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woensdag 24 januari 2018

Nature Reviews Rheumatology - Table of Contents alert Volume 14 Issue 2

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2016 2-year Impact Factor 12.188 Journal Metrics 2-year Median 7
In this issue
Research Highlights
Year in Review
Also this month
 Featured article:
Moving towards a molecular taxonomy of autoimmune rheumatic diseases
Guillermo Barturen, Lorenzo Beretta, Ricard Cervera, Ronald Van Vollenhoven & Marta E. Alarcón-Riquelme

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Systemic sclerosis: Promoting apoptosis is key to reversing fibrosis
Published online: 24 January 2018
p61 | doi:10.1038/nrrheum.2017.222


Acute inflammatory arthritis: Long-term effects of chikungunya
Published online: 24 January 2018
p62 | doi:10.1038/nrrheum.2017.223


Autoinflammatory diseases: TNF drives cryopyrinopathies in mice
Published online: 03 January 2018
p63 | doi:10.1038/nrrheum.2017.217


Rheumatoid arthritis: IFNγ drives synovial tissue remodelling
Published online: 11 January 2018
p63 | doi:10.1038/nrrheum.2017.221


Experimental arthritis: Anti-TNF kills the macrophage response
Published online: 24 January 2018
p64 | doi:10.1038/nrrheum.2017.207


Inflammation: Potassium channel regulates osteoclastogenesis
Published online: 24 January 2018
p64 | doi:10.1038/nrrheum.2018.7




Osteoarthritis: Arthroscopy does not delay TKA for knee OA | Therapy: Biologics and risk of second malignant neoplasm | Rheumatoid arthritis: Higher disease risk in children of women with RA | Systemic lupus erythematosus: Rituximab improves SLE disease activity

Nature Reviews Rheumatology
JOBS of the week
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The Ohio State University Comprehensive Cancer Center and Colleage of Medicine
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Benaroya Research Institute at Virginia Mason (BRI)
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Open Rank, Term Tenure Track
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Nature Reviews Rheumatology
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Amsterdam, Netherlands
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Inflammation in 2017: Connectivity to other fields brings new ideas
Pierre Miossec

Published online: 11 January 2018
p65 | doi:10.1038/nrrheum.2017.215

Multiple scientific fields pertaining to inflammation, including the fields of cardiovascular, infection and cancer research, are increasingly contributing to our understanding of rheumatoid arthritis (RA). In 2017, such research has helped develop our understanding of RA comorbidity, the link between RA pathogenesis and infection, and the effects of new therapies.
Full Text | PDF

Osteoporosis in 2017: Addressing the crisis in the treatment of osteoporosis
Christian Roux & Karine Briot

Published online: 11 January 2018
p67 | doi:10.1038/nrrheum.2017.218

A large number of patients with osteoporosis are not receiving appropriate treatment, due in part to concerns regarding drug safety. Great progress has been made to address this crisis in therapy in 2017, including highlighting the patients' views, developing new therapies and treatment strategies and addressing these safety concerns.
Full Text | PDF

Paediatric rheumatology in 2017: Child-centred research is the key to progress
Michael W. Beresford & Athimalaipet V. Ramanan

Published online: 11 January 2018
p69 | doi:10.1038/nrrheum.2017.214

The rarity, severity and complexity of paediatric rheumatic diseases make progress in treating these diseases a challenge. In 2017, a new series of recommendations for treatment, studies that unravel the complexity of juvenile idiopathic arthritis and clinical trials that tackle sight-threatening uveitis have helped to improve paediatric care.
Full Text | PDF

Rheumatoid arthritis in 2017: Protective dietary and hormonal factors brought to light
Jeffrey A. Sparks & Karen H. Costenbader

Published online: 11 January 2018
p71 | doi:10.1038/nrrheum.2017.216

Tremendous progress has been made in the identification of rheumatoid arthritis (RA) risk factors in 2017. The results of epidemiological studies highlighted dietary and hormonal factors that are associated with slowing the transition from one preclinical phase of RA to another, potentially protecting individuals from developing RA.
Full Text | PDF

Osteoarthritis in 2017: Latest advances in the management of knee OA
Timothy E. McAlindon & Raveendhara R. Bannuru

Published online: 11 January 2018
p73 | doi:10.1038/nrrheum.2017.219

Osteoarthritis research in 2017 provided new insights into the long-term effects of intra-articular glucocorticoids, and also led to the approval of a novel, longer-lasting glucocorticoid formulation. New drugs for the treatment of osteoarthritis also emerged this year, including a small-molecule inhibitor of the Wnt signalling pathway.
Full Text | PDF

Moving towards a molecular taxonomy of autoimmune rheumatic diseases
Guillermo Barturen, Lorenzo Beretta, Ricard Cervera, Ronald Van Vollenhoven & Marta E. Alarcón-Riquelme

Published online: 24 January 2018
p75 | doi:10.1038/nrrheum.2017.220

The heterogeneity of autoimmune rheumatic diseases, and their shared clinical and molecular features, makes classifying and diagnosing these diseases difficult and highlights the need for a new taxonomy. Reclassifying these diseases according to the underlying molecular mechanisms might lead to novel insights into disease mechanisms and enable better patient stratification.
Abstract | Full Text | PDF | Supplementary information

Targeting lymphatic function as a novel therapeutic intervention for rheumatoid arthritis
Echoe M. Bouta, Richard D. Bell, Homaira Rahimi, Lianping Xing, Ronald W. Wood, Clifton O. Bingham III, Christopher T. Ritchlin & Edward M. Schwarz

Published online: 11 January 2018
p94 | doi:10.1038/nrrheum.2017.205

Preclinical studies suggest that the lymphatic system has a critical role in the pathogenesis and therapy of inflammatory-erosive arthritis. These findings, and complementary data from human studies, highlight the translational potential of assessing and modulating the lymphatic system in patients with chronic arthritis.
Abstract | Full Text | PDF | Supplementary information

Behçet syndrome: a contemporary view
Hasan Yazici, Emire Seyahi, Gulen Hatemi & Yusuf Yazici

Published online: 03 January 2018
p107 | doi:10.1038/nrrheum.2017.208

In this Review, the authors discuss the emerging evidence of the aetiology of Behçet's. They argue that geographical variation in prevalence, variation in disease expression and evidence of clinical subsets supports the notion that Behçet's is a syndrome rather than a disease.
Abstract | Full Text | PDF

Corrigendum: Behçet syndrome: a contemporary view
Hasan Yazici, Emire Seyahi, Gulen Hatemi & Yusuf Yazici

Published online: 24 January 2018
p119 | doi:10.1038/nrrheum.2018.3

Full Text | PDF
Corrigendum: The RA-MAP Consortium: a working model for academia-industry collaboration
Andrew P. Cope, Michael R. Barnes, Alexandra Belson, Michael Binks, Sarah Brockbank, Francisco Bonachela-Capdevila, Claudio Carini, Benjamin A. Fisher, Carl S. Goodyear, Paul Emery, Michael R. Ehrenstein, Neil Gozzard, Ray Harris, Sally Hollis, Sarah Keidel, Marc Levesque, Catharina Lindholm, Michael F. McDermott, Iain B. McInnes, Christopher M. Mela, Gerry Parker, Simon Read, Ayako Wakatsuki Pedersen, Frederique Ponchel, Duncan Porter, Ravi Rao, Anthony Rowe, Peter Schulze-Knappe, Matthew A. Sleeman, Deborah Symmons, Peter C. Taylor, Brian Tom, Wayne Tsuji, Denny Verbeeck, John D. Isaacs & The RA-MAP Consortium

Published online: 24 January 2018
p119 | doi:10.1038/nrrheum.2018.6

Full Text | PDF
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Nature Reviews Rheumatology was previously published as Nature Clinical Practice Rheumatology.

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