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vrijdag 30 juni 2017

The Lancet: [Articles] Foley catheterisation versus oral misoprostol for induction of labour in hypertensive women in...

[Articles] Foley catheterisation versus oral misoprostol for induction of labour in hypertensive women in India (INFORM): a multicentre, open-label, randomised controlled trial
Oral misoprostol was more effective than transcervical Foley catheterisation for induction of labour in women with pre-eclampsia or hypertension. Future studies are required to assess whether oxytocin augmentation following misoprostol can be replaced by regular doses of oral misoprostol tablets.
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[Comment] Oral misoprostol for induction of labour in hypertensive pregnancies
Oral misoprostol is simple to use and is thus an attractive and easy option in low-resource settings where the doctor–patient ratio is suboptimum and close monitoring of intravenous drug dosage is often not possible.1 Results of the PROBAAT-II study2 in women with a wide range of indications for induction of labour at term showed oral misoprostol treatment to be non-inferior to Foley catheterisation. Now, the findings of Shuchita Mundle and colleagues' INFORM study3 in The Lancet advance the role of oral misoprostol for induction of labour.
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[Clinical Picture] Generalised cowpox virus infection
A 24-year-old man presented to our dermatology clinic with three haemorrhagic partially ulcerated nodules located in the right groin, surrounded by inflammation and oedema, which had evolved over the course of 1 week (figure), and fatigue. He had identical isolated skin lesions on the right shoulder, left knee, and left ankle. On examination he was febrile (temperature 38·5°C) and had tender generalised lymphadenopathy. He had no signs or personal history of atopy (atopic dermatitis, hay fever, asthma), although family history was positive for a sister with dermatitis.
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[Viewpoint] Saving lives efficiently across sectors: the need for a Congressional cost-effectiveness committee
In the preamble of the United States Constitution, a primary goal of government was established: "to promote the general Welfare". Upon the opening of budget deliberations for the 115th US Congressional session, we suggest an evidence-based approach for the new Congress in aligning the budget process more closely with this national goal. In particular, we underscore the efficiency of the US public health sector in promoting societal welfare, and reveal a relative underinvestment in public health compared with other sectors.
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[World Report] US Senate unveils ACA repeal bill
June 22, the Better Care Reconciliation Act, a bill designed to replace the Affordable Care Act, was revealed, among bipartisan concern and criticism. Aaron van Dorn and Rebecca Cooney report.
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