We bring you the latest news from the healthcare about the health care in the United Kingdom.

vrijdag 9 februari 2018

Nature Reviews Endocrinology - Table of Contents alert Volume 14 Issue 3

If you are unable to see the message below, click here to view.
Nature Reviews Endocrinology

Do you have a career question? 

The Naturejobs podcast features one-on-one Q&As, panel discussions and other exclusive content to help scientists with their careers. Hosted on the Naturejobs blog, the podcast is also available on iTunes and Soundcloud. 

Listen today!
March 2018 Volume 14 Number 3 Advertisement
Nature Reviews Endocrinology cover
2016 2-year Impact Factor 18.318
Journal Metrics 2-year Median 13
In this issue
Research Highlights
News and Views
Also this month
 Featured article:
Animal models of obesity and diabetes mellitus
Maximilian Kleinert, Christoffer Clemmensen, Susanna M. Hofmann, Mary C. Moore, Simone Renner, Stephen C. Woods, Peter Huypens, Johannes Beckers, Martin Hrabe de Angelis, Annette Schürmann, Mostafa Bakhti, Martin Klingenspor, Mark Heiman, Alan D. Cherrington, Michael Ristow, Heiko Lickert, Eckhard Wolf, Peter J. Havel, Timo D. Müller & Matthias H. Tschöp

Nature Research ‘lab health’ survey 2018

The Nature Research’s lab health survey aims to find out what makes a research group supportive, productive, and rigorous. The survey should take 10 to 15 minutes to complete and you’ll have the chance to win a £100/$150 Amazon gift card. Your entries will be confidential and results will be featured in Nature

Complete the survey today >> 

Recommend to library

Gene therapy: Autoimmune diabetes reversed in mice
Published online: 19 January 2018
p127 | doi:10.1038/nrendo.2018.4


Adipose tissue: New tissue processing technique for adipose tissues
Published online: 29 January 2018
p128 | doi:10.1038/nrendo.2018.8


Risk factors: Breastfeeding reduces risk of type 2 diabetes mellitus
Published online: 29 January 2018
p128 | doi:10.1038/nrendo.2018.9


Neuropsychiatric disorders: Side effects of olanzapine worsened by metabolic dysfunction
Published online: 29 December 2017
p129 | doi:10.1038/nrendo.2017.183


Osteoporosis: Community-based screening reduces hip fracture risk
Published online: 19 January 2018
p129 | doi:10.1038/nrendo.2018.2


Metabolism: Leptin's role in starvation
Published online: 19 January 2018
p129 | doi:10.1038/nrendo.2018.6


Reproductive endocrinology: Hypoxia in endometrial repair
Published online: 02 February 2018
p130 | doi:10.1038/nrendo.2018.12


Adipose tissue: Bile acid-TGR5 axis promotes beiging
Published online: 02 February 2018
p130 | doi:10.1038/nrendo.2018.13



Diabetes: Towards a coxsackievirus B-based vaccine to combat T1DM
Didier Hober & Enagnon Kazali Alidjinou

Published online: 12 January 2018
p131 | doi:10.1038/nrendo.2017.184

The role of group B coxsackieviruses (CVB) in the pathogenesis of type 1 diabetes mellitus (T1DM) remains controversial. A recent report by Stone et al. showed that a CVB1-based vaccine can protect against both CVB1 infection and CVB1-induced T1DM in mouse models. This tool could help to elucidate the relationship between CVB and T1DM.
Full Text | PDF

Adipose tissue: The dysfunctional adipocyte — a cancer cell's best friend
Zhuzhen Zhang & Philipp E. Scherer

Published online: 05 January 2018
p132 | doi:10.1038/nrendo.2017.174

The interactions of adipocytes with tumour cells have been extensively scrutinized. The adipocyte's mitogenic influence on tumour cells is attributed to several hormonal, growth factor and adipokine effects. A recent study has expanded our understanding of how adipocytes promote tumour progression by demonstrating that adipocytes actively catabolize the chemotherapeutic agent daunorubicin.
Full Text | PDF

Diabetes: Quantifying genetic susceptibility in T1DM — implications for diagnosis after age 30
Everett Meyer & David M. Maahs

Published online: 09 February 2018
p134 | doi:10.1038/nrendo.2018.7

Treatment of type 1 diabetes mellitus (T1DM) for individuals over the age of 30 years is often delayed. A recent large-scale population analysis used a genetic risk score to define T1DM in the first six decades of life, providing specific insights applicable to those >30 years of age.
Full Text | PDF

Thyroid cancer: Balancing benefit and risk in TSH management of DTC
Frederik A. Verburg & Markus Luster

Published online: 19 January 2018
p136 | doi:10.1038/nrendo.2018.1

TSH-suppressive therapy and the increased risk of cardiovascular disease in patients with differentiated thyroid cancer (DTC) was previously reported. A recent study by Pajamaki and colleagues found that patients with DTC have a higher risk of atrial fibrillation but a lower all-cause cardiovascular death rate. This study offers insights into this effect.
Full Text | PDF

Adrenal disease: Imitating the cortisol profile improves the immune system
Lisa Muller & Marcus Quinkler

Published online: 19 January 2018
p137 | doi:10.1038/nrendo.2018.5

A once-daily, modified-release hydrocortisone medication reduces BMI and improves glucose metabolism compared with the twice- or thrice-daily standard hydrocortisone treatment in patients with adrenal insufficiency. Now, further evidence emerges that changing to a once-daily, modified-release hydrocortisone medication improves the immune cell profile and results in fewer infections.
Full Text | PDF

 npj Breast Cancer is an online-only, open access, multidisciplinary journal dedicated to publishing high-quality original research articles, reviews, editorials, commentaries, and hypothesis generating observations on all areas of breast cancer research. All content from the journal is now included in PubMed Central and PubMed. Part of the Nature Partner Journal series, the journal is published in partnership with the Breast Cancer Research Foundation.

Explore all articles here >>>
Animal models of obesity and diabetes mellitus
Maximilian Kleinert et al.

Published online: 19 January 2018
p140 | doi:10.1038/nrendo.2017.161

Animal models are necessary for the discovery, validation and optimization of novel therapeutics. Here, Matthias Tschop and colleagues consolidate the key information on the currently available animal models of obesity and diabetes mellitus and highlight the advantages, limitations and important caveats of each of these models.
Abstract | Full Text | PDF

Emerging nonmetabolic functions of skin fat
Christian F. Guerrero-Juarez & Maksim V. Plikus

Published online: 12 January 2018
p163 | doi:10.1038/nrendo.2017.162

Dermal white adipose tissue (dWAT) has evolved novel features that are central to skin physiology. Here, Christian Guerrero-Juarez and Maksim Plikus discuss the close connectivity between dWAT and cycling hair follicles and how, by responding to multiple hair-derived signals, dWAT periodically cycles itself.
Abstract | Full Text | PDF

Osteocalcin in the brain: from embryonic development to age-related decline in cognition
Arnaud Obri, Lori Khrimian, Gerard Karsenty & Franck Oury

Published online: 29 January 2018
p174 | doi:10.1038/nrendo.2017.181

The bone-derived hormone osteocalcin is not only involved with energy metabolism but is also necessary for brain development and function in mice. This Review discusses the role of osteocalcin in the regulation of cognitive function in the mouse brain and potential therapeutic opportunities.
Abstract | Full Text | PDF

Long-term effects of adolescent obesity: time to act
Thomas Reinehr

Published online: 24 November 2017
p183 | doi:10.1038/nrendo.2017.147

The incidence of adolescent obesity is increasing, which has serious long-term implications for the affected individuals and wider society. Here, Thomas Reinehr outlines the effects of adolescent obesity and discusses how the epidemic could be addressed.
Abstract | Full Text | PDF

nature events
Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here.

Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com
More Nature Events
Nature Reviews Endocrinology was previously published as Nature Clinical Practice Endocrinology & Metabolism.

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/myaccount
(You will need to log in to be recognised as a nature.com registrant).

For further technical assistance, please contact our registration department

For print subscription enquiries, please contact our subscription department

For other enquiries, please contact our feedback department

Springer Nature | One New York Plaza, Suite 4500 | New York | NY 10004-1562 | USA

Springer Nature's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne
San Diego - San Francisco - Washington - New York - Boston

Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at The Campus, 4 Crinan Street, London, N1 9XW.

© 2018 Macmillan Publishers Limited, part of Springer Nature. All Rights Reserved.

Springer Nature