We bring you the latest news from the healthcare about the health care in the United Kingdom. Do your have news for us? Contact the editor. Watch also this special movie.

woensdag 15 maart 2017

Nature Reviews Genetics Contents April 2017 Volume 18 Number 4 pp209-267

If you are unable to see the message below, click here to view.
Nature Reviews Genetics

 
TABLE OF CONTENTS
 
April 2017 Volume 18 Number 4Advertisement

Nature Reviews Genetics cover
2015 2–year Impact Factor 35.898 Journal Metrics 2–year Median 32
In this issue
Research Highlights
Reviews
Perspectives


Also this month
Article series:
Study designs
Single-cell omics
Translational genetics
 Featured article:
Evolving health care through personal genomics
Heidi L. Rehm


 
A new open access journal dedicated to publishing the most important scientific advances in all aspects of genomics and its application in the practice of medicine. Part of the Nature Partner Journals series, the journal is published in partnership with the Center of Excellence in Genomic Medicine Research.
 
Open for submissions >>


Subscribe
 
Facebook
 
RSS
 
Recommend to library
 
Twitter
 
Advertisement
The 2017 Symposium on Translational Epigenetics will explore this rapidly growing area of investigation in biomedicine which may be key to developing novel therapies for some of the most important and intractable diseases. The symposium features talks from outstanding, international speakers in the field of translational epigenetics. Registration is free but places are limited.
www.imb.de/2017transepi
 
Advertisement
NYU Nature Conference on Neurogenetics 

August 9-11, 2017| New York, NY

Presented by: New York University (NYU) | Nature Genetics | Nature Neuroscience 

Register now!
 
RESEARCH HIGHLIGHTS

Top

Epigenetics: Rich pore methods for DNA methylation detection
p209 | doi:10.1038/nrg.2017.18
PDF


Genetic variation: HSP90 shapes human genetic variation
p210 | doi:10.1038/nrg.2017.16
PDF


Complex traits: Selecting against schooling
p210 | doi:10.1038/nrg.2017.9
PDF


Technique: Barcoding the nucleus
p211 | doi:10.1038/nrg.2017.11
PDF


Cancer genomics: ECdetect hunts extrachromosomal DNA
p212 | doi:10.1038/nrg.2017.13
PDF


Non-coding RNA: Exosomal microRNAs as novel adipokines
p212 | doi:10.1038/nrg.2017.14
PDF


Genetics
JOBS of the week
Assistant & Associate Investigator / Professors: Cancer Genetics, Epigenetics and Biomarkers
BAYLOR SCOTT & WHITE HEALTH
Faculty Position – Department of Genetics and Genome Sciences
Case Western Reserve University, School of Medicine
2 PhD Student positions in Cancer Genetics / Biology
Klinikum rechts der Isar der Technischen Universit√§t M√ľnchen - II. Medizinische Klinik
Postdoctoral Fellowship in Sleep, Chronobiology, Aging, Cognition and Genetics at GIGA-Cyclotron Research Center / In Vivo Imaging
GIGA
Postdoctoral Position in Developmental Genetics : Institut Curie, Paris, France
ERC advanced grant
More Science jobs from
Genetics
EVENT
Avian Genetics and Immunity
19.06.17
Surrey, UK
More science events from
Advertisement
nature.com webcasts

Springer Nature presents a custom webcast on: Advances in neuroscience research utilizing modern in situ RNA gene expression techniques.

Date: 23rd March 2017
Time: 10AM PDT | 1PM EDT | 5PM GMT | 6PM CET
 
Register for FREE and discover how Dr. Jerold Chun has used RNAscope to investigate the human brain.

Sponsor:
Advanced Cell Diagnostics

 
REVIEWS

Top
Article series: Study designs
The evolution of tumour phylogenetics: principles and practice
Russell Schwartz & Alejandro A. Schäffer
p213 | doi:10.1038/nrg.2016.170
The use of phylogenetics in cancer genomics is increasing owing to a growing appreciation of the importance of evolutionary theory to cancer progression. The authors provide guidance on the design and analysis of tumour phylogeny studies by surveying the range of phylogenetic methods and tools available to the cancer researcher and discussing their key applications and the unsolved problems in the field.
Abstract | Full Text | PDF | Supplementary information


Article series: Single-cell omics
Building a lineage from single cells: genetic techniques for cell lineage tracking
Mollie B. Woodworth, Kelly M. Girskis & Christopher A. Walsh
p230 | doi:10.1038/nrg.2016.159
Lineage analyses of multicellular organisms provide key insights into developmental mechanisms and how these developmental trajectories go awry in diverse diseases. This Review discusses the features, technical challenges and latest opportunities of an evolving range of sophisticated genetic techniques for tracking cell lineages in organisms. These strategies include methods for prospective tracking using engineered genetic constructs, as well as retrospective tracking based on naturally occurring somatic mutations.
Abstract | Full Text | PDF


Limb development: a paradigm of gene regulation
Florence Petit, Karen E. Sears & Nadav Ahituv
p245 | doi:10.1038/nrg.2016.167
Here, the authors review the complex gene regulatory mechanisms that underlie limb development and that determine forelimb versus hindlimb identity. They explain how the modification of these regulatory elements leads to morphological evolution, acquired regeneration capacity or limb malformations in diverse species, including humans.
Abstract | Full Text | PDF


Advertisement
nature.com webcasts

Join us for our upcoming webcast followed by live Q&A:
NEW INNOVATIONS IN DRUG DELIVERY TECHNOLOGY 

Presented by BioPharma Dealmakers

Date: Wednesday, March 29, 2017
Time: 8AM PDT | 11AM EDT | 4PM BST | 5PM CEST

REGISTER FOR FREE

Sponsored by: Corium International | Portal Instruments Inc. | TissueGen Inc. | TrioxNano
 

 
PERSPECTIVES

Top
ESSAY
Article series: Translational genetics
Evolving health care through personal genomics
Heidi L. Rehm
p259 | doi:10.1038/nrg.2016.162
The advent of genomic technologies is changing health care systems, with genomic data increasingly being applied to guide individual patient care. In this Essay, Rehm discusses how genomics is becoming an essential part of clinical care and the existing challenges that must be surmounted to take full advantage of personal genomic information.
Abstract | Full Text | PDF


Advertisement
An online-only, open access, multidisciplinary journal dedicated to publishing high-quality original research articles, reviews, editorials, commentaries, and hypothesis generating observations on all areas of breast cancer research. Part of the Nature Partner Journals series, published in partnership with the Breast Cancer Research Foundation.

Now open for submissions >>
 
nature events
Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here.

Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com
More Nature Events

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/myaccount
(You will need to log in to be recognised as a nature.com registrant).

For further technical assistance, please contact our registration department

For print subscription enquiries, please contact our subscription department

For other enquiries, please contact our feedback department

Nature Publishing Group | One New York Plaza, Suite 4500 | New York | NY 10004-1562 | USA

Nature Publishing Group's worldwide offices:
London - Paris - Munich - New Delhi - Tokyo - Melbourne
San Diego - San Francisco - Washington - New York - Boston

Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at The Campus, 4 Crinan Street, London, N1 9XW.

© 2017 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.

nature publishing group