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woensdag 28 juni 2017

Nature Reviews Neurology - Table of Contents alert Volume 13 Issue 7

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Nature Reviews Neurology

Web collection: Parkinson disease 

2017 marks the 200th anniversary since James Parkinson published An Essay on the Shaking Palsy. To mark this event, Nature Reviews Disease Primers, Nature Reviews Neuroscience and Nature Reviews Neurology present this collection of articles about cutting-edge basic and clinical research into Parkinson disease.

Take a look at the collection
July 2017 Volume 13 Number 7

Nature Reviews Neurology cover
Impact Factor 20.257 Journal Metrics 2-year Median 15
In this issue
Research Highlights
News and Views

Also this month
 Featured article:
Imaging and fluid biomarkers in frontotemporal dementia
Lieke H. Meeter, Laura Donker Kaat, Jonathan D. Rohrer & John C. van Swieten

Recommend to library


Epilepsy: Cannabidiol reduces seizure frequency in Dravet syndrome
Published online: 09 June 2017
p383 | doi:10.1038/nrneurol.2017.86


In the news: Clinical trials excite at AAN 2017
Published online: 19 May 2017
p384 | doi:10.1038/nrneurol.2017.76


Dementia: Imaging signatures identified for dementia subtypes
Published online: 19 May 2017
p384 | doi:10.1038/nrneurol.2017.77


Neurodevelopmental disorders: Metformin — a therapeutic option for fragile X syndrome?
Published online: 02 June 2017
p384 | doi:10.1038/nrneurol.2017.82


Motor neuron disease: Proinflammatory monocytes might contribute to ALS progression
Published online: 12 May 2017
p385 | doi:10.1038/nrneurol.2017.74


Cerebrovascular malformations: Microbiota promotes cerebral cavernous malformations
Published online: 26 May 2017
p386 | doi:10.1038/nrneurol.2017.79


Alzheimer disease: Peripheral Aβ clearance — a therapeutic strategy for AD?
Published online: 26 May 2017
p386 | doi:10.1038/nrneurol.2017.80


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Stroke: Long-term outcome of endovascular therapy for ischaemic stroke
Charlotte Zerna & Mayank Goyal
Published online: 02 June 2017
p387 | doi:10.1038/nrneurol.2017.78
In patients with acute ischaemic stroke resulting from anterior circulation occlusion, endovascular therapy provides greater long-term benefits than does intravenous tissue plasminogen activator. However, further improvement of systems of care and research regarding adjunct therapies is still needed.
Full Text | PDF

Epilepsy: A new guideline on sudden unexpected death in epilepsy
Daniel Friedman
Published online: 09 June 2017
p388 | doi:10.1038/nrneurol.2017.83
The American Academy of Neurology and the American Epilepsy Society have jointly issued a new guideline on sudden expected death in epilepsy (SUDEP). The guideline emphasizes the importance of discussing SUDEP with patients and their caregivers, and uncovers gaps in the current literature that warrant further investigation.
Full Text | PDF

Call for nominations: 2017 John Maddox Prize for Standing up for Science.

Recognising the work of individuals who promote science in the face of hostility. Winners will be announced at a reception in London, as well as in Nature, and will receive £2,000.

Closing date for nominations is 31st July 2017.

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Autologous haematopoietic stem cell transplantation for treatment of multiple sclerosis
Paolo A. Muraro et al.
Published online: 16 June 2017
p391 | doi:10.1038/nrneurol.2017.81
Autologous haematopoietic stem cell transplantation has produced striking results in patients with aggressive multiple sclerosis in small trials. In this Review, Muraro et al. provide an overview of the procedure, detail evidence for its high efficacy in multiple sclerosis, and provide recommendations for its clinical use and future trials.
Abstract | Full Text | PDF

Imaging and fluid biomarkers in frontotemporal dementia
Lieke H. Meeter, Laura Donker Kaat, Jonathan D. Rohrer & John C. van Swieten
Published online: 16 June 2017
p406 | doi:10.1038/nrneurol.2017.75
Reliable biomarkers for frontotemporal dementia (FTD) are required for accurate discrimination between dementia types, prediction of clinical progression and tailoring of pharmacological interventions. This Review discusses the increasing number of available biomarkers for FTD — including novel imaging modalities and fluid biomarkers — and the future challenges in their implementation.
Abstract | Full Text | PDF

Modulators of microglial activation and polarization after intracerebral haemorrhage
Xi Lan et al.
Published online: 19 May 2017
p420 | doi:10.1038/nrneurol.2017.69
Effective drug treatments for intracerebral haemorrhage (ICH) are still lacking. However, therapies that target microglial phenotype switching might soon become available for affected patients. Here, Wang and colleagues summarize key advances in understanding of microglial function after ICH, including modulators of microglial function and interactions with other cells.
Abstract | Full Text | PDF

Drugging the pain epigenome
Ellen Niederberger, Eduard Resch, Michael J. Parnham & Gerd Geisslinger
Published online: 26 May 2017
p434 | doi:10.1038/nrneurol.2017.68
Chronic pain presents a major health burden, affecting more than 20% of adults worldwide, but currently available analgesics lack efficacy and/or are associated with severe adverse effects. Here, Ellen Niederberger and colleagues discuss epigenetic modulation as a new opportunity in pain-relief therapy, and consider the future challenges for the clinical development of these drugs.
Abstract | Full Text | PDF

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Nature Reviews Neurology was previously published as Nature Clinical Practice Neurology.

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