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woensdag 22 februari 2017

Nature Reviews Rheumatology - Table of Contents alert Volume 13 Issue 3

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Nature Reviews Rheumatology


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TABLE OF CONTENTS
 
March 2017 Volume 13 Number 3
Nature Reviews Rheumatology cover
2015 2-year Impact Factor 10.531 Journal Metrics 2-year Median 7
In this issue
Research Highlights
News and Views
Reviews
Perspectives

Also this month
 Featured article:
Paediatric rheumatic diseases: Navigating the transition from paediatric to adult care
Erica F. Lawson & Elizabeth D. Mellins


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RESEARCH HIGHLIGHTS
Top

Vasculitis syndromes: Loss of immunoinhibitory checkpoint implicated in GCA
Published online: 09 February 2017
p129 | doi:10.1038/nrrheum.2017.20

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Osteoarthritis: UCMA links cartilage and bone in OA
Published online: 09 February 2017
p130 | doi:10.1038/nrrheum.2017.9

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Systemic lupus erythematosus: New pathway blocks disease in lupus-prone mice
Published online: 19 January 2017
p131 | doi:10.1038/nrrheum.2017.2

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Inflammatory myopathies: Genetic associations with IBM
Published online: 09 February 2017
p131 | doi:10.1038/nrrheum.2017.8

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Rheumatoid arthritis: Defective IL-10-producing Breg cells
Published online: 02 February 2017
p132 | doi:10.1038/nrrheum.2017.10

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Rheumatoid arthritis: Nicotine exacerbates arthritis
Published online: 19 January 2017
p132 | doi:10.1038/nrrheum.2017.3

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IN BRIEF

Bone: miR-106b promotes osteoporosis in mice | Therapy: Retreatment with rituximab is beneficial in RA | Rheumatoid arthritis: S100A9 does not predict response to etanercept | Undifferentiated arthritis: Features of UA that develops into RA revealed
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Nature Reviews Rheumatology
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NEWS AND VIEWS
Top
Rheumatoid arthritis: TAK-ing the road to suppress inflammation in synovial fibroblasts
Mojca Frank-Bertoncelj & Steffen Gay
Published online: 12 January 2017
p133 | doi:10.1038/nrrheum.2016.220
Positioned at the crossroads of TNF, IL-1 and Toll-like receptor signalling cascades and cytokine-driven chromatin remodelling, TAK1 is emerging as a new therapeutic target in rheumatoid arthritis.
Full Text | PDF

Connective tissue disease: Reflections on the EULAR recommendations for the treatment of systemic sclerosis
Janet E. Pope
Published online: 05 January 2017
p134 | doi:10.1038/nrrheum.2016.212
The treatment of systemic sclerosis (SSc) is complex as multiple organs are frequently involved and treatment is either for overall disease modification or is organ specific. EULAR has updated its treatment recommendations for SSc, reflecting data from some new trials. However, some features of SSc are not included.
Full Text | PDF | Supplementary information

Therapy: Cardiovascular safety of celecoxib, naproxen and ibuprofen
Michael T. Nurmohamed
Published online: 27 January 2017
p136 | doi:10.1038/nrrheum.2017.4
The PRECISION trial demonstrates that celecoxib is noninferior to ibuprofen and naproxen in regard to cardiovascular safety. Do these findings mark the end of the debate on this issue, or do aspects of the trial mean the implications for clinical practice are not clear-cut?
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Paediatric rheumatic diseases: Navigating the transition from paediatric to adult care
Erica F. Lawson & Elizabeth D. Mellins
Published online: 09 February 2017
p138 | doi:10.1038/nrrheum.2017.16
New guidelines from EULAR and the Paediatric Rheumatology European Society recommend a set of quality standards for the care of young adults with childhood-onset rheumatic diseases during their transfer from paediatric to adult rheumatology care providers. Can the application of these guidelines prevent patients from getting lost in the system?
Full Text | PDF

 
REVIEWS
Top
Ectopic lymphoid neogenesis in rheumatic autoimmune diseases
Michele Bombardieri, Myles Lewis & Costantino Pitzalis
Published online: 09 February 2017
p141 | doi:10.1038/nrrheum.2016.217
Ectopic lymphoid structures have been identified in the target organs of a subset of patients with rheumatic autoimmune diseases. This Review describes these structures and summarizes our current understanding of how they form, function and contribute to autoimmunity.
Abstract | Full Text | PDF

The changing role of TGFβ in healthy, ageing and osteoarthritic joints
Peter M. van der Kraan
Published online: 02 February 2017
p155 | doi:10.1038/nrrheum.2016.219
Transforming growth factor-β (TGFβ) is a pleiotropic cytokine that is important in the regulation of joint homeostasis and disease. In this Review, the changing role of TGFβ in normal joint homeostasis, ageing and osteoarthritis is discussed.
Abstract | Full Text | PDF

Innate lymphoid cells in autoimmunity: emerging regulators in rheumatic diseases
Medya M. Shikhagaie, Kristine Germar, Suzanne M. Bal, Xavier Romero Ros & Hergen Spits
Published online: 02 February 2017
p164 | doi:10.1038/nrrheum.2016.218
Innate lymphoid cells are important players in the innate immune response, and might also contribute to inflammatory diseases. This Review discusses what is known about these cells and how they might be targeted in future therapies for these diseases.
Abstract | Full Text | PDF

Mixing omics: combining genetics and metabolomics to study rheumatic diseases
Cristina Menni, Jonas Zierer, Ana M. Valdes & Tim D. Spector
Published online: 02 February 2017
p174 | doi:10.1038/nrrheum.2017.5
Metabolomics and genomics approaches have produced huge amounts of data from patient samples, creating many research opportunities. In this Review, the authors discuss how these datasets can be brought together to enrich our knowledge of rheumatic diseases.
Abstract | Full Text | PDF | Supplementary information

 
PERSPECTIVES
Top
OPINION
Cartilage-targeting drug delivery: can electrostatic interactions help?
Ambika G. Bajpayee & Alan J. Grodzinsky
Published online: 09 February 2017
p183 | doi:10.1038/nrrheum.2016.210
Current osteoarthritis therapies cannot sufficiently target cartilage and guarantee a biological response owing to limitations in the delivery methods. This Perspectives article discusses how electrostatic interactions can be utilized to increase drug penetration and retention in cartilage to provide sustained intra-tissue delivery.
Abstract | Full Text | PDF

Corrigendum: Autophagy: controlling cell fate in rheumatic diseases
Jason S. Rockel & Mohit Kapoor
Published online: 09 February 2017
p193 | doi:10.1038/nrrheum.2017.17

Full Text | PDF
Erratum: Insight into rheumatological cause and effect through the use of Mendelian randomization
Philip C. Robinson, Hyon K. Choi, Ron Do & Tony R. Merriman
Published online: 22 February 2017
p193 | doi:10.1038/nrrheum.2017.18

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