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donderdag 22 juni 2017

Nature Reviews Rheumatology - Table of Contents alert Volume 13 Issue 7

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Nature Reviews Rheumatology

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July 2017 Volume 13 Number 7Advertisement
Nature Reviews Rheumatology cover
2016 2-year Impact Factor 12.188 Journal Metrics 2-year Median 7
In this issue
Research Highlights
News and Views

Also this month
 Featured article:
The role of IL-6 in host defence against infections: immunobiology and clinical implications
Stefan Rose-John, Kevin Winthrop & Leonard Calabrese

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Recommend to library

Autoimmunity: HLA-mediated protection in Goodpasture disease
Published online: 18 May 2017
p387 | doi:10.1038/nrrheum.2017.76


Osteoarthritis: Removing old chondrocytes to combat disease
Published online: 11 May 2017
p388 | doi:10.1038/nrrheum.2017.73


Immunology: Hippo signalling influences T cell fate
Published online: 25 May 2017
p389 | doi:10.1038/nrrheum.2017.82


Spondyloarthropathies: Gut-bone crosstalk in HLA-B27 rats
Published online: 01 June 2017
p389 | doi:10.1038/nrrheum.2017.89


Experimental arthritis: FLIPping the switch on macrophages
Published online: 01 June 2017
p390 | doi:10.1038/nrrheum.2017.90


Spondyloarthropathies: Targeting IL-17 in refractory PsA
Published online: 08 June 2017
p390 | doi:10.1038/nrrheum.2017.94



Spondyloarthropathies: Abatacept treatment for PsA | Autoinflammation: Canakinumab effective in HIDS treatment | Connective tissue diseases: Mycobacterial infection and Sjögren syndrome | Risk factors: Susceptibility allele identified in RHD

Nature Reviews Rheumatology
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Pharmacotherapy: Biosimilar switching — “To set a form upon desired change”
Jonathan Kay & Kevin L. Winthrop
Published online: 01 June 2017
p391 | doi:10.1038/nrrheum.2017.79
The highly anticipated NOR-SWITCH trial results provide valuable information for patients and physicians concerned about the effects of switching between a biologic agent and a biosimilar product. However, the possibility of frequent switches, potentially involving more than one biosimilar, raises more questions.
Full Text | PDF

Osteoarthritis: Nerve ablation — a new treatment for OA pain?
David A. Walsh
Published online: 01 June 2017
p393 | doi:10.1038/nrrheum.2017.78
Pain in osteoarthritis (OA) can be resistant to the medical and surgical treatments currently in use. Local denervation of the arthritic joint could offer a new approach to relieve OA pain, if the results of a new cryoneurolysis clinical trial are confirmed.
Full Text | PDF

Osteoarthritis: You can rely on radiography when managing OA, but not too much!
Ali Guermazi
Published online: 25 May 2017
p394 | doi:10.1038/nrrheum.2017.77
When considering the role of imaging in the management of symptomatic, peripheral joint osteoarthritis (OA) in clinical practice, clinicians should be aware that radiography has its drawbacks, and also consider that the use of advanced imaging techniques such as MRI should not be discouraged.
Full Text | PDF

Rheumatoid arthritis: Forward and reverse inheritance — the yin and the yang
J. Lee Nelson & Nathalie C. Lambert
Published online: 08 June 2017
p396 | doi:10.1038/nrrheum.2017.88
The theory of Mendelian inheritance states that half our genes are maternal and half are paternal. This view is incomplete, as maternal-fetal exchange creates a legacy of non-native cells within an individual that can affect their health for better or worse, including contributing to their risk of developing autoimmune disease.
Full Text | PDF

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The role of IL-6 in host defence against infections: immunobiology and clinical implications
Stefan Rose-John, Kevin Winthrop & Leonard Calabrese
Published online: 15 June 2017
p399 | doi:10.1038/nrrheum.2017.83
In this review, the authors discuss the role of IL-6 in the defence against infection, outlining insight gained from both preclinical and clinical studies, and examining the effects of IL-6-targeting therapies on immunocompetence and its clinical implications.
Abstract | Full Text | PDF

Pain in ankylosing spondylitis: a neuro-immune collaboration
Katayoon Bidad, Eric Gracey, Kasey S. Hemington, Josiane C. S. Mapplebeck, Karen D. Davis & Robert D. Inman
Published online: 15 June 2017
p410 | doi:10.1038/nrrheum.2017.92
In this Review, the authors summarize the different types of pain experienced by patients with ankylosing spondylitis, the underlying neurobiology and studies that are providing insights into the complex interplay between the immune system and neural pain-processing pathways.
Abstract | Full Text | PDF

The genetics revolution in rheumatology: large scale genomic arrays and genetic mapping
Stephen Eyre, Gisela Orozco & Jane Worthington
Published online: 01 June 2017
p421 | doi:10.1038/nrrheum.2017.80
This Review discusses the major insights gained from genetic studies in rheumatic diseases, such as genome-wide association studies, meta-analyses, fine-mapping and studies performed across different diseases and/or ethnicities, which have vastly increased our understanding of these diseases.
Abstract | Full Text | PDF

Why location matters — site-specific factors in rheumatic diseases
Caroline Ospelt & Mojca Frank-Bertoncelj
Published online: 15 June 2017
p433 | doi:10.1038/nrrheum.2017.96
Specific patterns of joint and organ involvement exist in different rheumatic diseases. Ospelt and Frank-Bertoncelj delve into the reasons behind these patterns, and what they mean for future research into rheumatic disease pathogenesis.
Abstract | Full Text | PDF

Managing rheumatic and musculoskeletal diseases — past, present and future
Gerd R. Burmester, Johannes W. J. Bijlsma, Maurizio Cutolo & Iain B. McInnes
Published online: 15 June 2017
p443 | doi:10.1038/nrrheum.2017.95
The field of rheumatology has seen remarkable progress in the past 70 years. This Perspectives article provides a concise overview of developments in the diagnosis and management of musculoskeletal rheumatic diseases, and what the future of rheumatology might hold.
Abstract | Full Text | PDF

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Nature Reviews Rheumatology was previously published as Nature Clinical Practice Rheumatology.

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