 32 Issue 3

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Volume 32, Issue 3 (March 2018)

In this issue
Original Articles
Letters to the Editor
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Original Articles

Acute myeloid leukemia

Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion

B Kumar, M Garcia, L Weng, X Jung, J L Murakami et al.

Leukemia 2017 32 :575 - 587; August 17, 2017; 10.1038/leu.2017.259


Abstract | Full Text

Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6-dependent manner

P Peña-Martínez, M Eriksson, R Ramakrishnan, M Chapellier, C Högberg et al.

Leukemia 2017 32 :588 - 596; August 18, 2017; 10.1038/leu.2017.261


Abstract | Full Text

RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia

M-A Hospital, A Jacquel, F Mazed, E Saland, C Larrue et al.

Leukemia 2017 32 :597 - 605; September 15, 2017; 10.1038/leu.2017.284


Abstract | Full Text

Acute lymphoblastic leukemia

Results of NOPHO ALL2008 treatment for patients aged 1–45 years with acute lymphoblastic leukemia

N Toft, H Birgens, J Abrahamsson, L Griškevicius, H Hallböök et al.

Leukemia 2017 32 :606 - 615; August 18, 2017; 10.1038/leu.2017.265


Abstract | Full Text

Targeting the vulnerability to NAD+ depletion in B-cell acute lymphoblastic leukemia

S Takao, W Chien, V Madan, D-C Lin, L-W Ding et al.

Leukemia 2017 32 :616 - 625; September 14, 2017; 10.1038/leu.2017.281


Abstract | Full Text

High-dose methotrexate therapy significantly improved survival of adult acute lymphoblastic leukemia: a phase III study by JALSG

T Sakura, F Hayakawa, I Sugiura, T Murayama, K Imai et al.

Leukemia 2017 32 :626 - 632; September 15, 2017; 10.1038/leu.2017.283


Abstract | Full Text

NG2 antigen is involved in leukemia invasiveness and central nervous system infiltration in MLL-rearranged infant B-ALL

C Prieto, B López-Millán, H Roca-Ho, R W Stam, D Romero-Moya et al.

Leukemia 2017 32 :633 - 644; September 25, 2017; 10.1038/leu.2017.294


Abstract | Full Text

Chronic lymphocytic leukemia

Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia

F Nadeu, G Clot, J Delgado, D Martín-García, T Baumann et al.

Leukemia 2017 32 :645 - 653; September 19, 2017; 10.1038/leu.2017.291


Abstract | Full Text

NOTCH1 mutations are associated with high CD49d expression in chronic lymphocytic leukemia: link between the NOTCH1 and the NF-?B pathways

D Benedetti, E Tissino, F Pozzo, T Bittolo, C Caldana et al.

Leukemia 2017 32 :654 - 662; September 22, 2017; 10.1038/leu.2017.296


Abstract | Full Text


Targeting nucleolin for better survival in diffuse large B-cell lymphoma

N Jain, H Zhu, T Khashab, Q Ye, B George et al.

Leukemia 2017 32 :663 - 674; July 10, 2017; 10.1038/leu.2017.215


Abstract | Full Text

Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets

K Karube, A Enjuanes, I Dlouhy, P Jares, D Martin-Garcia et al.

Leukemia 2017 32 :675 - 684; August 14, 2017; 10.1038/leu.2017.251


Abstract | Full Text

Differences between BCL2-break positive and negative follicular lymphoma unraveled by whole-exome sequencing

A Zamò, J Pischimarov, M Schlesner, P Rosenstiel, R Bomben et al.

Leukemia 2017 32 :685 - 693; August 21, 2017; 10.1038/leu.2017.270


Abstract | Full Text

Activation of RHOA–VAV1 signaling in angioimmunoblastic T-cell lymphoma

M Fujisawa, M Sakata-Yanagimoto, S Nishizawa, D Komori, P Gershon et al.

Leukemia 2017 32 :694 - 702; August 23, 2017; 10.1038/leu.2017.273


Abstract | Full Text

HDAC6 regulates microRNA-27b that suppresses proliferation, promotes apoptosis and target MET in diffuse large B-cell lymphoma

Y J Jia, Z B Liu, W G Wang, C B Sun, P Wei et al.

Leukemia 2017 32 :703 - 711; September 28, 2017; 10.1038/leu.2017.299


Abstract | Full Text

Multiple myeloma, gammopathies

Outcomes of maintenance therapy with lenalidomide or bortezomib in multiple myeloma in the setting of early autologous stem cell transplantation

R Chakraborty, E Muchtar, S K Kumar, F K Buadi, D Dingli et al.

Leukemia 2017 32 :712 - 718; August 14, 2017; 10.1038/leu.2017.256


Abstract | Full Text

Pomalidomide–dexamethasone in refractory multiple myeloma: long-term follow-up of a multi-cohort phase II clinical trial

S Ailawadhi, J R Mikhael, B R LaPlant, K M Laumann, S Kumar et al.

Leukemia 2017 32 :719 - 728; September 01, 2017; 10.1038/leu.2017.258


Abstract | Full Text

Clinical presentation and outcomes in light chain amyloidosis patients with non-evaluable serum free light chains

S Sidana, N Tandon, A Dispenzieri, M A Gertz, F K Buadi et al.

Leukemia 2017 32 :729 - 735; September 18, 2017; 10.1038/leu.2017.286


Abstract | Full Text

JAM-A as a prognostic factor and new therapeutic target in multiple myeloma

A G Solimando, A Brandl, K Mattenheimer, C Graf, M Ritz et al.

Leukemia 2017 32 :736 - 743; September 28, 2017; 10.1038/leu.2017.287


Abstract | Full Text

14-3-3ζ binds the proteasome, limits proteolytic function and enhances sensitivity to proteasome inhibitors

Y Gu, K Xu, C Torre, M Samur, B G Barwick et al.

Leukemia 2017 32 :744 - 751; September 19, 2017; 10.1038/leu.2017.288


Abstract | Full Text

Identification and characterization of HLA-A24-specific XBP1, CD138 (Syndecan-1) and CS1 (SLAMF7) peptides inducing antigens-specific memory cytotoxic T lymphocytes targeting multiple myeloma

J Bae, T Hideshima, G L Zhang, J Zhou, D B Keskin et al.

Leukemia 2017 32 :752 - 764; November 01, 2017; 10.1038/leu.2017.316


Abstract | Full Text

Stem cell transplantation

Extracellular vesicles as potential biomarkers of acute graft-vs-host disease

G Lia, L Brunello, S Bruno, A Carpanetto, P Omedè et al.

Leukemia 2017 32 :765 - 773; August 30, 2017; 10.1038/leu.2017.277


Abstract | Full Text

Molecular targets for therapy

Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling

E I Andersson, S Pützer, B Yadav, O Dufva, S Khan et al.

Leukemia 2017 32 :774 - 787; August 14, 2017; 10.1038/leu.2017.252


Abstract | Full Text

Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia

S Degryse, C E de Bock, S Demeyer, I Govaerts, S Bornschein et al.

Leukemia 2017 32 :788 - 800; August 30, 2017; 10.1038/leu.2017.276


Abstract | Full Text


Toll-like receptor 2 costimulation potentiates the antitumor efficacy of CAR T Cells

Y Lai, J Weng, X Wei, L Qin, P Lai et al.

Leukemia 2017 32 :801 - 808; August 03, 2017; 10.1038/leu.2017.249


Abstract | Full Text

Transcriptional control and signal transduction, cell cycle

The T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling

T Girardi, S Vereecke, S O Sulima, Y Khan, L Fancello et al.

Leukemia 2017 32 :809 - 819; July 24, 2017; 10.1038/leu.2017.225


Abstract | Full Text

Phosphorylation of SOS1 on tyrosine 1196 promotes its RAC GEF activity and contributes to BCR-ABL leukemogenesis

S Gerboth, E Frittoli, A Palamidessi, F C Baltanas, M Salek et al.

Leukemia 2017 32 :820 - 827; August 18, 2017; 10.1038/leu.2017.267


Abstract | Full Text

C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation

A E Marneth, K H M Prange, A S A Al Hinai, S M Bergevoet, N Tesi et al.

Leukemia 2017 32 :828 - 836; September 05, 2017; 10.1038/leu.2017.280


Abstract | Full Text

Letters to the Editor

Prognostic significance of ASXL1 mutation types and allele burden in myelofibrosis

A Tefferi, T L Lasho, C Finke, N Gangat, C A Hanson et al.

Leukemia 2017 32 :837 - 839; November 01, 2017; 10.1038/leu.2017.318


Abstract | Full Text

A novel genetic and morphologic phenotype of ARID2-mediated myelodysplasia

H Sakai, N Hosono, H Nakazawa, B Przychodzen, C Polprasert et al.

Leukemia 2017 32 :839 - 843; November 03, 2017; 10.1038/leu.2017.319


Abstract | Full Text

Combination of a novel HDAC6 inhibitor ACY-241 and anti-PD-L1 antibody enhances anti-tumor immunity and cytotoxicity in multiple myeloma

A Ray, D S Das, Y Song, T Hideshima, Y-T Tai et al.

Leukemia 2017 32 :843 - 846; November 06, 2017; 10.1038/leu.2017.322


Abstract | Full Text

Bruton's tyrosine kinase and RAC1 promote cell survival in MLL-rearranged acute myeloid leukemia

S C Nimmagadda, S Frey, B Edelmann, C Hellmich, L Zaitseva et al.

Leukemia 2017 32 :846 - 849; November 07, 2017; 10.1038/leu.2017.324


Abstract | Full Text

Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53

S Chen, R Gao, C Yao, M Kobayashi, S Z Liu et al.

Leukemia 2017 32 :850 - 854; November 16, 2017; 10.1038/leu.2017.325


Abstract | Full Text

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