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woensdag 6 september 2017

Leukemia - Table of Contents alert Volume 31 Issue 9

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Leukemia
TABLE OF CONTENTS

Volume 31, Issue 9 (September 2017)

In this issue
Perspective
Reviews
Concise Review
Original Articles
Letters to the Editor
Correspondence

Also new
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Perspective

Top

New drugs in myeloma: beware of phase I trial results, beware of cost and demand for new trials

P Moreau

Leukemia 2017 31: 1843-1844; advance online publication, June 30, 2017; 10.1038/leu.2017.188

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Reviews

Top

Assessing the thrombotic risk of patients with essential thrombocythemia in the genomic era

L Falchi, H M Kantarjian and S Verstovsek

Leukemia 2017 31: 1845-1854; advance online publication, May 22, 2017; 10.1038/leu.2017.150

Abstract | Full Text

Gemtuzumab ozogamicin in acute myeloid leukemia

C D Godwin, R P Gale and R B Walter

Leukemia 2017 31: 1855-1868; advance online publication, June 13, 2017; 10.1038/leu.2017.187

Abstract | Full Text

Concise Review

Top

CHIP, ICUS, CCUS and other four-letter words

R Bejar

Leukemia 2017 31: 1869-1871; advance online publication, June 8, 2017; 10.1038/leu.2017.181

Abstract | Full Text

Original Articles

Top

CHRONIC LYMPHOCYTIC LEUKEMIA

Duvelisib treatment is associated with altered expression of apoptotic regulators that helps in sensitization of chronic lymphocytic leukemia cells to venetoclax (ABT-199)

V M Patel, K Balakrishnan, M Douglas, T Tibbitts, E Y Xu, J L Kutok, M Ayers, A Sarkar, R Guerrieri, W G Wierda, S O'Brien, N Jain, H M Stern and V Gandhi

Leukemia 2017 31: 1872-1881; advance online publication, December 26, 2016; 10.1038/leu.2016.382

Abstract | Full Text

Mutations in NOTCH1 PEST domain orchestrate CCL19-driven homing of chronic lymphocytic leukemia cells by modulating the tumor suppressor gene DUSP22

F Arruga, B Gizdic, C Bologna, S Cignetto, R Buonincontri, S Serra, T Vaisitti, K Gizzi, N Vitale, G Garaffo, E Mereu, F Diop, F Neri, D Incarnato, M Coscia, J Allan, R Piva, S Oliviero, R R Furman, D Rossi, G Gaidano and S Deaglio

Leukemia 2017 31: 1882-1893; advance online publication, December 26, 2016; 10.1038/leu.2016.383

Abstract | Full Text

Effects of miRNA-15 and miRNA-16 expression replacement in chronic lymphocytic leukemia: implication for therapy

G Cutrona, S Matis, M Colombo, C Massucco, G Baio, F Valdora, L Emionite, S Fabris, A G Recchia, M Gentile, C E Neumaier, D Reverberi, R Massara, S Boccardo, L Basso, S Salvi, F Rosa, M Cilli, S Zupo, M Truini, P Tassone, M Calabrese, M Negrini, A Neri, F Morabito, F Fais and M Ferrarini

Leukemia 2017 31: 1894-1904; advance online publication, January 5, 2017; 10.1038/leu.2016.394

Abstract | Full Text

PPAR-delta promotes survival of chronic lymphocytic leukemia cells in energetically unfavorable conditions

Y-J Li, L Sun, Y Shi, G Wang, X Wang, S E Dunn, C Iorio, R A Screaton and D E Spaner

Leukemia 2017 31: 1905-1914; advance online publication, January 4, 2017; 10.1038/leu.2016.395

Abstract | Full Text

Trends in overall survival and costs of multiple myeloma, 2000–2014 OPEN

R Fonseca, S Abouzaid, M Bonafede, Q Cai, K Parikh, L Cosler and P Richardson

Leukemia 2017 31: 1915-1921; advance online publication, December 23, 2016; 10.1038/leu.2016.380

Abstract | Full Text

Bortezomib and thalidomide maintenance after stem cell transplantation for multiple myeloma: a PETHEMA/GEM trial

L Rosiñol, A Oriol, A I Teruel, A L de la Guía, MaJ Blanchard, J de la Rubia, M Granell, MaA Sampol, L Palomera, Y González, MaA Etxebeste, R Martínez-Martínez, M T Hernández, F de Arriba, A Alegre, MaT Cibeira, MaV Mateos, J Martínez-López, J J Lahuerta, J San Miguel and J Bladé on behalf of the Programa Español de Tratamientos en Hematología/Grupo Español de Mieloma (PETHEMA/GEM)

Leukemia 2017 31: 1922-1927; advance online publication, January 23, 2017; 10.1038/leu.2017.35

Abstract | Full Text

MYELODYSPLASTIC SYNDROME

The clonal origins of leukemic progression of myelodysplasia

T Kim, M S Tyndel, H J Kim, J-S Ahn, S H Choi, H J Park, Y-k Kim, D-H Yang, J-J Lee, S-H Jung, S Y Kim, Y H Min, J-W Cheong, S K Sohn, J H Moon, M Choi, M Lee, Z Zhang and D(D H) Kim

Leukemia 2017 31: 1928-1935; advance online publication, January 16, 2017; 10.1038/leu.2017.17

Abstract | Full Text

Molecular characterization of EZH2 mutant patients with myelodysplastic/myeloproliferative neoplasms

J Rinke, J P Müller, M F Blaess, A Chase, M Meggendorfer, V Schäfer, N Winkelmann, C Haferlach, N C P Cross, A Hochhaus and T Ernst

Leukemia 2017 31: 1936-1943; advance online publication, June 19, 2017; 10.1038/leu.2017.190

Abstract | Full Text

A phase 3 randomized placebo-controlled trial of darbepoetin alfa in patients with anemia and lower-risk myelodysplastic syndromes OPEN

U Platzbecker, A Symeonidis, E N Oliva, J S Goede, M Delforge, J Mayer, B Slama, S Badre, E Gasal, B Mehta and J Franklin

Leukemia 2017 31: 1944-1950; advance online publication, June 19, 2017; 10.1038/leu.2017.192

Abstract | Full Text

CHRONIC MYELOPROLIFERATIVE NEOPLASMS

Novel BET protein proteolysis-targeting chimera exerts superior lethal activity than bromodomain inhibitor (BETi) against post-myeloproliferative neoplasm secondary (s) AML cells

D T Saenz, W Fiskus, Y Qian, T Manshouri, K Rajapakshe, K Raina, K G Coleman, A P Crew, A Shen, C P Mill, B Sun, P Qiu, T M Kadia, N Pemmaraju, C DiNardo, M-S Kim, A J Nowak, C Coarfa, C M Crews, S Verstovsek and K N Bhalla

Leukemia 2017 31: 1951-1961; advance online publication, February 2, 2017; 10.1038/leu.2016.393

Abstract | Full Text

TRANSCRIPTIONAL CONTROL AND SIGNAL TRANSDUCTION, CELL CYCLE

Mass cytometry analysis reveals hyperactive NF Kappa B signaling in myelofibrosis and secondary acute myeloid leukemia

D A C Fisher, O Malkova, E K Engle, C A Miner, M C Fulbright, G K Behbehani, T B Collins, S Bandyopadhyay, A Zhou, G P Nolan and S T Oh

Leukemia 2017 31: 1962-1974; advance online publication, December 23, 2016; 10.1038/leu.2016.377

Abstract | Full Text

PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias

C Ronchini, A Brozzi, L Riva, L Luzi, A M Gruszka, G E M Melloni, E Scanziani, G Dharmalingam, M Mutarelli, V Belcastro, S Lavorgna, V Rossi, O Spinelli, A Biondi, A Rambaldi, F Lo-Coco, D di Bernardo and P G Pelicci

Leukemia 2017 31: 1975-1986; advance online publication, December 27, 2016; 10.1038/leu.2016.386

Abstract | Full Text

Letters to the Editor

Top

Spotlight on pomalidomide: could less be more? OPEN

T Zander, S Aebi, T Pabst, C Renner and C Driessen

Leukemia 2017 31: 1987-1989; advance online publication, May 22, 2017; 10.1038/leu.2017.156

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Novel PDGFRB fusions in childhood B- and T-acute lymphoblastic leukemia

A M Heilmann, A B Schrock, J He, M Nahas, K Curran, N Shukla, S Cramer, L Draper, A Verma, R Erlich, J Ross, P Stephens, V A Miller, S M Ali, J-A Verglio, M S Tallman and T I Mughal

Leukemia 2017 31: 1989-1992; advance online publication, May 29, 2017; 10.1038/leu.2017.161

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Identification of a novel PML-RARG fusion in acute promyelocytic leukemia

J-S Ha, Y R Do, C-S Ki, C Lee, D-H Kim, W Lee, N-H Ryoo and D-S Jeon

Leukemia 2017 31: 1992-1995; advance online publication, May 30, 2017; 10.1038/leu.2017.167

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MDS with deletions in the long arm of chromosome 11 are associated with a high frequency of SF3B1 mutations

A Stengel, W Kern, M Meggendorfer, T Haferlach and C Haferlach

Leukemia 2017 31: 1995-1997; advance online publication, June 8, 2017; 10.1038/leu.2017.180

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Trends in pre- and post-transplant therapies with first autologous hematopoietic cell transplantation among patients with multiple myeloma in the United States, 2004–2014

A D'Souza, M-J Zhang, J Huang, M Fei, M Pasquini, M Hamadani and P Hari

Leukemia 2017 31: 1998-2000; advance online publication, June 13, 2017; 10.1038/leu.2017.185

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The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia OPEN

A Rio-Machin, G Gómez-López, J Muñoz, F Garcia-Martinez, A Maiques-Diaz, S Alvarez, R N Salgado, M Shrestha, R Torres-Ruiz, C Haferlach, M J Larráyoz, M J Calasanz, J Fitzgibbon and J C Cigudosa

Leukemia 2017 31: 2000-2005; advance online publication, June 20, 2017; 10.1038/leu.2017.194

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Recurrent cyclin D2 mutations in myeloid neoplasms

V Khanna, C A Eide, C E Tognon, J E Maxson, B Wilmot, D Bottomly, S McWeeney, D K Edwards V, B J Druker and J W Tyner

Leukemia 2017 31: 2005-2008; advance online publication, June 20, 2017; 10.1038/leu.2017.195

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Correspondence

Top

Do we need to distinguish exosomes from microvesicles in hematological malignancies?

A Caivano, L Del Vecchio and P Musto

Leukemia 2017 31: 2009-2010; advance online publication, June 28, 2017; 10.1038/leu.2017.205

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