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Journal of Antibiotics - Table of Contents alert Volume 71 Issue 1

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The Journal of Antibiotics

Special Issue Dedicated to Hamao Umezawa: In memory of Professor Umezawa on the occasion of the 60th anniversary of global kanamycin marketing

The January issue of The Journal of Antibiotics is dedicated to Professor Hamao Umezawa on the occasion of the 60th anniversary of global kanamycin marketing. He was a board member of The Journal of Antibiotics from its first issue in 1947 until his death in 1986 and contributed to it gaining its reputation as a leading international journal.
We would like to thank his friends and followers who contributed to this special issue, as well as Managing Editor Dr. Yoshikazu Takahashi and Dr. Manabu Kawada for planning and coordinating this issue.

The Journal of Antibiotics

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Volume 71, Issue 1 (January 2018)

In this issue
Review Articles
Original Articles
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Preface: special issue Hamao Umezawa (1914–1986)

Kuniaki Tatsuta, Yoshikazu Takahashi& Manabu Kawada

The Journal of Antibiotics 2018 71: 1; January 05, 2018; 10.1038/ja.2017.136


Abstract | Full Text

Memory of Professor Hamao Umezawa

Masakatsu Shibasaki & Katsuhisa Yamazaki

The Journal of Antibiotics 2018 71: 2 - 3; January 05, 2018; 10.1038/ja.2017.137


Abstract | Full Text

Review Articles

Destination of aminoglycoside antibiotics in the 'post-antibiotic era'

Yoshiaki Takahashi & Masayuki Igarashi

The Journal of Antibiotics 2017 71: 4 - 14; October 25, 2017; 10.1038/ja.2017.117


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New antituberculous drugs derived from natural products: current perspectives and issues in antituberculous drug development

Masayuki Igarashi, Yoshimasa Ishizaki& Yoshiaki Takahashi

The Journal of Antibiotics 2017 71: 15 - 25; November 01, 2017; 10.1038/ja.2017.126


Abstract | Full Text

Our microbes not only produce antibiotics, they also overproduce amino acids

Sergio Sanchez, Romina Rodríguez-Sanoja, Allison Ramos& Arnold L Demain

The Journal of Antibiotics 2017 71: 26 - 36; November 01, 2017; 10.1038/ja.2017.142


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Professor Hamao Umezawa opened up a new road for the development of molecularly targeted therapeutic drugs for cancers

Masaya Imoto

The Journal of Antibiotics 2017 71: 37 - 38; November 01, 2017; 10.1038/ja.2017.139


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Novel approaches for identification of anti-tumor drugs and new bioactive compounds

Manabu Kawada, Sonoko Atsumi, Shun-ichi Wada& Shuichi Sakamoto

The Journal of Antibiotics 2017 71: 39 - 44; August 30, 2017; 10.1038/ja.2017.97


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Current landscape and future prospects of antiviral drugs derived from microbial products

Naoki Takizawa & Manabu Yamasaki

The Journal of Antibiotics 2017 71: 45 - 52; October 11, 2017; 10.1038/ja.2017.115


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Synthetic studies of viridiofungins, broad-spectrum antifungal agents and serine palmitoyl transferase inhibitors

Naoya Kumagai & Masakatsu Shibasaki

The Journal of Antibiotics 2017 71: 53 - 59; September 27, 2017; 10.1038/ja.2017.110


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Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology

Hayamitsu Adachi, Koichi Nakae, Shuichi Sakamoto, Chisato Nosaka, Sonoko Atsumi et al.

The Journal of Antibiotics 2017 71: 60 - 71; November 01, 2017; 10.1038/ja.2017.138


Abstract | Full Text

Autophagy-regulating protease Atg4: structure, function, regulation and inhibition

Tatsuro Maruyama & Nobuo N Noda

The Journal of Antibiotics 2017 71: 72 - 78; September 13, 2017; 10.1038/ja.2017.104


Abstract | Full Text

Original Articles

In vivo efficacy of ß-lactam/tripropeptin C in a mouse septicemia model and the mechanism of reverse ß-lactam resistance in methicillin-resistant Staphylococcus aureus mediated by tripropeptin C

Hideki Hashizume, Yoshiaki Takahashi, Tohru Masuda, Shun-ichi Ohba, Tomokazu Ohishi et al.

The Journal of Antibiotics 2017 71: 79 - 85; July 26, 2017; 10.1038/ja.2017.88


Abstract | Full Text

Biological activity of intervenolin analogs with a phenyl substituent

Hikaru Abe, Manabu Kawada, Masayuki Igarashi, Shun-ichi Ohba, Chigusa Hayashi et al.

The Journal of Antibiotics 2017 71: 86 - 90; October 11, 2017; 10.1038/ja.2017.123


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Quadoctomycin, a 48-membered macrolide antibiotic from Streptomyces sp. MM168-141F8

Ryuichi Sawa, Yumiko Kubota, Maya Umekita, Masaki Hatano, Chigusa Hayashi et al.

The Journal of Antibiotics 2017 71: 91 - 96; November 15, 2017; 10.1038/ja.2017.140


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Engineered production and evaluation of 6'-deoxy-tallysomycin H-1 revealing new insights into the structure–activity relationship of the anticancer drug bleomycin


The Journal of Antibiotics 2017 71: 97 - 103; August 23, 2017; 10.1038/ja.2017.93


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Synthesis and antibacterial activity of novel lincomycin derivatives. III. Optimization of a phenyl thiadiazole moiety

Ko Kumura, Yoshinari Wakiyama, Kazutaka Ueda, Eijiro Umemura, Takashi Watanabe et al.

The Journal of Antibiotics 2017 71: 104 - 112; July 05, 2017; 10.1038/ja.2017.59


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Self-control of the PHO regulon: the PhoP-dependent protein PhoU controls negatively expression of genes of PHO regulon in Streptomyces coelicolor

Seomara Martín-Martín, Antonio Rodríguez-García, Fernando Santos-Beneit, Etelvina Franco-Domínguez, Alberto Sola-Landa et al.

The Journal of Antibiotics 2017 71: 113 - 122; November 01, 2017; 10.1038/ja.2017.130


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Wakodecalines A and B, new decaline metabolites isolated from a fungus Pyrenochaetopsis sp. RK10-F058

Toshihiko Nogawa, Naoki Kato, Takeshi Shimizu, Akiko Okano, Yushi Futamura et al.

The Journal of Antibiotics 2017 71: 123 - 128; September 13, 2017; 10.1038/ja.2017.103


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Valgamicin C, a novel cyclic depsipeptide containing the unusual amino acid cleonine, and related valgamicins A, T and V produced by Amycolatopsis sp. ML1-hF4

Hideki Hashizume, Kiyoko Iijima, Kazuma Yamashita, Tomoyuki Kimura, Shun-ichi Wada et al.

The Journal of Antibiotics 2017 71: 129 - 134; November 15, 2017; 10.1038/ja.2017.135


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A guanine derivative as a new MEK inhibitor produced by Streptomyces sp. MK63-43F2

Masatomi Iijima, Yuji Kubota, Ryuichi Sawa, Yumiko Kubota, Masaki Hatano et al.

The Journal of Antibiotics 2017 71: 135 - 138; September 06, 2017; 10.1038/ja.2017.100


Abstract | Full Text

Rakicidin F, a new antibacterial cyclic depsipeptide from a marine sponge-derived Streptomyces sp.

Shigeru Kitani, Tatsuya Ueguchi, Yasuhiro Igarashi, Kantinan Leetanasaksakul, Arinthip Thamchaipenet et al.

The Journal of Antibiotics 2017 71: 139 - 141; August 02, 2017; 10.1038/ja.2017.92


Abstract | Full Text

Cellular uptake of modified aminoglycosides

Kaivin Hadidi, Ezequiel Wexselblatt, Jeffrey D Esko& Yitzhak Tor

The Journal of Antibiotics 2017 71: 142 - 145; November 01, 2017; 10.1038/ja.2017.131


Abstract | Full Text

Ascosteroside D, a new mitochondrial respiration inhibitor discovered by pesticidal screening using insect ADP/ATP carrier protein-expressing Saccharomyces cerevisiae

Yoshihiro Watanabe, Yukihiro Asami, Satomi Narusawa, Shohei Hashimoto, Masato Iwatsuki et al.

The Journal of Antibiotics 2017 71: 146 - 148; October 11, 2017; 10.1038/ja.2017.118


Abstract | Full Text

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