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vrijdag 10 maart 2017

Nature Reviews Endocrinology - Table of Contents alert Volume 13 Issue 4

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Nature Reviews Endocrinology

Poster on effects of new antidiabetic drugs on cardiovascular health

This poster summarizes cardiovascular outcome trials of newly developed glucose-lowering agents. Some of these drugs have shown cardiovascular benefit that might have clinical importance in the management of type 2 diabetes. 

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Supported by an educational grant from Novo Nordisk
April 2017 Volume 13 Number 4Advertisement
Nature Reviews Endocrinology cover
Impact Factor 15.432*
In this issue
Research Highlights
News and Views
Consensus Statement

Also this month
 Featured article:
Consensus Statement on next-generation-sequencing-based diagnostic testing of hereditary phaeochromocytomas and paragangliomas
The NGS in PPGL (NGSnPPGL) Study Group, Rodrigo A. Toledo, Nelly Burnichon, Alberto Cascon, Diana E. Benn, Jean-Pierre Bayley, Jenny Welander, Carli M. Tops, Helen Firth, Trish Dwight, Tonino Ercolino, Massimo Mannelli, Giuseppe Opocher, Roderick Clifton-Bligh, Oliver Gimm, Eamonn R. Maher, Mercedes Robledo, Anne-Paule Gimenez-Roqueplo & Patricia L. M. Dahia
Key Advances in Medicine eBook from Nature Reviews - FREE to download!

This essential resource summarizes the groundbreaking clinical and biomedical discoveries of 2016 and highlights the trends to watch out for in 2017, making it a must read eBook for anyone with an interest in medical science. 

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Adipose tissue: Apple or pear — waist-to-hip ratio and the risk of CHD and T2DM
Published online: 03 March 2017
p187 | doi:10.1038/nrendo.2017.26


Metabolism: Can BAT utilize dietary fatty acids?
Published online: 17 February 2017
p188 | doi:10.1038/nrendo.2017.18


Adipose tissue: Exosomal microRNAs — novel adipokines
Published online: 24 February 2017
p188 | doi:10.1038/nrendo.2017.22


Therapy: Potential therapy for severe insulin resistance
Published online: 10 February 2017
p189 | doi:10.1038/nrendo.2017.15


Autoimmunity: Death-defying β cells
Published online: 24 February 2017
p189 | doi:10.1038/nrendo.2017.23


Metabolism: Narciclasine boosts energy metabolism
Published online: 03 March 2017
p189 | doi:10.1038/nrendo.2017.25


Diabetes: Xeno-created pancreata — the future of diabetes treatment?
Published online: 10 February 2017
p190 | doi:10.1038/nrendo.2017.14



Stem cells: PTH regulates bone marrow progenitor fate | Genetics: Unlocking the secrets of adult human height | NAFLD: Vitamin D-induced autophagy prevents steatosis

Diabetes: A diabetes mellitus guideline gone wrong — the 2017 ACP update
Philip Home
Published online: 03 February 2017
p191 | doi:10.1038/nrendo.2017.9
An recent update on the 2012 ACP diabetes mellitus guidelines relies on a formal review, which excluded studies in which standard of care was the comparator, and thus excludes most of the key randomized controlled trials in the diabetes arena. An over-reliance on confounded observational studies is a consequence, limiting the usefulness of this update.
Full Text | PDF
Clinical guidelines: Thyroid and pregnancy — time for universal screening?
Alex Stagnaro-Green
Published online: 24 February 2017
p192 | doi:10.1038/nrendo.2017.17
The 2017 American Thyroid Association thyroid and pregnancy guidelines provide an exhaustive review of a rapidly evolving literature and comprehensive recommendations. Although agreeing with most of the recommendations, I present an alternative perspective on the normal range of TSH in pregnancy, management of women on levothyroxine preconception and universal screening for thyroid disorders during pregnancy.
Full Text | PDF
Cancer immunotherapy — immune checkpoint blockade and associated endocrinopathies
David J. Byun, Jedd D. Wolchok, Lynne M. Rosenberg & Monica Girotra
Published online: 20 January 2017
p195 | doi:10.1038/nrendo.2016.205
Targeting the immune system in tumour cells has become a central therapy for cancer treatment, but such drugs can lead to adverse effects. In this Review, the authors describe the immune-related endocrinopathies, such as hypophysitis, thyroid dysfunction and the development of diabetes mellitus that can result from cancer immunotherapy.
Abstract | Full Text | PDF
Mechanisms of diabetes mellitus-induced bone fragility
Nicola Napoli et al.
Published online: 23 September 2016
p208 | doi:10.1038/nrendo.2016.153
Diabetes mellitus is associated with an increased risk of fragility fractures. Here, Napoli and colleagues discuss the complex interactions between glucose homeostasis and bone fragility, the epidemiology of fractures in patients with diabetes mellitus and the effects of antidiabetic drugs on bone health.
Abstract | Full Text | PDF
Hormone-replacement therapy: current thinking
Roger A. Lobo
Published online: 07 October 2016
p220 | doi:10.1038/nrendo.2016.164
Clinical practice regarding the use of hormone-replacement therapy (HRT) has undergone many changes since its introduction in the 1940s. Here, Roger Lobo frames the current thinking on the use of HRT in postmenopausal women, beginning with a historical perspective and then discussing how the interpretation of HRT data has changed over time.
Abstract | Full Text | PDF
Consensus Statement on next-generation-sequencing-based diagnostic testing of hereditary phaeochromocytomas and paragangliomas
Rodrigo A. Toledo et al.
Published online: 18 November 2016
p233 | doi:10.1038/nrendo.2016.185
As a large number of genes have been implicated in the development of hereditary phaeochromocytomas and paragangliomas (PPGLs), next-generation sequencing (NGS) technology is ideally suited for carrying out genetic screening. This Consensus Statement proposes specific recommendations for the use of diagnostic NGS in hereditary PPGLs.
Abstract | Full Text | PDF | Supplementary information
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*Journal Citation Reports, Thomson, 20015. Nature Reviews Endocrinology was previously published as Nature Clinical Practice Endocrinology & Metabolism.

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