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donderdag 9 februari 2017

The Lancet: [Department of Error] Department of Error

[Department of Error] Department of Error
Stringhini S, Carmeli C, Jokela M, et al. Socioeconomic status and the 25 × 25 risk factors as determinants of premature mortality: a multicohort study and meta-analysis of 1·7 million men and women. Lancet 2017; published online Jan 31. http://dx.doi.org/10.1016/S0140-6736(16)323807—In the supplementary appendix for this Article, some forest plots were omitted for all-cause mortality that have now been added. This correction has been made to the online version as of Feb 7, 2017.
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[Comment] The academic case for repealing Trump's refugee and travel ban
Academics provide education and undertake research to improve understanding, and hopefully make the world a better place. US President Donald Trump's recent executive order on Jan 27, 2017,1 banning travel to the USA from seven predominantly Muslim countries (Iran, Iraq, Libya, Somalia, Sudan, Syria, and Yemen) for 90 days, suspending the US resettlement programme for all refugees for 120 days, indefinitely suspending the entry of Syrian refugees, and reducing the number of resettled refugees from 110 000 to 50 000, has dramatically and negatively affected millions of people's lives.
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[Comment] A quarter-dose quadpill for initial treatment of hypertension
The immediate goal of antihypertensive therapy is the prompt achievement of target blood pressure without adverse effects on quality of life. The efficacy, tolerability, and safety of available pharmacological agents makes attainment of these goals possible in most patients. Nevertheless, undertreatment of hypertension results in the continued occurrence of many preventable and potentially negative outcomes for patients worldwide. In the National Health and Nutrition Examination Survey (NHANES) reported in 2008,1 estimates of age-standardised cardiovascular mortality directly attributable to uncontrolled blood pressure in the USA were 260 cases per 100 000 women and 290 cases per 100 000 men.
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[Seminar] Type 2 diabetes
415 million people live with diabetes worldwide, and an estimated 193 million people have undiagnosed diabetes. Type 2 diabetes accounts for more than 90% of patients with diabetes and leads to microvascular and macrovascular complications that cause profound psychological and physical distress to both patients and carers and put a huge burden on health-care systems. Despite increasing knowledge regarding risk factors for type 2 diabetes and evidence for successful prevention programmes, the incidence and prevalence of the disease continues to rise globally.
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[Seminar] Dilated cardiomyopathy
Dilated cardiomyopathy is defined by the presence of left ventricular dilatation and contractile dysfunction. Genetic mutations involving genes that encode cytoskeletal, sarcomere, and nuclear envelope proteins, among others, account for up to 35% of cases. Acquired causes include myocarditis and exposure to alcohol, drugs and toxins, and metabolic and endocrine disturbances. The most common presenting symptoms relate to congestive heart failure, but can also include circulatory collapse, arrhythmias, and thromboembolic events.
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