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vrijdag 11 augustus 2017

Nature Reviews Endocrinology - Table of Contents alert Volume 13 Issue 9

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Nature Reviews Endocrinology

September 2017 Volume 13 Number 9
Nature Reviews Endocrinology cover
2016 2-year Impact Factor 18.318 Journal Metrics 2-year Median 13
In this issue
Research Highlights
News and Views

Also this month
 Featured article:
Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance
Ruth C. R. Meex & Matthew J. Watt
Recommend to library

Obesity: Olfactory senses linked to metabolism
Published online: 14 July 2017
p499 | doi:10.1038/nrendo.2017.94


Liver: Paradigm shift in the immunopathogenesis of NAFLD
Published online: 14 July 2017
p500 | doi:10.1038/nrendo.2017.95


Targeted therapies: Lenvatinib SELECTs survival benefit
Published online: 14 July 2017
p500 | doi:10.1038/nrendo.2017.96


Neuroendocrinology: Integrated stress response linked to TBI
Published online: 28 July 2017
p501 | doi:10.1038/nrendo.2017.102


Obesity: Gut microbiome and serum metabolome changes
Published online: 07 July 2017
p501 | doi:10.1038/nrendo.2017.89


Gut microbiota: Link between the gut and adipose tissues
Published online: 07 July 2017
p501 | doi:10.1038/nrendo.2017.92


Neuroendocrinology: Central insulin regulates eating behaviour
Published online: 04 August 2017
p502 | doi:10.1038/nrendo.2017.105


Growth and development: Dwarfism linked to hypertension treatment
Published online: 21 July 2017
p502 | doi:10.1038/nrendo.2017.98


Global Experts Meeting on diabetes and Endocrinology Conference
Melbourne, Australia
More science events from
Cardiovascular endocrinology: Is ANGPTL3 the next PCSK9?
Kiran Musunuru & Sekar Kathiresan
Published online: 14 July 2017
p503 | doi:10.1038/nrendo.2017.88
Recent reports suggest that molecular therapies targeting ANGPTL3 and its encoded protein angiopoietin-like protein 3 have clinical potential comparable to therapies targeting PCSK9 and its encoded protein proprotein convertase subtilisin/kexin type 9. By mainly affecting triglyceride-rich lipoproteins, ANGPTL3 inhibition might prove complementary to LDL cholesterol lowering with PCSK9 blockade.
Full Text | PDF
Obesity: Maternal obesity and congenital anomalies — risk and diagnosis
Jodie M. Dodd & Clare L. Whitehead
Published online: 04 August 2017
p504 | doi:10.1038/nrendo.2017.100
A new population-based observational cohort study involving more than 1.2 million live births highlights the increased risk of congenital anomalies with increasing degrees of maternal overweight and obesity. However, by only considering data on live-born infants, the full impact of maternal overweight and obesity on this aspect of reproductive and child health is underestimated.
Full Text | PDF
Bone cancer: Is the osteosarcoma genome targetable?
Sharon A. Savage & Lisa Mirabello
Published online: 04 August 2017
p506 | doi:10.1038/nrendo.2017.101
The osteosarcoma genome has long been known to be complex, with few common features between tumours. However, a growing number of somatic genome studies, including a recent study by Behjati et al., have identified common themes in subsets of these cancers. The data suggest that subsets of somatic signatures could be therapeutically tractable targets.
Full Text | PDF
Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance
Ruth C. R. Meex & Matthew J. Watt
Published online: 09 June 2017
p509 | doi:10.1038/nrendo.2017.56
In this Review, the authors describe the factors that influence the development of hepatic steatosis and discuss the evidence base that links steatosis to insulin resistance. They explore how steatosis alters the secretion of hepatokines from the liver, and how these secretome alterations regulate glucose metabolism and insulin action in non-hepatic tissues.
Abstract | Full Text | PDF
The gentle art of saying NO: how nitric oxide gets things done in the hypothalamus
Konstantina Chachlaki, John Garthwaite & Vincent Prevot
Published online: 16 June 2017
p521 | doi:10.1038/nrendo.2017.69
Vincent Prevot and colleagues discuss the role of neuronal nitric oxide (NO) in the regulation of key physiological processes controlled by the preoptic region of the hypothalamus, including reproduction. How deregulation of NO production might be involved in the pathophysiology of brain diseases, for which hormonal imbalances during postnatal development could be a risk factor, is also discussed.
Abstract | Full Text | PDF
Endocrine-disrupting chemicals and the regulation of energy balance
Angel Nadal et al.
Published online: 19 May 2017
p536 | doi:10.1038/nrendo.2017.51
Metabolism-disrupting chemicals (MDCs) are a subclass of endocrine-disrupting chemicals that affect energy homeostasis. Here, Angel Nadal and colleagues review the main mechanisms used by MDCs to alter energy balance, information that should help to identify new MDCs, as well as novel targets of their action.
Abstract | Full Text | PDF | Supplementary information
Type 2 diabetes mellitus and psychological stress — a modifiable risk factor
Ruth A. Hackett & Andrew Steptoe
Published online: 30 June 2017
p547 | doi:10.1038/nrendo.2017.64
Evidence suggests that psychological stress has a role in the aetiology of type 2 diabetes mellitus. Here, Hackett and Steptoe review the evidence and give an overview of intervention studies that have attempted to modify psychological or social factors to improve outcomes in patients with type 2 diabetes mellitus.
Abstract | Full Text | PDF
β-Cell mass versus function in type 1 diabetes mellitus: truth or dare?
Teresa Rodriguez-Calvo, Mark Atkinson & Matthias von Herrath
Published online: 07 July 2017
p1 | doi:10.1038/nrendo.2017.83

Full Text | PDF
Type 1 diabetes mellitus is a heterogeneous disease
Mikael Knip
Published online: 07 July 2017
p1 | doi:10.1038/nrendo.2017.84

Full Text | PDF
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*Journal Citation Reports, Thomson, 2016. Nature Reviews Endocrinology was previously published as Nature Clinical Practice Endocrinology & Metabolism.

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