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woensdag 13 december 2017

Nature Reviews Nephrology - Table of Contents alert Volume 14 Issue 1

Nature Reviews Nephrology
 
 
TABLE OF CONTENTS
 
January 2018 Volume 14 Number 1
 
Nature Reviews Nephrology cover
2016 2-year Impact Factor 12.146 Journal Metrics 2-year Median 9
In this issue
Research Highlights
News and Views
Reviews
Correspondence
 
Also this month
 Featured article:
The neural basis of homeostatic and anticipatory thirst
Claire Gizowski and Charles W. Bourque

 
 

 
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RESEARCH HIGHLIGHTS
 
Top

Regenerative medicine: A step closer to kidneys in a dish
Published online: 20 November 2017
p1 | doi:10.1038/nrneph.2017.162

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Nephrotic syndrome: AVIL mutations reduce podocyte migration rate in SRNS
Published online: 13 November 2017
p2 | doi:10.1038/nrneph.2017.158

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Hypertension: Peripheral control of the systemic hypoxic response
Published online: 13 November 2017
p2 | doi:10.1038/nrneph.2017.160

PDF


Tubular disease: Anti-LRP2 nephropathy
Published online: 13 November 2017
p3 | doi:10.1038/nrneph.2017.159

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Gene expression: Single-cell RNA sequencing of collecting duct cells
Published online: 20 November 2017
p3 | doi:10.1038/nrneph.2017.163

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Epigenetics: EWAS of kidney function
Published online: 20 November 2017
p3 | doi:10.1038/nrneph.2017.164

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NEWS AND VIEWS
 
Top
Chronic kidney disease: Intensive blood pressure reduction lowers mortality in CKD
Stephen P. Juraschek & Lawrence J. Appel

Published online: 07 November 2017
p5 | doi:10.1038/nrneph.2017.154

Hypertension is a risk factor for chronic kidney disease (CKD), but the optimal blood pressure (BP) target in patients with stage 3-5 CKD is unclear. Now, a meta-analysis reports that more-intensive BP control is associated with a reduced risk of all-cause mortality compared with less-intensive BP goals in this high-risk population.
Full Text | PDF

 
Clinical trials: Treatment of HCV-infected patients with advanced kidney disease
Marco Ladino & David Roth

Published online: 27 November 2017
p6 | doi:10.1038/nrneph.2017.161

Antiviral treatment options for HCV-infected patients with advanced kidney disease are limited because few clinical trials have tested the efficacy of antiviral drugs in this population. Now, a phase III trial of two pan-genotypic drugs demonstrates excellent viral clearance with minimal adverse events in HCV-infected patients with advanced kidney disease.
Full Text | PDF

 
Acute kidney injury: Precision perioperative care protects the kidneys
Azra Bihorac & Charles E. Hobson

Published online: 13 December 2017
p8 | doi:10.1038/nrneph.2017.170

Standardized prevention approaches can decrease the incidence of acute kidney injury among high-risk patients. Now, the INPRESS study demonstrates that a personalized intraoperative blood pressure management strategy guided by risk stratification can improve perioperative practice and reduce the risk of organ dysfunction among high-risk patients undergoing major surgery.
Full Text | PDF

 
 
 
REVIEWS
 
Top
The neural basis of homeostatic and anticipatory thirst
Claire Gizowski & Charles W. Bourque

Published online: 13 November 2017
p11 | doi:10.1038/nrneph.2017.149

The perception of thirst is critical for the control of body fluid homeostasis. In this Review, Gizowski and Bourque discuss the importance of thirst for body fluid balance and describe the central neural networks that regulate thirst, including adaptive changes to systemic processes and feedforward anticipatory responses that precede physiological challenges to maintain body fluid balance.
Abstract | Full Text | PDF

 
The renaissance of complement therapeutics
Daniel Ricklin, Dimitrios C. Mastellos, Edimara S. Reis & John D. Lambris

Published online: 04 December 2017
p26 | doi:10.1038/nrneph.2017.156

Complement activation has important physiological and pathological implications for kidney-related and other diseases. Here, the authors discuss the state of the art of complement therapeutics, including the targets, candidate drugs, insights from clinical trials and evolving challenges for the field.
Abstract | Full Text | PDF

 
Modelling diabetic nephropathy in mice
Kengo Azushima, Susan B. Gurley & Thomas M. Coffman

Published online: 24 October 2017
p48 | doi:10.1038/nrneph.2017.142

Animal models that faithfully recapitulate human diabetic nephropathy (DN) are needed to study disease pathogenesis, identify drug targets and test new therapies. Here, the authors review progress in developing mouse models of DN, the limitations of current models, and opportunities for future development.
Abstract | Full Text | PDF

 
Dyslipidaemia in nephrotic syndrome: mechanisms and treatment
Shipra Agrawal, Joshua J. Zaritsky, Alessia Fornoni & William E. Smoyer

Published online: 27 November 2017
p57 | doi:10.1038/nrneph.2017.155

Dyslipidaemia is a common consequence of nephrotic syndrome, and results in various cardiovascular and metabolic complications. In this Review, the authors discuss the mechanisms that underlie the development of dyslipidaemia, and the treatment options that are available to ameliorate its effects.
Abstract | Full Text | PDF

 
 
CORRESPONDENCE
 
Top
Clarifying the relationship between metformin, acute kidney injury and lactic acidosis
Samira Bell, Enrique Soto-Pedre, Paul Connelly, Shona Livingstone & Ewan Pearson

Published online: 13 December 2017
p70 | doi:10.1038/nrneph.2017.172

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REPLY
 
Top
Further clarifying the relationship between metformin, acute kidney injury and lactic acidosis
Connie M. Rhee & Kamyar Kalantar-Zadeh

Published online: 13 December 2017
p70 | doi:10.1038/nrneph.2017.174

Full Text | PDF
 
Corrigendum: Dyslipidaemia in nephrotic syndrome: mechanisms and treatment
Shipra Agrawal, Joshua J. Zaritsky, Alessia Fornoni & William E. Smoyer

Published online: 13 December 2017
p70 | doi:10.1038/nrneph.2017.175

Full Text | PDF
 
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