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woensdag 19 juli 2017

Nature Reviews Neuroscience contents August 2017 Volume 18 Number 8 pp 451-509

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Nature Reviews Neuroscience


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TABLE OF CONTENTS
 
August 2017 Volume 18 Number 8
Nature Reviews Neuroscience cover
2016 2-year Impact Factor 28.880 Journal Metrics 2-year Median 23
In this issue
Research Highlights
Progress
Reviews

Also this month
 Featured article:
Mammalian empathy: behavioural manifestations and neural basis
Frans B. M. de Waal & Stephanie D. Preston


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RESEARCH HIGHLIGHTS
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Neural circuits: The influence of hunger
p451 | doi:10.1038/nrn.2017.93
In mice, hypothalamic agouti-related peptide-expressing neurons modulate food-cue-associated insular cortex activity to influence behaviour.

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Neuroimmunology: Mistaken identity
p452 | doi:10.1038/nrn.2017.87
Fragments of the protein α-synuclein, which accumulates in substantia nigra neurons in Parkinson disease, are expressed on the surface of these substantia nigra neurons and induce a form of autoimmunity that could account for the degeneration of these cells in the disease.

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Gut-brain communication: Making contact
p452 | doi:10.1038/nrn.2017.89
Enterochromaffin cells in the gut epithelium act as chemosensors and can modulate neural function in response to intestinal signals.

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Psychiatric disorders: A sensitive window
p453 | doi:10.1038/nrn.2017.84
In mice, postnatal stress leads to long-lasting changes in transcription in the ventral tegmental area, sensitizing the brain to stress later in life.

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Sensory systems: Tasting the water
p454 | doi:10.1038/nrn.2017.82
Water in the external environment is detected by acid-sensing taste receptor cells via a carbonic anhydrase 4-mediated pH change.

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Microglia: A protective population?
p454 | doi:10.1038/nrn.2017.83
Disease progression in a mouse model of Alzheimer disease is associated with the appearance of a population of disease-associated microglia that can phagocytose amyloid-β.

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Neural coding: Face values
p456 | doi:10.1038/nrn.2017.81
Neurons in the 'face patch' system in macaques code features of realistic faces along various continuous axes.

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Pain: A painful loss of inhibition
p456 | doi:10.1038/nrn.2017.88
The development of chronic neuropathic pain is associated with cortical hyperexcitability and a marked decrease in inhibition, particularly from cortical somatostatin-expressing interneurons.

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Cancer: Appetite suppressors
p457 | doi:10.1038/nrn.2017.86
Calcitonin gene-related peptide-expressing neurons in the external parabrachial nucleus can drive cancer-induced anorexia in mice.

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IN BRIEF

Neural circuits: Hanging in the balance | Learning and memory: Catching fear memories | Neural development: Regional influence | Neurodegenerative disorders: Amyloid clearance
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Nature Reviews Neuroscience
JOBS of the week
Postdoctoral Research Fellow in Systems Neuroscience
University of Sussex
Research Fellow: Neuroscience of Pain, Analgesics, AAV Gene Therapy Job
Mayo Clinic
Assistant Professor, Behavioral Neuroscience
Western Washington University
Postdoctoral position in Neuroscience: neural networks underlying behavior
Max Planck Society, caesar
Post-doctoral Fellow / Staff Scientist in Developmental Neuroscience
Children's National Health Systems
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PROGRESS
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Neural circuits underlying thirst and fluid homeostasis
Christopher A. Zimmerman, David E. Leib & Zachary A. Knight
p459 | doi:10.1038/nrn.2017.71
Thirst is a homeostatic response to changes in fluid balance and is governed by a set of interconnected brain structures known as the lamina terminalis. In this Progress article, Knight and colleagues summarize recent updates to our understanding of the neural circuitry underlying thirst and drinking behaviour in mammals.

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REVIEWS
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Neuroimmunology and neuroepigenetics in the establishment of sex differences in the brain
Margaret M. McCarthy, Bridget M. Nugent & Kathryn M. Lenz
p471 | doi:10.1038/nrn.2017.61
Sex differences in behaviour and disease vulnerability are mirrored by the cellular and molecular sexual dimorphism of the brain. McCarthy and colleagues review findings that have highlighted the roles of inflammation and epigenetics in sex-specific brain differentiation and function.
Abstract | Full Text | PDF

Taste buds: cells, signals and synapses
Stephen D. Roper & Nirupa Chaudhari
p485 | doi:10.1038/nrn.2017.68
Mammals detect the nutrient content, palatability and potential toxicity of food through taste buds that are present mainly in the tongue. In this Review, Roper and Chaudhari discuss the taste bud cells, receptors and transmitters that are involved in taste detection, how these cells communicate with sensory afferent fibres, and peripheral taste coding.
Abstract | Full Text | PDF

Mammalian empathy: behavioural manifestations and neural basis
Frans B. M. de Waal & Stephanie D. Preston
p498 | doi:10.1038/nrn.2017.72
Empathy is a characteristic of all mammals that ranges from being sensitive to another's emotions to adopting their perspective. In this Review, de Waal and Preston discuss current hypotheses concerning how the emotional states of others are understood in a variety of species.
Abstract | Full Text | PDF

Erratum: Non-motor features of Parkinson disease
Anthony H. V. Schapira, K. Ray Chaudhuri & Peter Jenner
p509 | doi:10.1038/nrn.2017.91
Full Text | PDF
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