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donderdag 2 november 2017

The EMBO Journal Table of Contents for 02 November 2017; Vol. 36, No. 21

http://embopress.org/collections
02 November 2017 | Volume 36, Number 21 Submit


Table of Contents

News & Views
Articles
COVER

Volume 36, Number 21



News & Views
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Two new studies establish conditions for culturing ESC‐derived germ cells, enabling global DNA demethylation and subsequent female sex determination.

Mark E Gill and Antoine HFM Peters
Published online 04.10.2017

Articles
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In vitro reconstitution of female sex determination using ESC‐derived germ cells demonstrates requirement of integrated signaling and epigenetic background for fetal oocyte induction.

Hidetaka Miyauchi, Hiroshi Ohta, So Nagaoka, Fumio Nakaki, Kotaro Sasaki, Katsuhiko Hayashi, Yukihiro Yabuta, Tomonori Nakamura, Takuya Yamamoto and Mitinori Saitou
Published online 19.09.2017

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Aggregation of hyper‐phosphorylated Tau in the somatodendritic domain, as often seen in Alzheimer's disease, is caused by local translation triggered by the presence of amyloid‐β.

Chuanzhou Li and Jürgen Götz
Published online 01.09.2017

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MLL‐ENL mediated transformation of hematopoietic stem/progenitors can occur independent from beta‐catenin in leukemia mouse models.

Teerapong Siriboonpiputtana, Bernd B Zeisig, Magdalena Zarowiecki, Tsz Kan Fung, Maria Mallardo, Chiou‐Tsun Tsai, Priscilla Nga Ieng Lau, Quoc Chinh Hoang, Pedro Veiga, Jo Barnes, Claire Lynn, Amanda Wilson, Boris Lenhard and Chi Wai Eric So
Published online 04.10.2017

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Cholesterol transporter OSBP uses a large amount of phosphatidylinositol 4‐phosphate to control cholesterol distribution and consequently the gradient of membrane lipid order along the secretory pathway.

Bruno Mesmin, Joëlle Bigay, Joël Polidori, Denisa Jamecna, Sandra Lacas‐Gervais and Bruno Antonny
Published online 04.10.2017

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A SIRT1‐Myc axis affects mouse embryogenesis and epigenetic regulation of mESC function by regulating expression of methionine adenosyltransferase 2.

Shuang Tang, Yi Fang, Gang Huang, Xiaojiang Xu, Elizabeth Padilla‐Banks, Wei Fan, Qing Xu, Sydney M Sanderson, Julie F Foley, Scotty Dowdy, Michael W McBurney, David C Fargo, Carmen J Williams, Jason W Locasale, Ziqiang Guan and Xiaoling Li
Published online 11.10.2017

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PIWI proteins like Aubergine protect the germline from aberrant transposon activation but also facilitate self‐renewal and differentiation of germline stem cells in flies by repressing specific mRNAs.

Patricia Rojas‐Ríos, Aymeric Chartier, Stéphanie Pierson and Martine Simonelig
Published online 13.10.2017 Open Access

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Regulation of actin dynamics affects DNA synthesis in human cells and Xenopus egg extracts through multiple mechanisms, including nuclear transport and chromatin loading of replication factors.

Nikolaos Parisis, Liliana Krasinska, Bethany Harker, Serge Urbach, Michel Rossignol, Alain Camasses, James Dewar, Nathalie Morin and Daniel Fisher
Published online 05.10.2017

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The methyl‐lysine reader L3MBTL3 switches the Notch coactivator RBPJ to a transcriptional repressor by mediating removal of activating histone marks at Notch target genes.

Tao Xu, Sung‐Soo Park, Benedetto Daniele Giaimo, Daniel Hall, Francesca Ferrante, Diana M Ho, Kazuya Hori, Lucas Anhezini, Iris Ertl, Marek Bartkuhn, Honglai Zhang, Eléna Milon, Kimberly Ha, Kevin P Conlon, Rork Kuick, Brandon Govindarajoo, Yang Zhang, Yuqing Sun, Yali Dou, Venkatesha Basrur, Kojo SJ Elenitoba‐Johnson, Alexey I Nesvizhskii, Julian Ceron, Cheng‐Yu Lee, Tilman Borggrefe, Rhett A Kovall and Jean‐François Rual
Published online 13.10.2017 Open Access

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PKA1 inhibits PKG activity to prevent premature parasite exit from the host cell due to intracellular acidification.

Yonggen Jia, Jean‐Baptiste Marq, Hugo Bisio, Damien Jacot, Christina Mueller, Lu Yu, Jyoti Choudhary, Mathieu Brochet and Dominique Soldati‐Favre
Published online 13.10.2017

 
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