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Cell Death and Disease - Table of Contents alert Volume 9, February 2018

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Cell Death & Disease

Volume 9 (February 2018)

In this issue
Review Article
Meeting Report



AGO1 may influence the prognosis of hepatocellular carcinoma through TGF-ß pathway

Miao Wang, Lyu Zhang, Zeyang Liu, Jiamin Zhou, Qi Pan et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0338-y

Abstract | Full Text

Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors

Raeeka Khamari, Anne Trinh, Pierre Elliott Gabert, Paola Corazao-Rozas, Samuel Riveros-Cruz et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0340-4

Abstract | Full Text

Lysine methyltransferase SMYD2 promotes triple negative breast cancer progression

Linda Xiaoyan Li, Julie Xia Zhou, James P. Calvet, Andrew K. Godwin, Roy A. Jensen et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0347-x

Abstract | Full Text

Histone deacetylase inhibitors protect against cisplatin-induced acute kidney injury by activating autophagy in proximal tubular cells

Jing Liu, Man J. Livingston, Guie Dong, Chengyuan Tang, Yunchao Su et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0374-7

Abstract | Full Text

Plasma exosomes induced by remote ischaemic preconditioning attenuate myocardial ischaemia/reperfusion injury by transferring miR-24

Wen Minghua, Gong Zhijian, Huang Chahua, Liang Qiang, Xu Minxuan et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0274-x

Abstract | Full Text

Kupffer cell-derived TNF-a promotes hepatocytes to produce CXCL1 and mobilize neutrophils in response to necrotic cells

Li Su, Na Li, Hua Tang, Ziyang Lou, Xiaodan Chong et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0377-4

Abstract | Full Text

CASC2/miR-24/miR-221 modulates the TRAIL resistance of hepatocellular carcinoma cell through caspase-8/caspase-3

Xiaoxin Jin, Lifeng Cai, Changfa Wang, Xiaofeng Deng, Shengen Yi et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0350-2

Abstract | Full Text

TCF7L2 positively regulates aerobic glycolysis via the EGLN2/HIF-1a axis and indicates prognosis in pancreatic cancer

Jinfeng Xiang, Qiangsheng Hu, Yi Qin, Shunrong Ji, Wenyan Xu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0367-6

Abstract | Full Text

Circular RNA GRB10 as a competitive endogenous RNA regulating nucleus pulposus cells death in degenerative intervertebral disk

Wei Guo, Bin Zhang, Kun Mu, Shi-Qing Feng, Zhan-Yin Dong et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0232-z

Abstract | Full Text

Estradiol signaling mediates gender difference in visceral adiposity via autophagy

Zhipeng Tao, Louise D. Zheng, Cayleen Smith, Jing Luo, Alex Robinson et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0372-9

Abstract | Full Text

DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice

Shijie Zheng, Lirong Xiao, Yu Liu, Yujiao Wang, Lin Cheng et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0349-8

Abstract | Full Text

Role of autophagy in modulating post-maturation aging of mouse oocytes

Fei-Hu Lin, Wei-Ling Zhang, Hong Li, Xiao-Dan Tian, Jie Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0368-5

Abstract | Full Text

Arginase-II activates mTORC1 through myosin-1b in vascular cell senescence and apoptosis


Cell Death & Disease 2018 9: 10.1038/s41419-018-0356-9

Abstract | Full Text

Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms

João Agostinho Machado-Neto, Bruna Alves Fenerich, Renata Scopim-Ribeiro, Christopher A. Eide, Juan Luiz Coelho-Silva et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0256-4

Abstract | Full Text

PU.1/microRNA-142-3p targets ATG5/ATG16L1 to inactivate autophagy and sensitize hepatocellular carcinoma cells to sorafenib

Kai Zhang, Jing Chen, Hao Zhou, Ying Chen, Yingru Zhi et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0344-0

Abstract | Full Text

Atm reactivation reverses ataxia telangiectasia phenotypes in vivo

Sara Di Siena, Federica Campolo, Roberto Gimmelli, Chiara Di Pietro, Daniela Marazziti et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0357-8

Abstract | Full Text

PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis

Bin Zhao, Lei Liu, Jun Mao, Zhiwei Zhang, Qifei Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0348-9

Abstract | Full Text

Co-inhibition of BET proteins and NF-?B as a potential therapy for colorectal cancer through synergistic inhibiting MYC and FOXM1 expressions

Tingyu Wu, Guanghui Wang, Wei Chen, Zhehui Zhu, Yun Liu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0354-y

Abstract | Full Text

Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration

Gautam Pareek, Ruth E. Thomas & Leo J. Pallanck

Cell Death & Disease 2018 9: 10.1038/s41419-018-0365-8

Abstract | Full Text

IL-32 gamma reduces lung tumor development through upregulation of TIMP-3 overexpression and hypomethylation

Jaesuk Yun, Mi Hee Park, Dong Ju Son, Kyung Tak Nam, Dae Bong Moon et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0375-6

Abstract | Full Text

Long glucocorticoid-induced leucine zipper regulates human thyroid cancer cell proliferation

Emira Ayroldi, Maria Grazia Petrillo, Maria Cristina Marchetti, Lorenza Cannarile, Simona Ronchetti et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0346-y

Abstract | Full Text

Identification of a novel microRNA-mRNA regulatory biomodule in human prostate cancer

Yanqiong Zhang, Funeng Jiang, Huichan He, Jianheng Ye, Xia Mao et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0293-7

Abstract | Full Text

Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development

Xiaomin Su, Chenglei Wu, Xiaoying Ye, Ming Zeng, Zhujun Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0370-y

Abstract | Full Text

LINC01016 promotes the malignant phenotype of endometrial cancer cells by regulating the miR-302a-3p/miR-3130-3p/NFYA/SATB1 axis

Xin Pan, Da Li, Jianing Huo, Fanfei Kong, Hui Yang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0291-9

Abstract | Full Text

ALCAM+ stromal cells: role in giant cell tumor of bone progression

Zhenhua Zhou, Yan Li, Xudong Wang, Jingjing Hu, Muyu Kuang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0361-z

Abstract | Full Text

The interactome and spatial redistribution feature of Ca2+ receptor protein calmodulin reveals a novel role in invadopodia-mediated invasion

Tao Li, Li Yi, Long Hai, Haiwen Ma, Zhennan Tao et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0253-7

Abstract | Full Text

Ceramide-induced BOK promotes mitochondrial fission in preeclampsia

Jonathan Ausman, Joelcio Abbade, Leonardo Ermini, Abby Farrell, Andrea Tagliaferro et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0360-0

Abstract | Full Text

Contribution of TMEM16F to pyroptotic cell death

Jiraporn Ousingsawat, Podchanart Wanitchakool, Rainer Schreiber & Karl Kunzelmann

Cell Death & Disease 2018 9: 10.1038/s41419-018-0373-8

Abstract | Full Text

Glutamate-induced and NMDA receptor-mediated neurodegeneration entails P2Y1 receptor activation

Ana P. Simões, Carla G. Silva, Joana M. Marques, Daniela Pochmann, Lisiane O. Porciúncula et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0351-1

Abstract | Full Text

Dysfunctional immunoregulation in human liver allograft rejection associated with compromised galectin-1/CD7 pathway function

Sidong Wei, Ding Cao, Zuojin Liu, Jinheng Li, Hao Wu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0220-3

Abstract | Full Text

Induction of ER and mitochondrial stress by the alkylphosphocholine erufosine in oral squamous cell carcinoma cells

Shariq S. Ansari, Ashwini K. Sharma, Himanshu Soni, Doaa M. Ali, Björn Tews et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0342-2

Abstract | Full Text

GRK5 functions as an oncogenic factor in non-small-cell lung cancer

Li-Ping Jiang, Song-Qing Fan, Qiu-Xia Xiong, Yong-Chun Zhou, Zuo-Zhang Yang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0299-1

Abstract | Full Text

Long noncoding RNA Gomafu upregulates Foxo1 expression to promote hepatic insulin resistance by sponging miR-139-5p


Cell Death & Disease 2018 9: 10.1038/s41419-018-0321-7

Abstract | Full Text

Calpain7 impairs embryo implantation by downregulating ß3-integrin expression via degradation of HOXA10

Qiang Yan, Chenyang Huang, Yue Jiang, Huizhi Shan, Ruiwei Jiang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0317-3

Abstract | Full Text

The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane

Philip Böhler, Fabian Stuhldreier, Ruchika Anand, Arun Kumar Kondadi, David Schlütermann et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0312-8

Abstract | Full Text

Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells

Mélanie Marie, Karine Bigot, Claire Angebault, Coralie Barrau, Pauline Gondouin et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0331-5

Abstract | Full Text

miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg)

Chuanyong Zhang, Hongbing shen, Yunjie Lu, Ji Gao, Shaopeng Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0298-2

Abstract | Full Text

Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes

Myoung Sup Shim, Keun-Young Kim, Jung Hyun Bu, Hye Seung Nam, Seung Won Jeong et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0171-8

Abstract | Full Text

Erythrocyte glutathione transferase in kidney transplantation: a probe for kidney detoxification efficiency

Alessio Bocedi, Annalisa Noce, Valentina Rovella, Giulia Marrone, Giada Cattani et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0289-3

Abstract | Full Text

ALS-related human cortical and motor neurons survival is differentially affected by Sema3A


Cell Death & Disease 2018 9: 10.1038/s41419-018-0294-6

Abstract | Full Text

Gambogenic acid inhibits fibroblast growth factor receptor signaling pathway in erlotinib-resistant non-small-cell lung cancer and suppresses patient-derived xenograft growth

Linfeng Xu, Xiaoxiao Meng, Naihan Xu, Wenwei Fu, Hongsheng Tan et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0314-6

Abstract | Full Text

NIT1 suppresses tumour proliferation by activating the TGFß1–Smad2/3 signalling pathway in colorectal cancer

Chun Lin, Jianming Zhang, Yanxia Lu, Xiaomin Li, Wenjuan Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0333-3

Abstract | Full Text

CRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing

Marinella G. Callow, Colin Watanabe, Katherine E. Wickliffe, Russell Bainer, Sarah Kummerfield et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0301-y

Abstract | Full Text

Norisoboldine, a natural AhR agonist, promotes Treg differentiation and attenuates colitis via targeting glycolysis and subsequent NAD+/SIRT1/SUV39H1/H3K9me3 signaling pathway

Qi Lv, Kai Wang, Simiao Qiao, Ling Yang, Yirong Xin et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0297-3

Abstract | Full Text

Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting ß-catenin by activating PKM2 and inactivating PTEN

Qidi Zheng, Zhuojia Lin, Jie Xu, Yanan Lu, Qiuyu Meng et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0305-7

Abstract | Full Text

Cinacalcet-mediated activation of the CaMKKß-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy

Ji Hee Lim, Hyung Wook Kim, Min Young Kim, Tae Woo Kim, Eun Nim Kim et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0324-4

Abstract | Full Text

The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity

Jose M. Mellado-Gil, Esther Fuente-Martín, Petra I. Lorenzo, Nadia Cobo-Vuilleumier, Livia López-Noriega et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0272-z

Abstract | Full Text

Non-alcoholic fatty liver disease severity is modulated by transglutaminase type 2

Mauro Piacentini, Andrea Baiocchini, Franca Del Nonno, Gerry Melino, Nickolai A. Barlev et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0292-8

Abstract | Full Text

Predictive and preventive significance of AMPK activation on hepatocarcinogenesis in patients with liver cirrhosis

Xiaoli Yang, Yan Liu, Menghui Li, Hao Wu, Yunbing Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0308-4

Abstract | Full Text

The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence

Siew-Min Ong, Eva Hadadi, Truong-Minh Dang, Wei-Hseun Yeap, Crystal Tze-Ying Tan et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0327-1

Abstract | Full Text

Nuclear factor 90 promotes angiogenesis by regulating HIF-1a/VEGF-A expression through the PI3K/Akt signaling pathway in human cervical cancer

Wenqian Zhang, Zhengai Xiong, Tianqin Wei, Qiumeng Li, Ying Tan et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0334-2

Abstract | Full Text

Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway

Xuerong Sun, Benyan Shi, Huiling Zheng, Ling Min, Jie Yang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0303-9

Abstract | Full Text

EGFR-PI3K-PDK1 pathway regulates YAP signaling in hepatocellular carcinoma: the mechanism and its implications in targeted therapy

Hongwei Xia, Xinyu Dai, Huangfei Yu, Sheng Zhou, Zhenghai Fan et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0302-x

Abstract | Full Text

G9A promotes gastric cancer metastasis by upregulating ITGB3 in a SET domain-independent manner

Lei Hu, Ming-de Zang, He-xiao Wang, Bao-gui Zhang, Zhen-qiang Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0322-6

Abstract | Full Text

Rhinovirus 3C protease suppresses apoptosis and triggers caspase-independent cell death

Mark Lötzerich, Pascal S. Roulin, Karin Boucke, Robert Witte, Oleg Georgiev et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0306-6

Abstract | Full Text

Intravenous injections of the oncolytic virus M1 as a novel therapy for muscle-invasive bladder cancer

Cheng Hu, Ying Liu, Yuan Lin, Jian-Kai Liang, Wen-Wen Zhong et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0325-3

Abstract | Full Text

Glucocorticoids promote apoptosis of proinflammatory monocytes by inhibiting ERK activity

Adrian Achuthan, Ahmad S. M. Aslam, Quyen Nguyen, Pui-Yeng Lam, Andrew J. Fleetwood et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0332-4

Abstract | Full Text

Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence


Cell Death & Disease 2018 9: 10.1038/s41419-018-0300-z

Abstract | Full Text

Knockout of zebrafish interleukin 7 receptor (IL7R) by the CRISPR/Cas9 system delays retinal neurodevelopment

Shijiao Cai, Yang Chen, Yue Shang, Jianlin Cui, Zongjin Li et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0337-z

Abstract | Full Text

PEAK1, acting as a tumor promoter in colorectal cancer, is regulated by the EGFR/KRas signaling axis and miR-181d

Lanlan Huang, Chuangyu Wen, Xiangling Yang, Qiong Lou, Xiaoyan Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0320-8

Abstract | Full Text

Hemopexin is required for adult neurogenesis in the subventricular zone/olfactory bulb pathway

Yanling Zhu, Yang Qiu, Mengjia Chen, Yi Zhang, Li Cao et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0328-0

Abstract | Full Text

Chir99021 and Valproic acid reduce the proliferative advantage of Apc mutant cells

Alistair J. Langlands, Thomas D. Carroll, Yu Chen & Inke Näthke

Cell Death & Disease 2018 9: 10.1038/s41419-017-0199-9

Abstract | Full Text

Toll-like receptor 4 modulation influences human neural stem cell proliferation and differentiation

Chiara Grasselli, Daniela Ferrari, Cristina Zalfa, Matias Soncini, Gianluigi Mazzoccoli et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0139-8

Abstract | Full Text

CFTR mutation enhances Dishevelled degradation and results in impairment of Wnt-dependent hematopoiesis

Huaqin Sun, Yan Wang, Jieting Zhang, Yan Chen, Yanyan Liu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0311-9

Abstract | Full Text

S100A4 promotes lung tumor development through ß-catenin pathway-mediated autophagy inhibition

Shasha Hou, Tian Tian, Dianwen Qi, Kaiji Sun, Qi Yuan et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0319-1

Abstract | Full Text

Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer

Yang-An Wen, Xiaopeng Xiong, Yekaterina Y. Zaytseva, Dana L. Napier, Emma Vallee et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0330-6

Abstract | Full Text

TR4 nuclear receptor suppresses HCC cell invasion via downregulating the EphA2 expression

Ren'an Jin, Hui Lin, Gonghui Li, Junjie Xu, Liang Shi et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0287-5

Abstract | Full Text

Downregulation of PERK activity and eIF2a serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells

Jothilatha Krishnamoorthy, Clara Tenkerian, Jyotsana Gupta, Nour Ghaddar, Shuo Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0326-2

Abstract | Full Text

The long non-coding RNA FOXD2-AS1 promotes bladder cancer progression and recurrence through a positive feedback loop with Akt and E2F1

Feng Su, Wang He, Changhao Chen, Mo Liu, Hongwei Liu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0275-9

Abstract | Full Text

Dural effects of oxidative stress on cardiomyogenesis via Gata4 transcription and protein ubiquitination


Cell Death & Disease 2018 9: 10.1038/s41419-018-0281-y

Abstract | Full Text

Lup-20(29)-en-3ß,28-di-yl-nitrooxy acetate affects MCF-7 proliferation through the crosstalk between apoptosis and autophagy in mitochondria

Xiaoning Yan, Lei Yang, Gaili Feng, Zhuli Yu, Minjie Xiao et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0255-5

Abstract | Full Text

Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy

Valentina Celestini, Tugsan Tezil, Luciana Russo, Candida Fasano, Paola Sanese et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0336-0

Abstract | Full Text

Long non-coding RNA PVT1 predicts poor prognosis and induces radioresistance by regulating DNA repair and cell apoptosis in nasopharyngeal carcinoma

Yi He, Yizhou Jing, Fang Wei, Yanyan Tang, Liting Yang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0265-y

Abstract | Full Text

Rage induces hepatocellular carcinoma proliferation and sorafenib resistance by modulating autophagy

Jun Li, Peng-Wen Wu, Yuan Zhou, Bo Dai, Peng-Fei Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0329-z

Abstract | Full Text

Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis

Chiara Rossi, Melania Cusimano, Martina Zambito, Annamaria Finardi, Alessia Capotondo et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0288-4

Abstract | Full Text

A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3

Ruoqiu Fu, Qin Deng, Hongwei Zhang, Xiaoye Hu, Yunong Li et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0276-8

Abstract | Full Text

MYCN drives glutaminolysis in neuroblastoma and confers sensitivity to an ROS augmenting agent

Tingting Wang, Lingling Liu, Xuyong Chen, Yuqing Shen, Gaojian Lian et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0295-5

Abstract | Full Text

Granzyme B deficiency promotes osteoblastic differentiation and calcification of vascular smooth muscle cells in hypoxic pulmonary hypertension

Min Mao, Min Zhang, Anqi Ge, Xin Ge, Rui Gu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0315-5

Abstract | Full Text

Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification

Qingquan Zhang, Ru Huang, Youqiong Ye, Xiaoxia Guo, Jun Lu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0283-9

Abstract | Full Text

SPRY2 is a novel MET interactor that regulates metastatic potential and differentiation in rhabdomyosarcoma

Masum Saini, Aakanksha Verma & Sam J. Mathew

Cell Death & Disease 2018 9: 10.1038/s41419-018-0261-2

Abstract | Full Text

Baicalin administration attenuates hyperglycemia-induced malformation of cardiovascular system

Guang Wang, Jianxin Liang, Lin-rui Gao, Zhen-peng Si, Xiao-tan Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0318-2

Abstract | Full Text

The chemokine receptor CCR10 promotes inflammation-driven hepatocarcinogenesis via PI3K/Akt pathway activation

Qiong Wu, Jin-xian Chen, Yu Chen, Li-li Cai, Xiao-zhong Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0267-9

Abstract | Full Text

Microfluidic cell sorting by stiffness to examine heterogenic responses of cancer cells to chemotherapy

Muhymin Islam, Roman Mezencev, Brynn McFarland, Hannah Brink, Betsy Campbell et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0266-x

Abstract | Full Text

Let-7c inhibits cholangiocarcinoma growth but promotes tumor cell invasion and growth at extrahepatic sites

Yu Xie, Hang Zhang, Xing-Jun Guo, Ye-Chen Feng, Rui-Zhi He et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0286-6

Abstract | Full Text

Canagliflozin mediated dual inhibition of mitochondrial glutamate dehydrogenase and complex I: an off-target adverse effect

Philipp F. Secker, Sascha Beneke, Nadja Schlichenmaier, Johannes Delp, Simon Gutbier et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0273-y

Abstract | Full Text

Non-toxic engineered carbon nanodiamond concentrations induce oxidative/nitrosative stress, imbalance of energy metabolism, and mitochondrial dysfunction in microglial and alveolar basal epithelial cells

Claudia G. Fresta, Aishik Chakraborty, Manjula B. Wijesinghe, Angela M. Amorini, Giacomo Lazzarino et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0280-z

Abstract | Full Text

The cytotoxicity of coxsackievirus B3 is associated with a blockage of autophagic flux mediated by reduced syntaxin 17 expression

Lang Tian, Yeyi Yang, Chunyun Li, Jia Chen, Zhuoying Li et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0271-0

Abstract | Full Text

Glycogen synthase kinase-3ß inhibition promotes lysosome-dependent degradation of c-FLIPL in hepatocellular carcinoma

Na Zhang, Xiaojia Liu, Lu Liu, Zhesong Deng, Qingxuan Zeng et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0309-3

Abstract | Full Text

BRM270 inhibits cancer stem cell maintenance via microRNA regulation in chemoresistant A549 lung adenocarcinoma cells

Taeho Kwon, Nisansala Chandimali, Do Luong Huynh, Jiao Jiao Zhang, Nameun Kim et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0277-7

Abstract | Full Text

Pyruvate kinase M2 regulates photoreceptor structure, function, and viability

Ammaji Rajala, Yuhong Wang, Richard S. Brush, Kristine Tsantilas, Connor S. R. Jankowski et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0296-4

Abstract | Full Text

Impaired autophagic flux is associated with the severity of trauma and the role of A2AR in brain cells after traumatic brain injury

Xu-Jia Zeng, Ping Li, Ya-Lei Ning, Yan Zhao, Yan Peng et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0316-4

Abstract | Full Text

The oncogene Etv5 promotes MET in somatic reprogramming and orchestrates epiblast/primitive endoderm specification during mESCs differentiation

Jinglong Zhang, Hongxia Cao, Jing Xie, Chen Fan, Youlong Xie et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0335-1

Abstract | Full Text

Long noncoding RNA GAS5 promotes bladder cancer cells apoptosis through inhibiting EZH2 transcription

Miao Wang, Chen Guo, Liang Wang, Gang Luo, Chao Huang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0264-z

Abstract | Full Text

Loss of NDRG2 in liver microenvironment inhibits cancer liver metastasis by regulating tumor associate macrophages polarization

Mengyang Li, Xiaofeng Lai, Ying Zhao, Yuan Zhang, Minghui Li et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0284-8

Abstract | Full Text

Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip

Sasan Jalili-Firoozinezhad, Rachelle Prantil-Baun, Amanda Jiang, Ratnakar Potla, Tadanori Mammoto et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0304-8

Abstract | Full Text

STK17B promotes carcinogenesis and metastasis via AKT/GSK-3ß/Snail signaling in hepatocellular carcinoma

Yaliang Lan, Jihua Han, Yan Wang, Jiabei Wang, Guangchao Yang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0262-1

Abstract | Full Text

Lenalidomide regulates CNS autoimmunity by promoting M2 macrophages polarization

Qinjie Weng, Jiaying Wang, Jiajia Wang, Jing Wang, Fahmida Sattar et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0290-x

Abstract | Full Text

Genetic modification to induce CXCR2 overexpression in mesenchymal stem cells enhances treatment benefits in radiation-induced oral mucositis

Zongshan Shen, Jiancheng Wang, Qiting Huang, Yue Shi, Zhewei Wei et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0310-x

Abstract | Full Text

Fibroblast growth factor-21 prevents diabetic cardiomyopathy via AMPK-mediated antioxidation and lipid-lowering effects in the heart

Hong Yang, Anyun Feng, Sundong Lin, Lechu Yu, Xiufei Lin et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0307-5

Abstract | Full Text

Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling

Zhou Wang, Lingman Ma, Mengqi Su, Yiran Zhou, Ke Mao et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0223-0

Abstract | Full Text

Effect of mitochondrial uncouplers niclosamide ethanolamine (NEN) and oxyclozanide on hepatic metastasis of colon cancer

Amer Alasadi, Michael Chen, G. V. T. Swapna, Hanlin Tao, Jingjing Guo et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0092-6

Abstract | Full Text

KRAS induces lung tumorigenesis through microRNAs modulation

Lei Shi, Justin Middleton, Young-Jun Jeon, Peter Magee, Dario Veneziano et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0243-9

Abstract | Full Text

Inhibition of KRAS-dependent lung cancer cell growth by deltarasin: blockage of autophagy increases its cytotoxicity

Elaine Lai Han Leung, Lian Xiang Luo, Zhong Qiu Liu, Vincent Kam Wai Wong, Lin Lin Lu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0065-9

Abstract | Full Text

Human umbilical cord mesenchymal stem cell-derived extracellular vesicles promote lung adenocarcinoma growth by transferring miR-410

Liyang Dong, Yanan Pu, Lina Zhang, Qianqian Qi, Lei Xu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0323-5

Abstract | Full Text

Association of cytosolic sialidase Neu2 with plasma membrane enhances Fas-mediated apoptosis by impairing PI3K-Akt/mTOR-mediated pathway in pancreatic cancer cells

Shalini Nath, Chhabinath Mandal, Uttara Chatterjee & Chitra Mandal

Cell Death & Disease 2018 9: 10.1038/s41419-017-0191-4

Abstract | Full Text

Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival

Lian Wang, Zhouchun Shang, Yang Zhou, Xinyu Hu, Yihong Chen et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0242-x

Abstract | Full Text

Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson's disease

Alessandro Tozzi, Michela Tantucci, Saverio Marchi, Petra Mazzocchetti, Michele Morari et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0221-2

Abstract | Full Text

Glutamine metabolism regulates FLIP expression and sensitivity to TRAIL in triple-negative breast cancer cells

Marta Mauro-Lizcano & Abelardo López-Rivas

Cell Death & Disease 2018 9: 10.1038/s41419-018-0263-0

Abstract | Full Text

Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+ exchanger 3 downregulation

Serenella Anzilotti, Paola Brancaccio, Giuseppe Simeone, Valeria Valsecchi, Antonio Vinciguerra et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0227-9

Abstract | Full Text

Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat

Jian Chen, Jun-Jun Xie, Ke-Si Shi, Yun-Tao Gu, Cong-Cong Wu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0217-y

Abstract | Full Text

Mechanical stretch-induced osteogenic differentiation of human jaw bone marrow mesenchymal stem cells (hJBMMSCs) via inhibition of the NF-?B pathway

Xiaoyan Chen, Yuan Liu, Wanghui Ding, Jiejun Shi, Shenglai Li et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0279-5

Abstract | Full Text

MiR-22 suppresses epithelial–mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loop

Mingjie Xu, Jiangfeng Li, Xiao Wang, Shuai Meng, Jiaying Shen et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0206-1

Abstract | Full Text

Ablation of protein phosphatase 5 (PP5) leads to enhanced both bone and cartilage development in mice

Jun Wang, Yong Cao, Bin Qiu, Jianyong Du, Tingting Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0254-6

Abstract | Full Text

BRD4 regulates cellular senescence in gastric cancer cells via E2F/miR-106b/p21 axis


Cell Death & Disease 2018 9: 10.1038/s41419-017-0181-6

Abstract | Full Text

Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testis

Qing Wen, Nan Li, Xiang Xiao, Wing-yee Lui, Darren S. Chu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0201-6

Abstract | Full Text

RIPK1-dependent cell death: a novel target of the Aurora kinase inhibitor Tozasertib (VX-680)

Sofie Martens, Vera Goossens, Lars Devisscher, Sam Hofmans, Polien Claeys et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0245-7

Abstract | Full Text

Temozolomide–perillyl alcohol conjugate downregulates O6-methylguanin DNA methltransferase via inducing ubiquitination-dependent proteolysis in non-small cell lung cancer

Xingguo Song, Li Xie, Minghui Chang, Xinran Geng, Xingwu Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0193-2

Abstract | Full Text

Alterations of specific chromatin conformation affect ATRA-induced leukemia cell differentiation

Yanjian Li, Yi He, Zhengyu Liang, Yang Wang, Fengling Chen et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0173-6

Abstract | Full Text

Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux

Anupama Rai, Pankaj Kumar Singh, Virender Singh, Vipendra Kumar, Rohit Mishra et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0190-5

Abstract | Full Text

Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death

Stefano Thellung, Beatrice Scoti, Alessandro Corsaro, Valentina Villa, Mario Nizzari et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0252-8

Abstract | Full Text

Regulation of senescence escape by the cdk4–EZH2–AP2M1 pathway in response to chemotherapy

Mélanie Le Duff, Julien Gouju, Barbara Jonchère, Jordan Guillon, Bertrand Toutain et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0209-y

Abstract | Full Text

bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats

Dawei Sun, Wenying Wang, Xintao Wang, Yan Wang, Xiaotao Xu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0229-7

Abstract | Full Text

miR-27b-3p inhibits proliferation and potentially reverses multi-chemoresistance by targeting CBLB/GRB2 in breast cancer cells

Danni Chen, Wengong Si, Jiaying Shen, Chengyong Du, Weiyang Lou et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0211-4

Abstract | Full Text

Regenerative potential of tonsil mesenchymal stem cells on surgical cutaneous defect

Sung-Chan Shin, Yoojin Seo, Hee Young Park, Da-Woon Jung, Tae-Hoon Shin et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0248-4

Abstract | Full Text

Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling

Hong-Jin Zhao, Christian Klausen, Yan Li, Hua Zhu, Yan-Ling Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0230-1

Abstract | Full Text

Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth

Chao Zhou, Hongwei Sun, Chen Zheng, Jing Gao, Qingzi Fu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0196-z

Abstract | Full Text

Homocysteine activates autophagy by inhibition of CFTR expression via interaction between DNA methylation and H3K27me3 in mouse liver

Anning Yang, Yun Jiao, Songhao Yang, Mei Deng, Xiaoling Yang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0216-z

Abstract | Full Text

Plasma Hemopexin ameliorates murine spinal cord injury by switching microglia from the M1 state to the M2 state

Dunxin Han, Zhongwang Yu, Weili Liu, Dou Yin, Yingyan Pu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0236-8

Abstract | Full Text

LanCL1 protects prostate cancer cells from oxidative stress via suppression of JNK pathway

Jianqing Wang, Qianyi Xiao, Xu Chen, Shijun Tong, Jianliang Sun et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0207-0

Abstract | Full Text

Combination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1ß production

Anthony C Tang, Seyed M Rahavi, Shan-Yu Fung, Henry Y Lu, Hong Yang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0194-1

Abstract | Full Text

Sphingolipid de novo biosynthesis is essential for intestine cell survival and barrier function

Zhiqiang Li, Inamul Kabir, Gladys Tietelman, Chongmin Huan, Jianglin Fan et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0214-1

Abstract | Full Text

PDE5 inhibition eliminates cancer stem cells via induction of PKA signaling

Saskia Klutzny, Anna Anurin, Barbara Nicke, Joseph L. Regan, Martin Lange et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0202-5

Abstract | Full Text

Downregulation of ß1,4-galactosyltransferase 5 improves insulin resistance by promoting adipocyte commitment and reducing inflammation

Shu-Fen Li, Cui-Song Zhu, Yu-Meng Wang, Xin-Xin Xie, Liu-Ling Xiao et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0239-5

Abstract | Full Text

miR-143-3p targeting of ITGA6 suppresses tumour growth and angiogenesis by downregulating PLGF expression via the PI3K/AKT pathway in gallbladder carcinoma

Yun-Peng Jin, Yun-Ping Hu, Xiang-Song Wu, Yao-Shi Wu, Yuan-Yuan Ye et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0258-2

Abstract | Full Text

Osteopontin promotes metastasis of intrahepatic cholangiocarcinoma through recruiting MAPK1 and mediating Ser675 phosphorylation of ß-Catenin

Yan Zheng, Chuang Zhou, Xin-Xin Yu, Chao Wu, Hu-Liang Jia et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0226-x

Abstract | Full Text

Long noncoding RNA PANDAR blocks CDKN1A gene transcription by competitive interaction with p53 protein in gastric cancer

Jun Liu, Qiwen Ben, Eryi Lu, Xiangyi He, Xiaoqun Yang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0246-6

Abstract | Full Text

Multiple molecular mechanisms form a positive feedback loop driving amyloid ß42 peptide-induced neurotoxicity via activation of the TRPM2 channel in hippocampal neurons

Xin Li & Lin-Hua Jiang

Cell Death & Disease 2018 9: 10.1038/s41419-018-0270-1

Abstract | Full Text

LncRNA NCK1-AS1 promotes proliferation and induces cell cycle progression by crosstalk NCK1-AS1/miR-6857/CDK1 pathway


Cell Death & Disease 2018 9: 10.1038/s41419-017-0249-3

Abstract | Full Text

Neuroglobin boosts axon regeneration during ischemic reperfusion via p38 binding and activation depending on oxygen signal

Xin Xin Xiong, Feng Pan, Ruo Qiao Chen, Dian Xing Hu, Xin Yao Qiu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0260-8

Abstract | Full Text

Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis

Huan Jing, Xiaoxia Su, Bo Gao, Yi Shuai, Ji Chen et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0231-0

Abstract | Full Text

14-3-3? delivered by hepatocellular carcinoma-derived exosomes impaired anti-tumor function of tumor-infiltrating T lymphocytes

Xiaochen Wang, Haiyuan Shen, Guangyan Zhangyuan, Ruyi Huang, Wenjie Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0180-7

Abstract | Full Text

Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence

Jing Wang, Yiji Feng, Peng Han, Fenghua Wang, Xueting Luo et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0200-7

Abstract | Full Text

UHRF1 depletion sensitizes retinoblastoma cells to chemotherapeutic drugs via downregulation of XRCC4

Heng He, Chunsik Lee & Jong Kyong Kim

Cell Death & Disease 2018 9: 10.1038/s41419-017-0203-4

Abstract | Full Text

Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2

Xin Zhang, Xiuting Liu, Wei Zhou, Mengdi Yang, Yang Ding et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0251-9

Abstract | Full Text

The binding landscape of a partially-selective isopeptidase inhibitor with potent pro-death activity, based on the bis(arylidene)cyclohexanone scaffold

Sonia Ciotti, Riccardo Sgarra, Andrea Sgorbissa, Carlotta Penzo, Andrea Tomasella et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0259-1

Abstract | Full Text

ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells

Ching-Wen Chang, Yu-Syuan Chen, Yeou-Guang Tsay, Chia-Li Han, Yu-Ju Chen et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0250-x

Abstract | Full Text

PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver


Cell Death & Disease 2018 9: 10.1038/s41419-017-0228-8

Abstract | Full Text

Osteoblast-targeted delivery of miR-33-5p attenuates osteopenia development induced by mechanical unloading in mice

Han Wang, Zebing Hu, Fei Shi, Jingjing Dong, Lei Dang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0210-5

Abstract | Full Text

The antitumor natural product tanshinone IIA inhibits protein kinase C and acts synergistically with 17-AAG

Chao Lv, Hua-Wu Zeng, Jin-Xin Wang, Xing Yuan, Chuang Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0247-5

Abstract | Full Text

Evaluation of autophagy inducers in epithelial cells carrying the ?F508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR

Shaoyi Zhang, Gautier Stoll, José Manuel Bravo San Pedro, Valentina Sica, Allan Sauvat et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0235-9

Abstract | Full Text

Genome-wide DNA methylation analysis reveals that mouse chemical iPSCs have closer epigenetic features to mESCs than OSKM-integrated iPSCs

Wangfang Ping, Jian Hu, Gongcheng Hu, Yawei Song, Qing Xia et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0234-x

Abstract | Full Text

EZH2 inhibits autophagic cell death of aortic vascular smooth muscle cells to affect aortic dissection

Rui Li, Xin Yi, Xiang Wei, Bo Huo, Xian Guo et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0213-2

Abstract | Full Text

MicroRNA-27a-5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis

Daniela Barros-Silva, Pedro Costa-Pinheiro, Henrique Duarte, Elsa Joana Sousa, Adriane Feijó Evangelista et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0241-y

Abstract | Full Text

miR-195 targets cyclin D3 and survivin to modulate the tumorigenesis of non-small cell lung cancer

Xiaojie Yu, Yiqiang Zhang, David Cavazos, Xiuye Ma, Zhenze Zhao et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0219-9

Abstract | Full Text

MicroRNA-1253 suppresses cell proliferation and invasion of non-small-cell lung carcinoma by targeting WNT5A

Meiyue Liu, Yue Zhang, Jie Zhang, Haifeng Cai, Chao Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0218-x

Abstract | Full Text

Antitumor activity of EGFR-specific CAR T cells against non-small-cell lung cancer cells in vitro and in mice

He Li, Yao Huang, Du-Qing Jiang, Lian-Zhen Cui, Zhou He et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0238-6

Abstract | Full Text

Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis

Xianxian Wu, Haiying Zhang, Wei Qi, Ying Zhang, Jiamin Li et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0257-3

Abstract | Full Text

Role of c-Abl and nephrin in podocyte cytoskeletal remodeling induced by angiotensin II

Yiqiong Ma, Qian Yang, Zhentong Zhong, Wei Liang, Lu Zhang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0225-y

Abstract | Full Text

circHIPK3 regulates cell proliferation and migration by sponging miR-124 and regulating AQP3 expression in hepatocellular carcinoma

Genwen Chen, Yanting Shi, Mengmeng Liu & Jianyong Sun

Cell Death & Disease 2018 9: 10.1038/s41419-017-0204-3

Abstract | Full Text

Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo

Kangmao Huang, Yanyan Chen, Rui Zhang, Yizheng Wu, Yan Ma et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0166-5

Abstract | Full Text

Notch1 is a prognostic factor that is distinctly activated in the classical and proneural subtype of glioblastoma and that promotes glioma cell survival via the NF-?B(p65) pathway

Long Hai, Chen Zhang, Tao Li, Xingchen Zhou, Bo Liu et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0119-z

Abstract | Full Text

TRIM36, a novel androgen-responsive gene, enhances anti-androgen efficacy against prostate cancer by inhibiting MAPK/ERK signaling pathways

Chao Liang, Shangqian Wang, Chao Qin, Meilin Bao, Gong Cheng et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0197-y

Abstract | Full Text

Mesenchymal stem cells over-expressing cxcl12 enhance the radioresistance of the small intestine

Pengyu Chang, Boyin Zhang, Lihong Shao, Wei Song, Weiyan Shi et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0222-1

Abstract | Full Text

Ubiquitin-specific protease 4 promotes hepatocellular carcinoma progression via cyclophilin A stabilization and deubiquitination

Tianyi Li, Bin Yan, Yang Ma, Junyong Weng, Shouwen Yang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0182-5

Abstract | Full Text

Game-changing restraint of Ros-damaged phenylalanine, upon tumor metastasis

Geraldine Gueron, Nicolás Anselmino, Paula Chiarella, Emiliano G. Ortiz, Sofia Lage Vickers et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0147-8

Abstract | Full Text

Clinorotation-induced autophagy via HDM2-p53-mTOR pathway enhances cell migration in vascular endothelial cells

Cheng-Fei Li, Jia-Xing Sun, Yuan Gao, Fei Shi, Yi-Kai Pan et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0185-2

Abstract | Full Text

SMAD4 feedback regulates the canonical TGF-ß signaling pathway to control granulosa cell apoptosis


Cell Death & Disease 2018 9: 10.1038/s41419-017-0205-2

Abstract | Full Text

The MiR-135b–BMAL1–YY1 loop disturbs pancreatic clockwork to promote tumourigenesis and chemoresistance

Weiliang Jiang, Senlin Zhao, Jia Shen, Lihong Guo, Yi Sun et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0233-y

Abstract | Full Text

Inactivation of ribosomal protein S27-like confers radiosensitivity via the Mdm2-p53 and Mdm2–MRN–ATM axes


Cell Death & Disease 2018 9: 10.1038/s41419-017-0192-3

Abstract | Full Text

Cooperation between Hsp90 and mortalin/GRP75 in resistance to cell death induced by complement C5b-9


Cell Death & Disease 2018 9: 10.1038/s41419-017-0240-z

Abstract | Full Text

Nicotine associated breast cancer in smokers is mediated through high level of EZH2 expression which can be reversed by methyltransferase inhibitor DZNepA

Kanchan Kumari, Biswajit Das, Amit Adhya, Sanjib Chaudhary, Shantibhusan Senapati et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0224-z

Abstract | Full Text

YAP triggers the Wnt/ß-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury

Feihong Deng, Liang Peng, Zhijun Li, Gao Tan, Erbo Liang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0244-8

Abstract | Full Text

Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe

Silvia Pietrobono, Roberta Santini, Sinforosa Gagliardi, Francesca Dapporto, David Colecchia et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0142-0

Abstract | Full Text

IL-6 potentiates BMP-2-induced osteogenesis and adipogenesis via two different BMPR1A-mediated pathways

Ru-Lin Huang, Yangbai Sun, Chia-Kang Ho, Kai Liu, Qi-Qun Tang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0126-0

Abstract | Full Text

Upregulation of kinesin family member 4A enhanced cell proliferation via activation of Akt signaling and predicted a poor prognosis in hepatocellular carcinoma

Yanlin Huang, Hongbo Wang, Yifan Lian, Xiaojuan Wu, Liang Zhou et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0114-4

Abstract | Full Text

Mixed lineage kinase ZAK promotes epithelial–mesenchymal transition in cancer progression

Linna Li, Ning Su, Ting Zhou, Dayong Zheng, Zheng Wang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0161-x

Abstract | Full Text

RAP80 is an independent prognosis biomarker for the outcome of patients with esophageal squamous cell carcinoma

Qingyuan Yang, Wanrun Lin, Zhiwei Liu, Jiabei Zhu, Nan Huang et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0177-2

Abstract | Full Text



Organellar stress intersects the astrocyte endoplasmic reticulum, mitochondria and nucleolus in HIV associated neurodegeneration

Shruthi Nooka & Anuja Ghorpade

Cell Death & Disease 2018 9: 10.1038/s41419-018-0341-3

Abstract | Full Text

NDRG2 programs tumor-associated macrophages for tumor support

Silvia von Karstedt

Cell Death & Disease 2018 9: 10.1038/s41419-018-0268-8

Abstract | Full Text

Heterogeneity and cell fate flux in single human pancreatic islet cells

Natasha H. J. Ng & Adrian K. K. Teo

Cell Death & Disease 2018 9: 10.1038/s41419-018-0269-7

Abstract | Full Text

Beclin1 circulating levels and accelerated aging markers in COPD

Frédéric Schlemmer, Laurent Boyer, Thibaud Soumagne, Audrey Ridoux, Christos Chouaid et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0178-1

Abstract | Full Text

Review Article


Hints on ATGL implications in cancer: beyond bioenergetic clues

Rolando Vegliante, Luca Di Leo, Fabio Ciccarone & Maria Rosa Ciriolo

Cell Death & Disease 2018 9: 10.1038/s41419-018-0345-z

Abstract | Full Text

CAR-T cells: the long and winding road to solid tumors


Cell Death & Disease 2018 9: 10.1038/s41419-018-0278-6

Abstract | Full Text

Long non-coding RNAs in ischemic stroke

Mei-Hua Bao, Vivian Szeto, Burton B. Yang, Shu-zhen Zhu, Hong-Shuo Sun et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0282-x

Abstract | Full Text

The carnitine system and cancer metabolic plasticity

Melone Mariarosa Anna Beatrice, Valentino Anna, Margarucci Sabrina, Galderisi Umberto, Giordano Antonio et al.

Cell Death & Disease 2018 9: 10.1038/s41419-018-0313-7

Abstract | Full Text

Targeting deubiquitinase USP28 for cancer therapy

Xiaofang Wang, Zhiyi Liu, Li Zhang, Zhaozhi Yang, Xingxing Chen et al.

Cell Death & Disease 2018 9: 10.1038/s41419-017-0208-z

Abstract | Full Text

Meeting Report


Meeting Report: The 8th Barossa Meeting—Cell Signaling in Cancer Medicine in the Barossa Valley, Australia

Guillermo A. Gomez, Joanna M. Woodcock, Vinay Tergaonkar & Philip A. Gregory

Cell Death & Disease 2018 9: 10.1038/s41419-018-0285-7

Abstract | Full Text

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