We bring you the latest news from the healthcare about the health care in the United Kingdom. Do your have news for us? Contact the editor. Watch also this special movie.

dinsdag 10 oktober 2017

The Lancet: [Comment] Finding the right combination antiviral therapy for influenza

[Comment] Finding the right combination antiviral therapy for influenza
Influenza results in annual epidemics and global pandemics of acute respiratory illness that increases morbidity, mortality, and hospital admissions. Fortunately, there are currently two classes of antivirals licensed for the treatment of influenza in much of the world: the M2 inhibitiors (amantadine and rimantadine) and the neuraminidase inhibitors (oseltamivir, peramivir and zanamivir). There are also other antivirals licensed in Asia (laninamivir and favipiravir) and Russia (umifenovir). Additionally, a wide range of novel antivirals have been or are being studied in the treatment of influenza.
Read more

[Comment] Confirming cross-protection of bivalent HPV vaccine
Prophylactic human papillomavirus (HPV) vaccines have exceeded expectations in preventing infection with oncogenic HPV, the underlying cause of cervical cancer. Both the bivalent HPV vaccine and quadrivalent HPV vaccine contain virus-like particles that induce high-level antibody responses to HPV types 16 and 18, the two most oncogenic HPV types, which are responsible for 71% of cervical cancer cases globally.1 In the 11 years since their first licensure, the vaccines have been distributed globally in over 270 million doses and are demonstrably safe in population usage.
Read more

[Articles] Changes in the prevalence of human papillomavirus following a national bivalent human papillomavirus vaccination programme in Scotland: a 7-year cross-sectional study
Bivalent vaccination has led to a startling reduction in vaccine and cross-protective HPV types 7 years after vaccination. There is also evidence of herd protection against the vaccine-specific and cross-protective types in unvaccinated individuals born in 1995. These findings should be considered in cost-effectiveness models informing vaccine choice and models to shape the future of cervical screening programmes.
Read more

[Corrections] Corrections
Majumder MS, Nguyen CM, Mekaru SR, Brownstein JS. Yellow fever vaccination coverage heterogeneities in Luanda province, Angola. Lancet Infect Dis 2016; 16: 993–95—in the figure, the red square bullet should have read "threshold vaccination", and the blue circular bullet should have read "vaccinated to date". This correction has been made in the online version as of Oct 9, 2017.
Read more

[Articles] Ring vaccination with rVSV-ZEBOV under expanded access in response to an outbreak of Ebola virus disease in Guinea, 2016: an operational and vaccine safety report
The results show that a ring vaccination strategy can be rapidly and safely implemented at scale in response to Ebola virus disease outbreaks in rural settings.
Read more